PMID- 35900095 OWN - NLM STAT- MEDLINE DCOM- 20230323 LR - 20230323 IS - 1945-2403 (Electronic) IS - 0146-4760 (Linking) VI - 47 IP - 2 DP - 2023 Mar 21 TI - Amphetamines in Workplace Testing Hair Samples over the Years 2011-2020. PG - 197-205 LID - 10.1093/jat/bkac055 [doi] AB - Amphetamines (AMPs) in hair were investigated with thousands of workplace testing head and body hair samples collected and analyzed over 10 years and tabulated by year. All samples were washed by a published extensive method prior to confirmation by liquid chromatography-mass spectrometry-mass spectrometry. Presented are concentrations of parent methamphetamine (METH), 3,4-methylenedioxymethamphetamine (MDMA) and methylenedioxyamphetamine as metabolite and AMP as metabolite and without the presence of parent drug. Some differences in METH concentrations from year to year were significant, and some ratios of metabolite to parent drug for both METH and MDMA also varied significantly. While rates of METH use may not have changed significantly, some aspects of the drugs ingested as demonstrated by hair analysis varied over the 10-year period. CI - (c) The Author(s) 2022. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. FAU - Hill, Virginia A AU - Hill VA AUID- ORCID: 0000-0001-5052-3414 AD - Psychemedics Corporation, 5832 Uplander Way, Culver City, CA 90230, USA. FAU - Schaffer, Michael I AU - Schaffer MI AD - Psychemedics Corporation, 5832 Uplander Way, Culver City, CA 90230, USA. FAU - Paulsen, Ryan B AU - Paulsen RB AD - Psychemedics Corporation, 5832 Uplander Way, Culver City, CA 90230, USA. FAU - Stowe, G Neil AU - Stowe GN AD - Psychemedics Corporation, 5832 Uplander Way, Culver City, CA 90230, USA. LA - eng PT - Journal Article PL - England TA - J Anal Toxicol JT - Journal of analytical toxicology JID - 7705085 RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) RN - 0 (Amphetamines) RN - 44RAL3456C (Methamphetamine) SB - IM MH - *N-Methyl-3,4-methylenedioxyamphetamine/analysis MH - Substance Abuse Detection/methods MH - Amphetamines/analysis MH - *Methamphetamine/analysis MH - Hair/chemistry MH - Workplace EDAT- 2022/07/29 06:00 MHDA- 2023/03/24 06:00 CRDT- 2022/07/28 09:03 PHST- 2021/12/17 00:00 [received] PHST- 2022/03/02 00:00 [revised] PHST- 2022/07/26 00:00 [accepted] PHST- 2022/07/29 06:00 [pubmed] PHST- 2023/03/24 06:00 [medline] PHST- 2022/07/28 09:03 [entrez] AID - 6651056 [pii] AID - 10.1093/jat/bkac055 [doi] PST - ppublish SO - J Anal Toxicol. 2023 Mar 21;47(2):197-205. doi: 10.1093/jat/bkac055.