PMID- 35886569
OWN - NLM
STAT- MEDLINE
DCOM- 20220728
LR  - 20220830
IS  - 1660-4601 (Electronic)
IS  - 1661-7827 (Print)
IS  - 1660-4601 (Linking)
VI  - 19
IP  - 14
DP  - 2022 Jul 18
TI  - NBI and Laryngeal Papillomatosis: A Diagnostic Challenge: A Systematic Review.
LID - 10.3390/ijerph19148716 [doi]
LID - 8716
AB  - Narrow-band imaging (NBI) represents a valid aid in laryngeal squamous cell 
      carcinoma (LSCC) diagnosis for detecting vascular changes. However, LSCC and 
      laryngeal papillomatosis (LP) show similar vascular patterns that may lead to 
      misdiagnosis and improper treatment. This review aims to deepen this NBI limit in 
      order to stress a careful preoperative evaluation of laryngeal lesions. The 
      research was carried out on PubMed, Web of Science and Scopus databases using 
      specific keywords. The topic of research was assessed by these parameters: 
      accuracy, sensitivity, specificity, and positive and negative predictive values. 
      This review included only five articles: they demonstrated that NBI is better 
      than white-light endoscopy in detecting LSCC and LP. They also reported that LP 
      is frequently mistaken for LSCC, resulting in high rates of false positives using 
      NBI. This is the first review that emphasized this NBI limitation in 
      distinguishing between LP and LSCC in cases of a type V pattern of 
      intraepithelial papillary capillary loop. Although NBI application increased the 
      rate of early cancer detection, LP reduces NBI accuracy. This drawback may lead 
      to misdiagnosis and improper treatment. Our advice is to be careful in cases of 
      type V pattern on NBI and to research LP epithelial and clinical features because 
      it could be a pitfall.
FAU - Saraniti, Carmelo
AU  - Saraniti C
AUID- ORCID: 0000-0002-1072-0736
AD  - Division of Otorhinolaryngology, Department of Biomedicine, Neuroscience and 
      Advanced Diagnostic, University of Palermo, 90127 Palermo, Italy.
FAU - Gallina, Salvatore
AU  - Gallina S
AD  - Division of Otorhinolaryngology, Department of Biomedicine, Neuroscience and 
      Advanced Diagnostic, University of Palermo, 90127 Palermo, Italy.
FAU - Verro, Barbara
AU  - Verro B
AUID- ORCID: 0000-0002-1940-5281
AD  - Division of Otorhinolaryngology, Department of Biomedicine, Neuroscience and 
      Advanced Diagnostic, University of Palermo, 90127 Palermo, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20220718
PL  - Switzerland
TA  - Int J Environ Res Public Health
JT  - International journal of environmental research and public health
JID - 101238455
RN  - Laryngeal papillomatosis
SB  - IM
MH  - Humans
MH  - *Laryngeal Neoplasms/diagnostic imaging
MH  - Laryngoscopy/methods
MH  - Narrow Band Imaging/methods
MH  - *Papilloma/diagnostic imaging/pathology
MH  - Sensitivity and Specificity
PMC - PMC9317038
OTO - NOTNLM
OT  - diagnosis
OT  - differential diagnosis
OT  - laryngeal papillomatosis
OT  - larynx
OT  - narrow-band imaging
OT  - papilloma
COIS- The authors declare no conflict of interest.
EDAT- 2022/07/28 06:00
MHDA- 2022/07/29 06:00
PMCR- 2022/07/18
CRDT- 2022/07/27 01:20
PHST- 2022/06/13 00:00 [received]
PHST- 2022/07/14 00:00 [revised]
PHST- 2022/07/16 00:00 [accepted]
PHST- 2022/07/27 01:20 [entrez]
PHST- 2022/07/28 06:00 [pubmed]
PHST- 2022/07/29 06:00 [medline]
PHST- 2022/07/18 00:00 [pmc-release]
AID - ijerph19148716 [pii]
AID - ijerph-19-08716 [pii]
AID - 10.3390/ijerph19148716 [doi]
PST - epublish
SO  - Int J Environ Res Public Health. 2022 Jul 18;19(14):8716. doi: 
      10.3390/ijerph19148716.