PMID- 35933097
OWN - NLM
STAT- MEDLINE
DCOM- 20221005
LR  - 20221214
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 166
DP  - 2022 Oct
TI  - Comparing Patient-Reported Outcomes in Patients Undergoing Lumbar Fusion for 
      Isthmic Spondylolisthesis with Predominant Back Pain versus Predominant Leg Pain 
      Symptoms.
PG  - e672-e680
LID - S1878-8750(22)01022-1 [pii]
LID - 10.1016/j.wneu.2022.07.074 [doi]
AB  - OBJECTIVE: To compare patient-reported outcome measures (PROMs) and minimum 
      clinically important difference (MCID) achievement following anterior or 
      transforaminal lumbar interbody fusion for isthmic spondylolisthesis in patients 
      presenting with predominant back pain versus predominant leg pain symptoms. 
      METHODS: A single-surgeon database was reviewed for anterior or transforaminal 
      lumbar interbody fusion procedures for isthmic spondylolisthesis. Patient 
      demographics, perioperative characteristics, postoperative complications, and 
      PROMs were collected. Demographic/perioperative characteristics were compared 
      among groups using chi(2) and Student t tests for categorical and continuous 
      variables, respectively. Mean PROM scores were compared using an unpaired Student 
      t test. Postoperative improvement from preoperative baseline within each cohort 
      was assessed with paired-samples t test. MCID achievement rates were compared 
      with chi(2) analysis. RESULTS: In total, 143 patients were included with 65 
      patients in the predominant back pain and 78 patients in the predominant leg pain 
      cohort. Preoperative visual analog scale (VAS) leg was noted to be significantly 
      greater in predominant leg pain cohort (P < 0.001). Cohorts demonstrated 
      significant mean postoperative differences for the following PROMs at the 
      following postoperative time points: significant differences were noted between 
      cohorts for rate of achievement of MCID for the following PROMs at the following 
      time points: VAS back at 2 years and VAS leg at 6 weeks/12 weeks/6 months/overall 
      (P < 0.036, all). CONCLUSIONS: Compared with patients presenting for surgery with 
      predominant leg pain symptoms, patients undergoing lumbar fusion at L4-L5 and 
      L5-S1 for isthmic spondylolisthesis with predominant back pain symptoms may 
      demonstrate improved long-term clinical outcomes for reported back pain, leg 
      pain, and disability and reduced postoperative length of stay and narcotic 
      consumption.
CI  - Copyright (c) 2022 Elsevier Inc. All rights reserved.
FAU - Jacob, Kevin C
AU  - Jacob KC
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Patel, Madhav R
AU  - Patel MR
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Vanjani, Nisheka N
AU  - Vanjani NN
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Pawlowski, Hanna
AU  - Pawlowski H
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Prabhu, Michael C
AU  - Prabhu MC
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Singh, Kern
AU  - Singh K
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA. Electronic address: kern.singh@rushortho.com.
LA  - eng
PT  - Journal Article
DEP - 20220804
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
RN  - 0 (Narcotics)
SB  - IM
MH  - Back Pain/etiology/surgery
MH  - Humans
MH  - Lumbar Vertebrae/surgery
MH  - Minimally Invasive Surgical Procedures
MH  - Narcotics
MH  - Patient Reported Outcome Measures
MH  - Retrospective Studies
MH  - *Spinal Fusion/methods
MH  - *Spondylolisthesis/complications/surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - ALIF
OT  - Back pain
OT  - Isthmic spondylolisthesis
OT  - Leg pain outcomes
OT  - TLIF
EDAT- 2022/08/07 06:00
MHDA- 2022/10/06 06:00
CRDT- 2022/08/06 19:28
PHST- 2022/04/29 00:00 [received]
PHST- 2022/07/14 00:00 [revised]
PHST- 2022/07/15 00:00 [accepted]
PHST- 2022/08/07 06:00 [pubmed]
PHST- 2022/10/06 06:00 [medline]
PHST- 2022/08/06 19:28 [entrez]
AID - S1878-8750(22)01022-1 [pii]
AID - 10.1016/j.wneu.2022.07.074 [doi]
PST - ppublish
SO  - World Neurosurg. 2022 Oct;166:e672-e680. doi: 10.1016/j.wneu.2022.07.074. Epub 
      2022 Aug 4.