PMID- 35880361
OWN - NLM
STAT- MEDLINE
DCOM- 20220727
LR  - 20220809
IS  - 1827-675X (Electronic)
IS  - 0392-100X (Print)
IS  - 0392-100X (Linking)
VI  - 42
IP  - 3
DP  - 2022 Jun
TI  - Long-term outcomes and quality of life following parotidectomy for benign 
      disease.
PG  - 215-222
LID - 10.14639/0392-100X-N1728 [doi]
AB  - OBJECTIVE: Parotidectomy worsens quality of life (QoL) in the short-term, but the 
      long-term impact is unknown. In this study, we analysed the long-term effects of 
      parotidectomy on QoL. METHODS: In this prospective long-term follow-up study, 
      participants were divided into three groups: short-term (ST) follow-up of six 
      weeks, long-term (LT) follow-up of 13 years and short- and long-term (SLT) 
      follow-up. QoL was assessed using the Parotidectomy Outcome Inventory (POI-8). 
      Parotidectomies were classified based on whether the great auricular nerve (GAN) 
      had been preserved or sacrificed. RESULTS: In total, 164 observations were 
      analysed, 74 in the LT group, 57 in the ST group and 33 in the SLT group. 
      Hypoaesthesia was a major problem and facial palsy was a minor problem. Pain (p < 
      0.01) and hypoaesthesia (p < 0.001) were significantly lower after 13 years 
      compared with after six weeks, and QoL was higher after 13 years compared with 
      after six weeks (p = 0.04). The disease-specific impairment rate decreased from 
      70% at short-term follow-up to 30% at long-term follow-up. Removal of the GAN was 
      associated with hypoaesthesia in the ST group (p = 0.028). CONCLUSIONS: 
      Hypoaesthesia has a long-term impact on the QoL, and this should be emphasised 
      during preoperative discussions.
CI  - Copyright (c) 2022 Societa Italiana di Otorinolaringoiatria e Chirurgia 
      Cervico-Facciale, Rome, Italy.
FAU - Plath, Michaela
AU  - Plath M
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital 
      Heidelberg, Heidelberg, Germany.
FAU - Sand, Matthias
AU  - Sand M
AD  - GESIS-Leibniz-Institute for the Social Sciences, Mannheim, Germany.
FAU - Cavaliere, Carlo
AU  - Cavaliere C
AD  - Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, 
      Italy.
FAU - Plinkert, Peter K
AU  - Plinkert PK
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital 
      Heidelberg, Heidelberg, Germany.
FAU - Baumann, Ingo
AU  - Baumann I
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital 
      Heidelberg, Heidelberg, Germany.
FAU - Zaoui, Karim
AU  - Zaoui K
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital 
      Heidelberg, Heidelberg, Germany.
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Acta Otorhinolaryngol Ital
JT  - Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di 
      otorinolaringologia e chirurgia cervico-facciale
JID - 8213019
SB  - IM
MH  - Follow-Up Studies
MH  - Humans
MH  - Hypesthesia
MH  - Parotid Gland/surgery
MH  - *Parotid Neoplasms/surgery
MH  - Postoperative Complications/epidemiology
MH  - Prospective Studies
MH  - *Quality of Life
PMC - PMC9330751
OTO - NOTNLM
OT  - POI-8
OT  - benign disease
OT  - long-term outcome
OT  - parotidectomy
OT  - quality of life
EDAT- 2022/07/27 06:00
MHDA- 2022/07/28 06:00
PMCR- 2022/06/01
CRDT- 2022/07/26 03:52
PHST- 2021/06/07 00:00 [received]
PHST- 2021/11/19 00:00 [accepted]
PHST- 2022/07/26 03:52 [entrez]
PHST- 2022/07/27 06:00 [pubmed]
PHST- 2022/07/28 06:00 [medline]
PHST- 2022/06/01 00:00 [pmc-release]
AID - 10.14639/0392-100X-N1728 [doi]
PST - ppublish
SO  - Acta Otorhinolaryngol Ital. 2022 Jun;42(3):215-222. doi: 
      10.14639/0392-100X-N1728.