PMID- 35907579 OWN - NLM STAT- MEDLINE DCOM- 20221214 LR - 20221221 IS - 1879-1131 (Electronic) IS - 0738-081X (Linking) VI - 40 IP - 6 DP - 2022 Nov-Dec TI - Subacute cutaneous lupus erythematosus: A facultative paraneoplastic dermatosis. PG - 728-742 LID - S0738-081X(22)00094-3 [pii] LID - 10.1016/j.clindermatol.2022.07.007 [doi] AB - Subacute cutaneous lupus erythematosus (SCLE) is a photosensitive dermatosis characterized by a nonscarring papulosquamous eruption and specific antibodies in the patient's serum. Genetic and environmental factors represent the leading causes of SCLE; however, several case reports in the literature link SCLE to various types of cancer. This review assesses the association between SCLE and neoplastic disorders. A PubMed search was performed for all relevant publications on cancer-associated SCLE from 1982 to 2022. This review supports the hypothesis that SCLE should be considered a facultative paraneoplastic phenomenon. It also emphasizes the importance of cancer screening in patients presenting SCLE manifestations. CI - Copyright (c) 2022 Elsevier Inc. All rights reserved. FAU - Lazar, Andrada Luciana AU - Lazar AL AD - Department of Dermatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania. Electronic address: andradalucianalazar@yahoo.com. LA - eng PT - Journal Article PT - Review DEP - 20220728 PL - United States TA - Clin Dermatol JT - Clinics in dermatology JID - 8406412 RN - 0 (Autoantibodies) SB - IM MH - Humans MH - *Lupus Erythematosus, Cutaneous/complications/diagnosis MH - Autoantibodies MH - *Photosensitivity Disorders EDAT- 2022/07/31 06:00 MHDA- 2022/12/15 06:00 CRDT- 2022/07/30 19:24 PHST- 2022/07/31 06:00 [pubmed] PHST- 2022/12/15 06:00 [medline] PHST- 2022/07/30 19:24 [entrez] AID - S0738-081X(22)00094-3 [pii] AID - 10.1016/j.clindermatol.2022.07.007 [doi] PST - ppublish SO - Clin Dermatol. 2022 Nov-Dec;40(6):728-742. doi: 10.1016/j.clindermatol.2022.07.007. Epub 2022 Jul 28.