PMID- 35905807 OWN - NLM STAT- MEDLINE DCOM- 20220831 LR - 20220914 IS - 1873-507X (Electronic) IS - 0031-9384 (Linking) VI - 255 DP - 2022 Oct 15 TI - Comparisons of auditory brainstem response elicited by compound click-sawtooths sound and synthetic consonant-vowel /da/. PG - 113922 LID - S0031-9384(22)00228-1 [pii] LID - 10.1016/j.physbeh.2022.113922 [doi] AB - The auditory brainstem response to complex sounds (cABR) could be evoked using speech sounds such as the 40 ms synthetic consonant-vowel syllable /da/ (CV-da) that was commonly used in basic and clinical research. cABR consists of responses to formant energy as well as the energy of fundamental frequency. The co-existence of the two energy makes cABR a mixed response. We introduced a new stimulus of click-sawtooths (CSW) with similar time-lock patterns but without formant or harmonic energy. Ten young healthy volunteers were recruited and the cABRs of CV-da and CSW of their 20 ears were acquired. The response latencies, amplitudes, and frequency-domain analytic results were compared pairwisely between stimuli. The response amplitudes were significantly greater for CSW and the latencies were significantly shorter for CSW. The latency-intensity functions were also greater for CSW. For CSW, adjustments of energy component can be made without causing biased changes to the other. CSW may be used in future basic research and clinical applications. CI - Copyright (c) 2022. Published by Elsevier Inc. FAU - Lee, Guo-She AU - Lee GS AD - Department of Otolaryngology, School of Medicine, College of Medicine, Yangming Campus, National Yang Ming Chiao Tung University, Taipei, Taiwan and Department of Otolaryngology, Taipei City Hospital, Renai Branch, Taipei, Taiwan. Electronic address: guosheli@gmail.com. FAU - Chang, Chen-Wei AU - Chang CW AD - Department of Speech Language Pathology and Audiology, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan. Electronic address: ychi1020@gmail.com. LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20220726 PL - United States TA - Physiol Behav JT - Physiology & behavior JID - 0151504 SB - IM MH - Acoustic Stimulation MH - Evoked Potentials, Auditory/physiology MH - *Evoked Potentials, Auditory, Brain Stem/physiology MH - Humans MH - Phonetics MH - Reaction Time/physiology MH - Sound MH - *Speech Perception/physiology OTO - NOTNLM OT - Auditory brainstem response OT - Click-sawtooth OT - Complex sound OT - Syllables EDAT- 2022/07/30 06:00 MHDA- 2022/09/01 06:00 CRDT- 2022/07/29 19:13 PHST- 2022/03/21 00:00 [received] PHST- 2022/07/14 00:00 [revised] PHST- 2022/07/24 00:00 [accepted] PHST- 2022/07/30 06:00 [pubmed] PHST- 2022/09/01 06:00 [medline] PHST- 2022/07/29 19:13 [entrez] AID - S0031-9384(22)00228-1 [pii] AID - 10.1016/j.physbeh.2022.113922 [doi] PST - ppublish SO - Physiol Behav. 2022 Oct 15;255:113922. doi: 10.1016/j.physbeh.2022.113922. Epub 2022 Jul 26.