PMID- 35935186 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220809 IS - 1664-302X (Print) IS - 1664-302X (Electronic) IS - 1664-302X (Linking) VI - 13 DP - 2022 TI - Recent advances in the study of NADC34-like porcine reproductive and respiratory syndrome virus in China. PG - 950402 LID - 10.3389/fmicb.2022.950402 [doi] LID - 950402 AB - Since porcine reproductive and respiratory syndrome virus (PRRSV) was first described in China in 1996, several genetically distinct strains of PRRSV have emerged with varying pathogenicity and severity, thereby making the prevention and control of PRRS more difficult in China and worldwide. Between 2017 and 2021, the detection rate of NADC34-like strain in China increased. To date, NADC34-like strains have spread to 10 Chinese provinces and have thus developed different degrees of pathogenicity and mortality. In this review, we summarize the history of NADC34-like strains in China and clarify the prevalence, genomic characteristics, restriction fragment length polymorphisms, recombination, pathogenicity, and vaccine status of this strain in China. In so doing, this study aims to provide a basis for the further development of prevention and control measures targeting the NADC34-like strain. CI - Copyright (c) 2022 Zhao, Wang, Han, Guo, Liu, Hou, Wang, Zheng, Wang and Wen. FAU - Zhao, Hong-Zhe AU - Zhao HZ AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Wang, Feng-Xue AU - Wang FX AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Han, Xiao-Yu AU - Han XY AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Guo, Hao AU - Guo H AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Liu, Chun-Yu AU - Liu CY AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Hou, Li-Na AU - Hou LN AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Wang, Ya-Xin AU - Wang YX AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Zheng, Hui AU - Zheng H AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Wang, Lu AU - Wang L AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. FAU - Wen, Yong-Jun AU - Wen YJ AD - Key Laboratory for Clinical Diagnosis and Treatment of Animal Diseases of Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China. LA - eng PT - Journal Article PT - Review DEP - 20220722 PL - Switzerland TA - Front Microbiol JT - Frontiers in microbiology JID - 101548977 PMC - PMC9354828 OTO - NOTNLM OT - NADC34-like OT - PRRSV OT - RFLP OT - pathogenicity OT - recombination COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2022/08/09 06:00 MHDA- 2022/08/09 06:01 PMCR- 2022/07/22 CRDT- 2022/08/08 03:28 PHST- 2022/05/22 00:00 [received] PHST- 2022/06/30 00:00 [accepted] PHST- 2022/08/08 03:28 [entrez] PHST- 2022/08/09 06:00 [pubmed] PHST- 2022/08/09 06:01 [medline] PHST- 2022/07/22 00:00 [pmc-release] AID - 10.3389/fmicb.2022.950402 [doi] PST - epublish SO - Front Microbiol. 2022 Jul 22;13:950402. doi: 10.3389/fmicb.2022.950402. eCollection 2022.