PMID- 35945847
OWN - NLM
STAT- MEDLINE
DCOM- 20220811
LR  - 20220811
IS  - 1999-6217 (Electronic)
IS  - 1727-5482 (Linking)
VI  - 20
IP  - 1
DP  - 2022 Jun 2
TI  - Prevalence of Gestational Diabetes Mellitus in Nepal: A Systematic Review and 
      Meta-analysis.
PG  - 12-20
LID - 10.33314/jnhrc.v20i01.3874 [doi]
AB  - BACKGROUND: Gestational diabetes mellitus is a condition of glucose intolerance 
      during pregnancy. The burden of Gestational diabetes mellitus is ever increasing 
      including a lower middle-income country like Nepal. METHODS: This meta-analysis 
      was conducted in accordance to the guidance of the Preferred Reporting Items for 
      Systematic Reviews and Meta-Analyses statement. Databases of "Embase", "Google 
      Scholar", "Scopus", "Web of Science" were searched for observational studies in 
      Nepal from 2000 to July 2021. Random effect model was used to estimate the pooled 
      prevalence subgroup analysis. RESULTS: This systematic review and meta-analysis 
      analyzed 9 studies with a total of 20865 participants. Pooled prevalence of 
      gestational diabetes mellitus was 2.61% (95% CI: 1.25- 5.37). From subgroup 
      analysis, the prevalence of Gestational diabetes mellitus according to the 
      diagnostic criteria were: International Association of Diabetes and Pregnancy 
      Study Groups (IADPSG) criteria 6.56% (95% CI: 4.79-8.92), World Health 
      Organization (WHO) criteria 4.81% (95% CI: 3.79-6.08), Diabetes in Pregnancy 
      Study Group of India (DIPSI) criteria 4.71% (95% CI: 3.06-7.18), Carpenter and 
      Coustan criteria (CC) 1.08% (95% CI: 0.43-2.71); prevalence according to the 
      publication time: before 2015 1.20% (95% CI: 3.64-6.41), in and after 2015 4.84% 
      (95% CI: 0.42-3.39); prevalence according to the place: within Kathmandu valley 
      2.70% (95% CI: 1.17-6.08), outside Kathmandu valley 2.28% (95% CI: 0.26-17.15). 
      CONCLUSION: Our study revealed the increasing prevalence of GDM in Nepal. Further 
      large observational studies at local levels are essential to measure the actual 
      burden, risk factors and potential preventive measures for Gestational diabetes 
      mellitus.
FAU - Pokharel, Pashupati
AU  - Pokharel P
AD  - Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
FAU - Pokhrel, Kailash Mani
AU  - Pokhrel KM
AD  - Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
FAU - Lamichhane, Pratik
AU  - Lamichhane P
AD  - Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
FAU - Khanal, Kapil
AU  - Khanal K
AD  - Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
FAU - Rawal, Suniti
AU  - Rawal S
AD  - Department of Gynecology and Obstetrics, Tribhuvan University Teaching Hospital, 
      Kathmandu, Nepal.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20220602
PL  - Nepal
TA  - J Nepal Health Res Counc
JT  - Journal of Nepal Health Research Council
JID - 101292936
SB  - IM
MH  - *Diabetes, Gestational/diagnosis/epidemiology
MH  - Female
MH  - *Glucose Intolerance
MH  - Humans
MH  - Nepal/epidemiology
MH  - Pregnancy
MH  - Prevalence
MH  - Risk Factors
OTO - NOTNLM
OT  - Diabetes in pregnancy; gestational diabetes mellitus; meta-analysis; Nepal; 
      prevalence.
EDAT- 2022/08/11 06:00
MHDA- 2022/08/12 06:00
CRDT- 2022/08/10 01:32
PHST- 2021/09/24 00:00 [received]
PHST- 2022/06/02 00:00 [accepted]
PHST- 2022/08/10 01:32 [entrez]
PHST- 2022/08/11 06:00 [pubmed]
PHST- 2022/08/12 06:00 [medline]
AID - 10.33314/jnhrc.v20i01.3874 [doi]
PST - epublish
SO  - J Nepal Health Res Counc. 2022 Jun 2;20(1):12-20. doi: 
      10.33314/jnhrc.v20i01.3874.