PMID- 35913889
OWN - NLM
STAT- MEDLINE
DCOM- 20221014
LR  - 20221019
IS  - 1938-5404 (Electronic)
IS  - 0033-7587 (Linking)
VI  - 198
IP  - 4
DP  - 2022 Oct 1
TI  - Chromosomal Aberrations in Large Japanese Field Mice (Apodemus speciosus) 
      Captured in Various Periods after Fukushima Daiichi Nuclear Power Plant Accident.
PG  - 347-356
LID - 10.1667/RADE-21-00162.1 [doi]
AB  - After the Fukushima Daiichi Nuclear Power Plant accident, we studied the 
      chromosomal aberrations (dicentrics and translocations) in the splenic 
      lymphocytes of wild mice inhabiting Fukushima prefecture. Here, we report the 
      frequencies of chromosomal aberrations in large Japanese field mice (Apodemus 
      speciosus) captured from 2012 to 2016 in a heavily contaminated area. The 
      chromosomal aberrations were detected using newly developed 4-color FISH 
      (fluorescence in situ hybridization) with A. speciosus chromosome 1-, 3-, 4- and 
      5-specific painting probes. The frequencies of chromosomal aberrations in mice 
      captured in July 2012 and October 2014 were significantly higher than that in the 
      mice inhabiting the non-contaminated control area; however, the frequency of 
      chromosomal aberrations in mice captured in January 2016 was not. The frequency 
      of chromosomal aberrations in individual mice tended to increase with certain 
      dose rates and accumulated doses. Regression tree analyses suggested increasing 
      chromosomal aberration rate in mice exposed to chronic radiation at dose rates of 
      more than 1.1 mGy day-1 and at accumulated doses of more than 200 mGy. It is 
      concluded that ambient dose rates in the most severely contaminated area of 
      Fukushima prefecture and radiation doses to wild mice inhabiting this area 
      decrease with time; consequently, chromosomal aberrations induced by radiation 
      have not been detected 5 years after the accident.
CI  - (c)2022 by Radiation Research Society. All rights of reproduction in any form 
      reserved.
FAU - Shiomi, Naoko
AU  - Shiomi N
AD  - Department of Radioecology and Fukushima Project, National Institute of 
      Radiological Sciences, Quantum Medical Science Directorate, National Institute 
      for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, 
      Chiba 263-8555, Japan.
FAU - Takahashi, Hiroyuki
AU  - Takahashi H
AD  - Tokyo Nuclear Services Co., Ltd. 1-3-5 Taito, Taito-ku, Tokyo 110-0016, Japan.
FAU - Watanabe, Yoshito
AU  - Watanabe Y
AD  - Department of Radioecology and Fukushima Project, National Institute of 
      Radiological Sciences, Quantum Medical Science Directorate, National Institute 
      for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, 
      Chiba 263-8555, Japan.
FAU - Fuma, Shoichi
AU  - Fuma S
AD  - Department of Radioecology and Fukushima Project, National Institute of 
      Radiological Sciences, Quantum Medical Science Directorate, National Institute 
      for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, 
      Chiba 263-8555, Japan.
FAU - Aoki, Masanari
AU  - Aoki M
AD  - Japan Wildlife Research Center, 3-3-7 Kotobashi, Sumida-ku, Tokyo 130-8606, 
      Japan.
FAU - Kubota, Masahide
AU  - Kubota M
AD  - Japan Wildlife Research Center, 3-3-7 Kotobashi, Sumida-ku, Tokyo 130-8606, 
      Japan.
FAU - Furuhata, Yoshiaki
AU  - Furuhata Y
AD  - Japan Wildlife Research Center, 3-3-7 Kotobashi, Sumida-ku, Tokyo 130-8606, 
      Japan.
FAU - Morosawa, Takahiro
AU  - Morosawa T
AD  - Japan Wildlife Research Center, 3-3-7 Kotobashi, Sumida-ku, Tokyo 130-8606, 
      Japan.
FAU - Kubota, Yoshihisa
AU  - Kubota Y
AD  - Department of Radioecology and Fukushima Project, National Institute of 
      Radiological Sciences, Quantum Medical Science Directorate, National Institute 
      for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, 
      Chiba 263-8555, Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Radiat Res
JT  - Radiation research
JID - 0401245
SB  - IM
MH  - Animals
MH  - Chromosome Aberrations
MH  - *Fukushima Nuclear Accident
MH  - In Situ Hybridization, Fluorescence
MH  - Japan
MH  - Mice
MH  - Murinae/genetics
MH  - Nuclear Power Plants
MH  - Radiation Dosage
EDAT- 2022/08/02 06:00
MHDA- 2022/10/15 06:00
CRDT- 2022/08/01 13:12
PHST- 2021/08/18 00:00 [received]
PHST- 2022/06/23 00:00 [accepted]
PHST- 2022/08/02 06:00 [pubmed]
PHST- 2022/10/15 06:00 [medline]
PHST- 2022/08/01 13:12 [entrez]
AID - 484477 [pii]
AID - 10.1667/RADE-21-00162.1 [doi]
PST - ppublish
SO  - Radiat Res. 2022 Oct 1;198(4):347-356. doi: 10.1667/RADE-21-00162.1.