PMID- 35882040
OWN - NLM
STAT- MEDLINE
DCOM- 20221010
LR  - 20221012
IS  - 1536-3732 (Electronic)
IS  - 1049-2275 (Linking)
VI  - 33
IP  - 7
DP  - 2022 Oct 1
TI  - Changes in Tears Monocyte Chemoattractant Protein-1 Level After External 
      Dacryocystorhinostomy in Primary Acquired Nasolacrimal Duct Obstruction.
PG  - e776-e779
LID - 10.1097/SCS.0000000000008723 [doi]
AB  - BACKGROUND: The authors aimed to define tears monocyte chemoattractant protein-1 
      (MCP-1) changes after external dacryocystorhinostomy surgery. MATERIALS AND 
      METHODS: Tears samples were collected with a Schirmer strip and stored in 
      Eppendorf tubes at -80 degrees C. At the end of the study, the papers were cut into small 
      pieces and incubated with phosphate-buffered saline solution. Monocyte 
      chemoattractant protein-1 levels were determined by using an enzyme-linked 
      immunosorbent assays kit. RESULTS: The MCP-1 levels were 498.66+/-101.35, 
      576.40+/-149.78, 422.53+/-85.94, and 436.96+/-81.38 ng/L before surgery, in the first 
      week, the first, and third months after surgery, respectively. Its level 
      significantly increased in the first week compared with the preoperative level ( 
      P <0.001). There was a prominent decrease in the postoperative first month ( P 
      <0.001). In the third postoperative month, the mean MCP-1 level was not 
      significantly increased compared with the postoperative first month ( P =0.196). 
      CONCLUSION: The tears MCP-1 level was significantly decreased after external 
      dacryocystorhinostomy surgery.
CI  - Copyright (c) 2022 by Mutaz B. Habal, MD.
FAU - Karabulut, Mujdat
AU  - Karabulut M
AD  - Department of Ophthalmology, Mugla Sitki Kocman University Training and Research 
      Hospital.
FAU - Saruhan, Ercan
AU  - Saruhan E
AD  - Department of Medical Biochemistry, Faculty of Medicine, Mugla Sitki Kocman 
      University, Mugla, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20220726
PL  - United States
TA  - J Craniofac Surg
JT  - The Journal of craniofacial surgery
JID - 9010410
RN  - 0 (Chemokine CCL2)
RN  - 0 (Phosphates)
RN  - 0 (Saline Solution)
MH  - Chemokine CCL2
MH  - *Dacryocystorhinostomy
MH  - Humans
MH  - *Lacrimal Duct Obstruction
MH  - *Nasolacrimal Duct/surgery
MH  - Phosphates
MH  - Saline Solution
MH  - Treatment Outcome
COIS- The authors report no conflicts of interest.
EDAT- 2022/07/27 06:00
MHDA- 2022/10/12 06:00
CRDT- 2022/07/26 17:42
PHST- 2022/03/14 00:00 [received]
PHST- 2022/03/22 00:00 [accepted]
PHST- 2022/07/27 06:00 [pubmed]
PHST- 2022/10/12 06:00 [medline]
PHST- 2022/07/26 17:42 [entrez]
AID - 00001665-202210000-00111 [pii]
AID - 10.1097/SCS.0000000000008723 [doi]
PST - ppublish
SO  - J Craniofac Surg. 2022 Oct 1;33(7):e776-e779. doi: 10.1097/SCS.0000000000008723. 
      Epub 2022 Jul 26.