PMID- 35964997
OWN - NLM
STAT- MEDLINE
DCOM- 20220816
LR  - 20220825
IS  - 1937-6448 (Print)
IS  - 1937-6448 (Linking)
VI  - 371
DP  - 2022
TI  - The role of dendritic cells in the immune niche of the peritoneum.
PG  - 1-14
LID - S1937-6448(22)00057-0 [pii]
LID - 10.1016/bs.ircmb.2022.04.012 [doi]
AB  - Dendritic cells (DCs) are professional antigen presenting cells that play an 
      important role in the induction of T cell responses. Different subsets (cDC1s, 
      cDC2s, pDCs, and moDCs) were described based on the expression of different 
      surface markers and functions. In the context of peritoneum, DCs are also a key 
      population cell orchestrating immune responses against pathogens, malignant cells 
      and tissue-damage. Furthermore, they play an important role in the promotion of 
      an anti-inflammatory microenvironment, which is necessary to maintain tolerance 
      and adipocyte homeostasis. The aim of this review is to summarize the current 
      knowledge of the functional and phenotypic features of peritoneal DCs and shed 
      some light on the importance of these cells within this unique cavity and its 
      associated components: the omentum, the mesentery and gut-associated lymphoid 
      tissue (GALT).
CI  - Copyright (c) 2022 Elsevier Inc. All rights reserved.
FAU - Reparaz, David
AU  - Reparaz D
AD  - Centro de Investigacion Medica Aplicada (CIMA), Universidad de Navarra, Pamplona, 
      Spain; IdiSNA, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Spain; 
      CIBEREHD, Pamplona, Spain. Electronic address: dreparaz@alumni.unav.es.
FAU - Hommel, Mirja
AU  - Hommel M
AD  - Centro de Investigacion Medica Aplicada (CIMA), Universidad de Navarra, Pamplona, 
      Spain; IdiSNA, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Spain.
FAU - Navarro, Flor
AU  - Navarro F
AD  - Centro de Investigacion Medica Aplicada (CIMA), Universidad de Navarra, Pamplona, 
      Spain; IdiSNA, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Spain.
FAU - Llopiz, Diana
AU  - Llopiz D
AD  - Centro de Investigacion Medica Aplicada (CIMA), Universidad de Navarra, Pamplona, 
      Spain; IdiSNA, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Spain; 
      CIBEREHD, Pamplona, Spain. Electronic address: diallo@unav.es.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220621
PL  - Netherlands
TA  - Int Rev Cell Mol Biol
JT  - International review of cell and molecular biology
JID - 101475846
SB  - IM
MH  - *Dendritic Cells
MH  - Immune Tolerance
MH  - *Peritoneum
MH  - T-Lymphocytes
OTO - NOTNLM
OT  - Dendritic cells
OT  - Mesentery
OT  - Milky spots
OT  - Omentum
OT  - Peritoneal cavity
EDAT- 2022/08/15 06:00
MHDA- 2022/08/17 06:00
CRDT- 2022/08/14 21:03
PHST- 2022/08/14 21:03 [entrez]
PHST- 2022/08/15 06:00 [pubmed]
PHST- 2022/08/17 06:00 [medline]
AID - S1937-6448(22)00057-0 [pii]
AID - 10.1016/bs.ircmb.2022.04.012 [doi]
PST - ppublish
SO  - Int Rev Cell Mol Biol. 2022;371:1-14. doi: 10.1016/bs.ircmb.2022.04.012. Epub 
      2022 Jun 21.