PMID- 35919887
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220805
IS  - 2752-4191 (Electronic)
IS  - 2752-4191 (Linking)
VI  - 1
IP  - 3
DP  - 2021 Nov
TI  - Impact of gamification on glycaemic control among patients with type 2 diabetes 
      mellitus: a systematic review and meta-analysis of randomized controlled trials.
PG  - oeab030
LID - 10.1093/ehjopen/oeab030 [doi]
LID - oeab030
AB  - AIMS : The prevalence of type 2 diabetes mellitus (T2DM) is very high and still 
      rising. Optimal medical therapy and lifestyle management are essential in 
      reducing the long-term complications of T2DM. Gamification, which is the use of 
      design elements, and characteristics of games in a non-gaming context, is an 
      innovative approach to improve healthy behaviour. It thereby could be able to 
      improve glycaemic control in T2DM. The aim of this systematic review and 
      meta-analysis is to evaluate the effect of gamification on glycaemic control 
      expressed by haemoglobin A1c (HbA1c) levels in T2DM patients. METHODS AND 
      RESULTS : All articles from 2000 to 2021 were searched in electronic databases 
      (PubMed, Cochrane Library, Embase). The total number of patients was 704. The 
      rate of male participants and their mean ages ranged, respectively, from 46% to 
      94% and 60 to 63 years. Inclusion criteria were randomized controlled trials of 
      T2DM management using gamification which included HbA1c as an outcome measure. A 
      meta-analysis was performed. After removing duplicates, 129 articles were 
      screened and a total of 3 articles corresponding to the inclusion criteria were 
      identified. Haemoglobin A1c was significantly reduced [mean difference -0.21; 95% 
      confidence interval (-0.37 to -0.05); P = 0.01; I (2) = 0%] in the intervention 
      group using gamification as compared to the control group. CONCLUSION : 
      Gamification has a positive effect on glycaemic control expressed by HbA1c 
      changes in patients with T2DM. However, only three studies were included in this 
      review. More research is needed to confirm the effectiveness of gamification in 
      T2DM.
CI  - (c) The Author(s) 2021. Published by Oxford University Press on behalf of the 
      European Society of Cardiology.
FAU - Kaihara, Toshiki
AU  - Kaihara T
AUID- ORCID: 0000-0003-0941-8035
AD  - Heart Centre Hasselt, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium.
AD  - Faculty of Medicine and Life Sciences, Hasselt University, Agoralaan gebouw D, 
      3590 Diepenbeek, Belgium.
AD  - Division of Cardiology, Department of Internal Medicine, St. Marianna University 
      School of Medicine, 2-16-1 Sugao, Miyamae Ward, 216-8511 Kawasaki, Japan.
FAU - Intan-Goey, Valent
AU  - Intan-Goey V
AD  - Heart Centre Hasselt, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium.
FAU - Scherrenberg, Martijn
AU  - Scherrenberg M
AUID- ORCID: 0000-0001-9483-3828
AD  - Heart Centre Hasselt, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium.
AD  - Faculty of Medicine and Life Sciences, Hasselt University, Agoralaan gebouw D, 
      3590 Diepenbeek, Belgium.
AD  - Faculty of Medicine and Health Sciences, University of Antwerp, Campus Drie Eiken 
      Building S, Universiteitsplein 1, 2610 Wilrijk, Belgium.
FAU - Falter, Maarten
AU  - Falter M
AUID- ORCID: 0000-0001-7407-115X
AD  - Heart Centre Hasselt, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium.
AD  - Faculty of Medicine and Life Sciences, Hasselt University, Agoralaan gebouw D, 
      3590 Diepenbeek, Belgium.
AD  - KULeuven, Faculty of Medicine, Department of Cardiology, Herestraat 49, 3000 
      Leuven, Belgium.
FAU - Frederix, Ines
AU  - Frederix I
AUID- ORCID: 0000-0001-8636-5972
AD  - Heart Centre Hasselt, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium.
AD  - Faculty of Medicine and Life Sciences, Hasselt University, Agoralaan gebouw D, 
      3590 Diepenbeek, Belgium.
AD  - Faculty of Medicine and Health Sciences, University of Antwerp, Campus Drie Eiken 
      Building S, Universiteitsplein 1, 2610 Wilrijk, Belgium.
AD  - Department of Cardiology, Antwerp University Hospital, Drie Eikenstraat 655, 2650 
      Edegem, Belgium.
FAU - Akashi, Yoshihiro
AU  - Akashi Y
AUID- ORCID: 0000-0001-7670-7326
AD  - Division of Cardiology, Department of Internal Medicine, St. Marianna University 
      School of Medicine, 2-16-1 Sugao, Miyamae Ward, 216-8511 Kawasaki, Japan.
FAU - Dendale, Paul
AU  - Dendale P
AUID- ORCID: 0000-0003-0821-4559
AD  - Heart Centre Hasselt, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium.
AD  - Faculty of Medicine and Life Sciences, Hasselt University, Agoralaan gebouw D, 
      3590 Diepenbeek, Belgium.
LA  - eng
PT  - Journal Article
DEP - 20211018
PL  - England
TA  - Eur Heart J Open
JT  - European heart journal open
JID - 9918282081406676
PMC - PMC9242065
OTO - NOTNLM
OT  - Gamification
OT  - Randomized controlled trial
OT  - Secondary prevention
OT  - Type 2 diabetes mellitus
EDAT- 2022/08/04 06:00
MHDA- 2022/08/04 06:01
PMCR- 2021/10/18
CRDT- 2022/08/03 02:14
PHST- 2021/07/19 00:00 [received]
PHST- 2021/08/16 00:00 [revised]
PHST- 2021/10/16 00:00 [accepted]
PHST- 2022/08/03 02:14 [entrez]
PHST- 2022/08/04 06:00 [pubmed]
PHST- 2022/08/04 06:01 [medline]
PHST- 2021/10/18 00:00 [pmc-release]
AID - oeab030 [pii]
AID - 10.1093/ehjopen/oeab030 [doi]
PST - epublish
SO  - Eur Heart J Open. 2021 Oct 18;1(3):oeab030. doi: 10.1093/ehjopen/oeab030. 
      eCollection 2021 Nov.