PMID- 35885674
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220731
IS  - 2075-4418 (Print)
IS  - 2075-4418 (Electronic)
IS  - 2075-4418 (Linking)
VI  - 12
IP  - 7
DP  - 2022 Jul 21
TI  - Autoimmune Connective Tissue Diseases-Related Pruritus: Proper Diagnosis and 
      Possible Mechanisms.
LID - 10.3390/diagnostics12071772 [doi]
LID - 1772
AB  - Pruritus is a well-known bothersome symptom among skin disorders, especially 
      inflammatory skin disorders. Lately, a high prevalence of pruritus in patients 
      with autoimmune connective tissue diseases (ACTDs) has been revealed. Patients 
      with ACTDs may suffer from varying degrees of pruritus, which affect their 
      quality of life. However, it is rarely recognized both by patients and 
      physicians. Meanwhile, pruritus is not only a symptom but is also related to the 
      disease severity of some ACTDs. The pathophysiology of ACTD related pruritus is 
      ambiguous. This review summarizes the features and possible mechanisms of 
      ACTD-related pruritus, which might lead to proper diagnosis and treatment.
FAU - Wong, Lai-San
AU  - Wong LS
AUID- ORCID: 0000-0002-7807-4670
AD  - Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung 
      University College of Medicine, Kaohsiung 83301, Taiwan.
FAU - Yen, Yu-Ta
AU  - Yen YT
AD  - Department of Dermatology, Fooying University Hospital, Pentong 928, Taiwan.
AD  - Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung 
      80420, Taiwan.
LA  - eng
GR  - CMRPG8L0831/Chang Gung Medical Research Program/
PT  - Journal Article
PT  - Review
DEP - 20220721
PL  - Switzerland
TA  - Diagnostics (Basel)
JT  - Diagnostics (Basel, Switzerland)
JID - 101658402
PMC - PMC9317505
OTO - NOTNLM
OT  - autoimmune diseases
OT  - pruritus
OT  - small fiber neuropathy
COIS- The authors declare no conflict of interest.
EDAT- 2022/07/28 06:00
MHDA- 2022/07/28 06:01
PMCR- 2022/07/21
CRDT- 2022/07/27 01:16
PHST- 2022/06/13 00:00 [received]
PHST- 2022/07/05 00:00 [revised]
PHST- 2022/07/20 00:00 [accepted]
PHST- 2022/07/27 01:16 [entrez]
PHST- 2022/07/28 06:00 [pubmed]
PHST- 2022/07/28 06:01 [medline]
PHST- 2022/07/21 00:00 [pmc-release]
AID - diagnostics12071772 [pii]
AID - diagnostics-12-01772 [pii]
AID - 10.3390/diagnostics12071772 [doi]
PST - epublish
SO  - Diagnostics (Basel). 2022 Jul 21;12(7):1772. doi: 10.3390/diagnostics12071772.