PMID- 35889283
OWN - NLM
STAT- MEDLINE
DCOM- 20220728
LR  - 20220731
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 27
IP  - 14
DP  - 2022 Jul 9
TI  - Dissipation Residue Behaviors and Dietary Risk Assessment of Boscalid and 
      Pyraclostrobin in Watermelon by HPLC-MS/MS.
LID - 10.3390/molecules27144410 [doi]
LID - 4410
AB  - Fungicides containing active ingredients of boscalid and pyraclostrobin have been 
      widely applied in watermelon disease control. To provide data for avoiding health 
      hazards caused by fungicides, we investigated its terminal residues and evaluated 
      the dietary risk. In this work, watermelon samples were collected from field 
      sites in six provinces and analyzed with high-performance liquid 
      chromatography-tandem mass spectrometry (HPLC-MS/MS). The average recoveries of 
      boscalid and pyraclostrobin in the watermelon matrix were 97-108% and 93-103%, 
      respectively, with the relative standard deviations (RSDs) </= 9.1%. The limits of 
      quantifications (LOQs) were 0.01 and 0.005 mg/kg for boscalid and pyraclostrobin. 
      Twenty-one days after applying the test pesticide with 270 g a.i./ha, the 
      terminal residues of boscalid and pyraclostrobin were all below 0.05 mg/kg and 
      below the maximum residue limits (MRLs) recommended by European Food Safety 
      Authority (EFSA). According to the national estimated daily intake (NEDI), the 
      risk quotients (RQs) of boscalid and pyraclostrobin were 48.4% and 62.6%, 
      respectively. That indicated the pesticide evaluated in watermelon exhibited a 
      low dietary risk to consumers. All data provide a reference for the MRL 
      establishment of boscalid in watermelon for China.
FAU - Lv, Le
AU  - Lv L
AD  - School of Chemistry and Biological Engineering, University of Science and 
      Technology Beijing, Beijing 100083, China.
FAU - Su, Yue
AU  - Su Y
AD  - School of Chemistry and Biological Engineering, University of Science and 
      Technology Beijing, Beijing 100083, China.
FAU - Dong, Bizhang
AU  - Dong B
AD  - School of Chemistry and Biological Engineering, University of Science and 
      Technology Beijing, Beijing 100083, China.
FAU - Lu, Wang
AU  - Lu W
AD  - School of Chemistry and Biological Engineering, University of Science and 
      Technology Beijing, Beijing 100083, China.
FAU - Hu, Jiye
AU  - Hu J
AD  - School of Chemistry and Biological Engineering, University of Science and 
      Technology Beijing, Beijing 100083, China.
FAU - Liu, Xiaolu
AU  - Liu X
AUID- ORCID: 0000-0003-4034-963X
AD  - School of Chemistry and Biological Engineering, University of Science and 
      Technology Beijing, Beijing 100083, China.
LA  - eng
GR  - FRF-BR-20-03B/Fundamental Research Funds for the Central Universities/
PT  - Journal Article
DEP - 20220709
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 0 (Biphenyl Compounds)
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Pesticide Residues)
RN  - 0 (Pesticides)
RN  - 0 (Strobilurins)
RN  - 25X51I8RD4 (Niacinamide)
RN  - 32MS8ZRD1V (2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide)
RN  - DJW8M9OX1H (pyrachlostrobin)
SB  - IM
MH  - Biphenyl Compounds
MH  - Chromatography, High Pressure Liquid
MH  - *Citrullus
MH  - *Fungicides, Industrial/chemistry
MH  - Niacinamide/analogs & derivatives
MH  - *Pesticide Residues/analysis
MH  - *Pesticides/analysis
MH  - Risk Assessment
MH  - Strobilurins
MH  - Tandem Mass Spectrometry/methods
PMC - PMC9318032
OTO - NOTNLM
OT  - MRL establishment
OT  - boscalid
OT  - dietary risk assessment
OT  - pyraclostrobin
OT  - watermelon
COIS- The authors declare no conflict of interest.
EDAT- 2022/07/28 06:00
MHDA- 2022/07/29 06:00
PMCR- 2022/07/09
CRDT- 2022/07/27 01:34
PHST- 2022/06/06 00:00 [received]
PHST- 2022/06/28 00:00 [revised]
PHST- 2022/07/05 00:00 [accepted]
PHST- 2022/07/27 01:34 [entrez]
PHST- 2022/07/28 06:00 [pubmed]
PHST- 2022/07/29 06:00 [medline]
PHST- 2022/07/09 00:00 [pmc-release]
AID - molecules27144410 [pii]
AID - molecules-27-04410 [pii]
AID - 10.3390/molecules27144410 [doi]
PST - epublish
SO  - Molecules. 2022 Jul 9;27(14):4410. doi: 10.3390/molecules27144410.