PMID- 35964912
OWN - NLM
STAT- MEDLINE
DCOM- 20230214
LR  - 20230223
IS  - 2667-2960 (Electronic)
IS  - 2667-2960 (Linking)
VI  - 64
IP  - 1
DP  - 2023 Jan-Feb
TI  - Personality Pathology and Functional Impairment in Patients With Hypochondriasis.
PG  - 28-34
LID - S2667-2960(22)00308-1 [pii]
LID - 10.1016/j.jaclp.2022.08.001 [doi]
AB  - BACKGROUND: Research indicates substantial co-occurance of personality pathology 
      and hypochondriasis, which both involve significant psychosocial impairment. 
      OBJECTIVE: This study sought to investigate the role of personality pathology for 
      explaining functional impairment in patients with hypochondriasis, while 
      accounting for the influence of health anxiety severity. METHODS: Patients 
      diagnosed with hypochondriasis (N = 84; 60% women) were administered interview- 
      and self-report instruments for personality pathology, health anxiety severity, 
      and functional impairment (general, social, and physical): The Structured 
      Clinical Interview for DSM-IV Axis II (SCID-II), the Personality Inventory for 
      DSM-5 (PID-5), the Short Health Anxiety Inventory (SHAI), the 36-item Short Form 
      health survey (SF-36), and the Global Assessment of Functioning (GAF). 
      Hierarchical regression analyses were performed with boot-strapping (1000 
      samples). RESULTS: Findings overall showed that personality pathology 
      incrementally explained functional impairment over the influence of health 
      anxiety severity. More specifically, findings revealed that the incremental 
      effect of PID-5 trait dimensions was substantially larger than the SCID-II 
      personality disorder criterion-count. Functional impairment was specifically 
      associated with SCID-II symptoms of Avoidant Personality disorder and dependent 
      personality disorder as well as PID-5 trait domains of negative affectivity, 
      detachment, and psychoticism. CONCLUSIONS: The findings highlight the potential 
      significance of personality pathology for understanding and clinical management 
      of functional impairment in patients with hypochondriasis. The personality 
      features that best explained functional impairment were avoidant personality 
      disorder and dependent personality disorder and, in particular, DSM-5 and the 
      International Classification of Diseases, 11th revision personality trait domains 
      of negative affectivity, detachment, and psychoticism.
CI  - Copyright (c) 2022 Academy of Consultation-Liaison Psychiatry. Published by 
      Elsevier Inc. All rights reserved.
FAU - Bach, Bo
AU  - Bach B
AD  - Psychiatric Research Unit, Center for Personality Disorder Research, Region 
      Zealand, Slagelse, Denmark; Department of Psychology, University of Southern 
      Denmark, Odense, Denmark. Electronic address: bbpn@regionsjaelland.dk.
FAU - Skjernov, Mathias
AU  - Skjernov M
AD  - Center for Functional Disorders, Region Zealand University Hospital, Koge, 
      Denmark.
FAU - Simonsen, Erik
AU  - Simonsen E
AD  - Psychiatric Research Unit, Center for Personality Disorder Research, Region 
      Zealand, Slagelse, Denmark; Department of Clinical Medicine, University of 
      Copenhagen, Copenhagen, Denmark.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220811
PL  - Netherlands
TA  - J Acad Consult Liaison Psychiatry
JT  - Journal of the Academy of Consultation-Liaison Psychiatry
JID - 101775059
SB  - IM
MH  - Humans
MH  - Female
MH  - Male
MH  - *Hypochondriasis/diagnosis/psychology
MH  - Personality Disorders/diagnosis/psychology
MH  - Personality
MH  - Regression Analysis
MH  - *Problem Behavior
OTO - NOTNLM
OT  - functioning
OT  - health anxiety
OT  - hypochondriasis
OT  - illness anxiety
OT  - personality
OT  - traits
EDAT- 2022/08/15 06:00
MHDA- 2023/02/15 06:00
CRDT- 2022/08/14 19:27
PHST- 2022/03/17 00:00 [received]
PHST- 2022/07/16 00:00 [revised]
PHST- 2022/08/08 00:00 [accepted]
PHST- 2022/08/15 06:00 [pubmed]
PHST- 2023/02/15 06:00 [medline]
PHST- 2022/08/14 19:27 [entrez]
AID - S2667-2960(22)00308-1 [pii]
AID - 10.1016/j.jaclp.2022.08.001 [doi]
PST - ppublish
SO  - J Acad Consult Liaison Psychiatry. 2023 Jan-Feb;64(1):28-34. doi: 
      10.1016/j.jaclp.2022.08.001. Epub 2022 Aug 11.