PMID- 35949589
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220813
IS  - 1792-1082 (Electronic)
IS  - 1792-1074 (Print)
IS  - 1792-1074 (Linking)
VI  - 24
IP  - 3
DP  - 2022 Sep
TI  - Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report.
PG  - 322
LID - 10.3892/ol.2022.13442 [doi]
LID - 322
AB  - Primary retroperitoneal perirenal CIC rearrangement sarcoma is rare. The current 
      case report presents a 69-year-old male patient with this pathology, including 
      the clinical features, pathomorphology and immunohistochemistry, and CIC gene 
      rupture detected by fluorescence in situ hybridization (FISH). Furthermore, the 
      relevant literature was reviewed. Histologically, the tumor was composed of 
      diffuse nests of small- to medium-sized juvenile round blue cells with 
      hyperchromatic nuclei, prominent nucleoli and occasional mitotic signs. The tumor 
      involved adipose tissue with no obvious hemorrhagic necrotic foci. 
      Immunohistochemistry indicated scattered expression of CD99 in tumor cells. FISH 
      examination suggested that the CIC gene was fragmented and translocated.
CI  - Copyright: (c) Yang et al.
FAU - Yang, Junjie
AU  - Yang J
AD  - Department of Pathology, The First People's Hospital of Xiaoshan District, 
      Hangzhou, Zhejiang 311200, P.R. China.
FAU - Liu, Hongsheng
AU  - Liu H
AD  - Department of Pathology, The First People's Hospital of Xiaoshan District, 
      Hangzhou, Zhejiang 311200, P.R. China.
FAU - Huang, Bin
AU  - Huang B
AD  - Department of Pathology, The First People's Hospital of Xiaoshan District, 
      Hangzhou, Zhejiang 311200, P.R. China.
LA  - eng
PT  - Journal Article
DEP - 20220720
PL  - Greece
TA  - Oncol Lett
JT  - Oncology letters
JID - 101531236
PMC - PMC9353764
OTO - NOTNLM
OT  - CIC rearrangement
OT  - retroperitoneal perirenal
OT  - sarcoma
COIS- The authors declare that they have no competing interests.
EDAT- 2022/08/12 06:00
MHDA- 2022/08/12 06:01
PMCR- 2022/07/20
CRDT- 2022/08/11 02:19
PHST- 2022/05/26 00:00 [received]
PHST- 2022/07/11 00:00 [accepted]
PHST- 2022/08/11 02:19 [entrez]
PHST- 2022/08/12 06:00 [pubmed]
PHST- 2022/08/12 06:01 [medline]
PHST- 2022/07/20 00:00 [pmc-release]
AID - OL-24-03-13442 [pii]
AID - 10.3892/ol.2022.13442 [doi]
PST - epublish
SO  - Oncol Lett. 2022 Jul 20;24(3):322. doi: 10.3892/ol.2022.13442. eCollection 2022 
      Sep.