PMID- 35885844
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220731
IS  - 2227-9032 (Print)
IS  - 2227-9032 (Electronic)
IS  - 2227-9032 (Linking)
VI  - 10
IP  - 7
DP  - 2022 Jul 16
TI  - Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review 
      and Meta-Analysis.
LID - 10.3390/healthcare10071318 [doi]
LID - 1318
AB  - BACKGROUND: The aim of the present study was to determine the prevalence and 
      incidence of diabetic retinopathy (DR) and its changes in the last 20 years in 
      type 2 diabetes mellitus (T2DM) patients in Spain. METHODS: A systematic review 
      with a meta-analysis was carried out on the studies published between 2001-2020 
      on the prevalence and incidence of DR and sight-threatening diabetic retinopathy 
      (STDR) in Spain. The articles included were selected from four databases and 
      publications of the Spanish Ministry of Health and Regional Health Care System 
      (RHCS). The meta-analysis to determine heterogeneity and bias between studies was 
      carried out with the MetaXL 4.0. RESULTS: Since 2001, we have observed an 
      increase in the detection of patients with DM, and at the same time, screening 
      programs for RD have been launched; thus, we can deduce that the increase in the 
      detection of patients with DM, many of them in the initial phases, far exceeds 
      the increased detection of patients with DR. The prevalence of DR was higher 
      between 2001 and 2008 with values of 28.85%. These values decreased over the 
      following period between 2009 and 2020 with a mean of 15.28%. Similarly the STDR 
      prevalence decrease from 3.67% to 1.92% after 2008. The analysis of the 
      longitudinal studies determined that the annual DR incidence was 3.83%, and the 
      STDR annual incidence was 0.41%. CONCLUSION: In Spain, for T2DM, the current 
      prevalence of DR is 15.28% and 1.92% forSTDR. The annual incidence of DR is 3.83% 
      and is 0.41% for STDR.
FAU - Romero-Aroca, Pedro
AU  - Romero-Aroca P
AUID- ORCID: 0000-0002-7061-8987
AD  - Ophthalmic Department, University Hospital Sant Joan, Institut de Investigacio 
      Sanitaries Pere Virgili, Universitat Rovira & Virgili, 43204 Reus, Spain.
FAU - Lopez-Galvez, Maribel
AU  - Lopez-Galvez M
AD  - Ophthalmic Department, IOBA, Hospital Clinico Universitario de Valladolid, 47003 
      Valladolid, Spain.
FAU - Martinez-Brocca, Maria Asuncion
AU  - Martinez-Brocca MA
AUID- ORCID: 0000-0001-9740-122X
AD  - Comprehensive Healthcare Plan for Diabetes, Regional Ministry of Health and 
      Families of Andalusia, Government of Andalusia, 14071 Seville, Spain.
FAU - Pareja-Rios, Alicia
AU  - Pareja-Rios A
AD  - Ophthalmic Department, Hospital Universitario de Canarias, Carretera Ofra S/N, 
      38320 San Cristobal de La Laguna, Spain.
FAU - Artola, Sara
AU  - Artola S
AD  - Family Physiacian, Health Care Center Jose Marva, 28020 Madrid, Spain.
FAU - Franch-Nadal, Josep
AU  - Franch-Nadal J
AUID- ORCID: 0000-0002-5175-1555
AD  - EAP Raval Sud-Gerencia Territorial Barcelona, Institut Catala de la Salut, IDIAP 
      Jordi Gol/CIBERDEM (IIB Sant Pau), 08006 Barcelona, Spain.
FAU - Fernandez-Ballart, Joan
AU  - Fernandez-Ballart J
AUID- ORCID: 0000-0002-1320-6484
AD  - Area of Preventive Medicine and Public Health, Faculty of Medicine and Health 
      Sciences, Institut d'Investigacions Sanitaries Pere i Virgili, Universitat Rovira 
      i Virgili (URV), 43003 Tarragona, Spain.
AD  - CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn) Instituto Carlos III, 
      28029 Madrid, Spain.
FAU - Andonegui, Jose
AU  - Andonegui J
AUID- ORCID: 0000-0002-3109-3743
AD  - Department of Ophthalmology, Hospital Universitario de Navarra, IdiSNA, Navarra 
      Institute for Health Research, 31009 Pamplona, Spain.
FAU - Baget-Bernaldiz, Marc
AU  - Baget-Bernaldiz M
AD  - Ophthalmic Department, University Hospital Sant Joan, Institut de Investigacio 
      Sanitaries Pere Virgili, Universitat Rovira & Virgili, 43204 Reus, Spain.
LA  - eng
GR  - PI18 / 00169/Instituto de Salud Carlos III/
GR  - European Regional Development fund [FEDER],/FEDER/
PT  - Journal Article
PT  - Review
DEP - 20220716
PL  - Switzerland
TA  - Healthcare (Basel)
JT  - Healthcare (Basel, Switzerland)
JID - 101666525
PMC - PMC9320037
OTO - NOTNLM
OT  - diabetes mellitus
OT  - diabetic retinopathy incidence
OT  - diabetic retinopathy prevalence
OT  - epidemiology
OT  - meta-analysis
OT  - screening
OT  - systematic review
COIS- The authors declare no conflict of interest.
EDAT- 2022/07/28 06:00
MHDA- 2022/07/28 06:01
PMCR- 2022/07/16
CRDT- 2022/07/27 01:16
PHST- 2022/05/22 00:00 [received]
PHST- 2022/07/03 00:00 [revised]
PHST- 2022/07/07 00:00 [accepted]
PHST- 2022/07/27 01:16 [entrez]
PHST- 2022/07/28 06:00 [pubmed]
PHST- 2022/07/28 06:01 [medline]
PHST- 2022/07/16 00:00 [pmc-release]
AID - healthcare10071318 [pii]
AID - healthcare-10-01318 [pii]
AID - 10.3390/healthcare10071318 [doi]
PST - epublish
SO  - Healthcare (Basel). 2022 Jul 16;10(7):1318. doi: 10.3390/healthcare10071318.