PMID- 35884320
OWN - NLM
STAT- MEDLINE
DCOM- 20220728
LR  - 20220731
IS  - 2079-6374 (Electronic)
IS  - 2079-6374 (Linking)
VI  - 12
IP  - 7
DP  - 2022 Jul 12
TI  - Magnetoimpedance Biosensors and Real-Time Healthcare Monitors: Progress, 
      Opportunities, and Challenges.
LID - 10.3390/bios12070517 [doi]
LID - 517
AB  - A small DC magnetic field can induce an enormous response in the impedance of a 
      soft magnetic conductor in various forms of wire, ribbon, and thin film. Also 
      known as the giant magnetoimpedance (GMI) effect, this phenomenon forms the basis 
      for the development of high-performance magnetic biosensors with magnetic field 
      sensitivity down to the picoTesla regime at room temperature. Over the past 
      decade, some state-of-the-art prototypes have become available for trial tests 
      due to continuous efforts to improve the sensitivity of GMI biosensors for the 
      ultrasensitive detection of biological entities and biomagnetic field detection 
      of human activities through the use of magnetic nanoparticles as biomarkers. In 
      this review, we highlight recent advances in the development of GMI biosensors 
      and review medical devices for applications in biomedical diagnostics and 
      healthcare monitoring, including real-time monitoring of respiratory motion in 
      COVID-19 patients at various stages. We also discuss exciting research 
      opportunities and existing challenges that will stimulate further study into 
      ultrasensitive magnetic biosensors and healthcare monitors based on the GMI 
      effect.
FAU - Jimenez, Valery Ortiz
AU  - Jimenez VO
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
FAU - Hwang, Kee Young
AU  - Hwang KY
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
FAU - Nguyen, Dang
AU  - Nguyen D
AUID- ORCID: 0000-0002-9622-8370
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
AD  - Department of Biomedical Engineering, University of South Florida, Tampa, FL 
      33620, USA.
FAU - Rahman, Yasif
AU  - Rahman Y
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
FAU - Albrecht, Claire
AU  - Albrecht C
AUID- ORCID: 0000-0003-3887-2683
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
FAU - Senator, Baylee
AU  - Senator B
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
FAU - Thiabgoh, Ongard
AU  - Thiabgoh O
AD  - Department of Physics, Faculty of Science, Ubon Ratchathani University, 
      Warinchamrap, Ubon Ratchathani 34190, Thailand.
FAU - Devkota, Jagannath
AU  - Devkota J
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
AD  - National Energy Technology Laboratory, Pittsburgh, PA 15236, USA.
FAU - Bui, Vinh Duc An
AU  - Bui VDA
AUID- ORCID: 0000-0002-3833-5709
AD  - Hue Central Hospital, Hue 52000, Vietnam.
FAU - Lam, Dao Son
AU  - Lam DS
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
AD  - Institute of Materials Science, Vietnam Academy of Science and Technology, 18 
      Hoang Quoc Viet, Ha Noi 10072, Vietnam.
FAU - Eggers, Tatiana
AU  - Eggers T
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
FAU - Phan, Manh-Huong
AU  - Phan MH
AD  - Laboratory for Advanced Materials and Sensors, Department of Physics, University 
      of South Florida, Tampa, FL 33620, USA.
LA  - eng
GR  - 125300/University of South Florida/
PT  - Journal Article
PT  - Review
DEP - 20220712
PL  - Switzerland
TA  - Biosensors (Basel)
JT  - Biosensors
JID - 101609191
SB  - IM
MH  - *Biosensing Techniques
MH  - *COVID-19/diagnosis
MH  - Delivery of Health Care
MH  - Electric Impedance
MH  - Humans
MH  - Magnetics
PMC - PMC9313129
OTO - NOTNLM
OT  - COVID-19 detection
OT  - healthcare monitors
OT  - magnetic biosensors
OT  - magnetoimpedance
COIS- The authors declare no conflict of interest.
EDAT- 2022/07/28 06:00
MHDA- 2022/07/29 06:00
PMCR- 2022/07/12
CRDT- 2022/07/27 01:09
PHST- 2022/05/13 00:00 [received]
PHST- 2022/06/30 00:00 [revised]
PHST- 2022/07/08 00:00 [accepted]
PHST- 2022/07/27 01:09 [entrez]
PHST- 2022/07/28 06:00 [pubmed]
PHST- 2022/07/29 06:00 [medline]
PHST- 2022/07/12 00:00 [pmc-release]
AID - bios12070517 [pii]
AID - biosensors-12-00517 [pii]
AID - 10.3390/bios12070517 [doi]
PST - epublish
SO  - Biosensors (Basel). 2022 Jul 12;12(7):517. doi: 10.3390/bios12070517.