PMID- 35961182
OWN - NLM
STAT- MEDLINE
DCOM- 20220908
LR  - 20220928
IS  - 1724-191X (Electronic)
IS  - 1120-1797 (Linking)
VI  - 101
DP  - 2022 Sep
TI  - Synchronous bilateral chest wall irradiation with regional nodal irradiation: A 
      literature review of techniques and a case study.
PG  - 50-61
LID - S1120-1797(22)02019-1 [pii]
LID - 10.1016/j.ejmp.2022.07.005 [doi]
AB  - The optimal radiotherapy technique for patients requiring both breasts or chest 
      walls simultaneous irradiation with or without regional nodal irradiation is 
      currently under investigation. In the last decade several publications present 
      case reports and case series of patients treated with adjuvant radiotherapy in 
      both breasts or chest walls for synchronous bilateral breast cancer (SBBC) with 
      modern radiotherapy techniques. This article presents a systematic review of 
      relevant literature as well as a case report of a SBBC patient who received 
      bilateral chest wall radiotherapy with regional nodal irradiation at our 
      institution with Truebeam - Edge Linear Accelerator. Solid evidence is provided 
      that the practice of avoiding adjuvant radiotherapy in SBBC out of fear of 
      toxicity with older radiotherapy techniques is outdated. Modern techniques can 
      safely and effectively deliver treatment to patients requiring both sides 
      irradiation and even in mastectomy patients in need of regional nodal 
      irradiation.
CI  - Copyright (c) 2022 Associazione Italiana di Fisica Medica e Sanitaria. Published by 
      Elsevier Ltd. All rights reserved.
FAU - Protopapa, Maria
AU  - Protopapa M
AD  - Mediterraneo General Hospital, Radiation Oncology and Radiosurgery Department, 
      Ilias st. 8-12, Glyfada, Greece. Electronic address: merryprotopapa@yahoo.fr.
FAU - Stroumbinis, Theodoros
AU  - Stroumbinis T
AD  - Mediterraneo General Hospital, Radiation Oncology and Radiosurgery Department, 
      Ilias st. 8-12, Glyfada, Greece.
FAU - Zygogianni, Anna
AU  - Zygogianni A
AD  - National and Kapodistrian University of Athens, Medical School, 1st Dpt of 
      Radiology, RT Unit, Aretaieion University Hospital, Greece.
FAU - Psarras, Michael
AU  - Psarras M
AD  - Mediterraneo General Hospital, Radiation Oncology and Radiosurgery Department, 
      Ilias st. 8-12, Glyfada, Greece.
FAU - Kouloulias, Vassilis
AU  - Kouloulias V
AD  - National and Kapodistrian University of Athens, Medical School, 2nd Dpt of 
      Radiology, RT Unit, ATTIKON University Hospital, Greece.
FAU - Platoni, Kalliopi
AU  - Platoni K
AD  - National and Kapodistrian University of Athens, Medical School, 2nd Dpt of 
      Radiology, RT Unit, ATTIKON University Hospital, Greece; National and 
      Kapodistrian University of Athens, Medical School, 2nd Dpt of Radiology, Medical 
      Physics Unit, ATTIKON University Hospital, Greece.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20220809
PL  - Italy
TA  - Phys Med
JT  - Physica medica : PM : an international journal devoted to the applications of 
      physics to medicine and biology : official journal of the Italian Association of 
      Biomedical Physics (AIFB)
JID - 9302888
SB  - IM
MH  - *Breast Neoplasms/radiotherapy/surgery
MH  - Female
MH  - Humans
MH  - Mastectomy
MH  - Radiotherapy Dosage
MH  - *Radiotherapy, Intensity-Modulated/methods
MH  - *Thoracic Wall
OTO - NOTNLM
OT  - Dosimetry
OT  - PRISMA guidelines
OT  - SBBC
OT  - Synchronous bilateral breast cancer
OT  - Systematic review
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2022/08/13 06:00
MHDA- 2022/09/09 06:00
CRDT- 2022/08/12 18:21
PHST- 2022/01/19 00:00 [received]
PHST- 2022/06/03 00:00 [revised]
PHST- 2022/07/26 00:00 [accepted]
PHST- 2022/08/13 06:00 [pubmed]
PHST- 2022/09/09 06:00 [medline]
PHST- 2022/08/12 18:21 [entrez]
AID - S1120-1797(22)02019-1 [pii]
AID - 10.1016/j.ejmp.2022.07.005 [doi]
PST - ppublish
SO  - Phys Med. 2022 Sep;101:50-61. doi: 10.1016/j.ejmp.2022.07.005. Epub 2022 Aug 9.