PMID- 35965680
OWN - NLM
STAT- MEDLINE
DCOM- 20220816
LR  - 20221207
IS  - 1942-0994 (Electronic)
IS  - 1942-0900 (Print)
IS  - 1942-0994 (Linking)
VI  - 2022
DP  - 2022
TI  - Clinical Effect of Abdominal Massage Therapy on Blood Glucose and Intestinal 
      Microbiota in Patients with Type 2 Diabetes.
PG  - 2286598
LID - 10.1155/2022/2286598 [doi]
LID - 2286598
AB  - The aim of the study was to investigate the clinical effects of abdominal massage 
      on patients with type 2 diabetes mellitus (T2DM) and its influence on the 
      intestinal microflora. We conducted a randomized, controlled clinical trial. A 
      total of 60 patients with T2DM, who met the inclusion criteria, were randomly 
      allocated to the control group, the routine massage group, and the abdominal 
      massage group. The control group received health education and maintained their 
      hypoglycemic drug treatment plan. The routine massage group and the abdominal 
      massage group received different massage interventions. In addition to glucose 
      and lipid metabolism indicators, we quantitatively analyzed the gut microbiota to 
      assess the effects of massage on the intestinal microflora of patients with T2DM. 
      Compared with the control group, the abdominal massage improved levels of 
      glycated hemoglobin, total cholesterol, Enterobacter, and Bifidobacteria with 
      significant differences (P = 0.02, P = 0.03, P = 0.03, and P = 0.03). The 
      comparison within group showed that the levels of the four bacterial genera in 
      the abdominal massage group revealed significant differences before and after 
      treatment (P = 0.006, P < 0.001, P < 0.001, and P = 0.002). The comparison 
      between the routine massage group and the abdominal massage group was not 
      significantly different in all levels of test indices. The abdominal massage 
      group regulated levels of Enterobacter and Lactobacilli to a greater extent than 
      the routine massage group. Additionally, abdominal massage decreased Enterococcus 
      levels. The results of this study showed that abdominal massage has clinical 
      advantages over routine massage. Specifically, this intervention may correct 
      microflora disturbances to a certain extent.
CI  - Copyright (c) 2022 Ying Xie et al.
FAU - Xie, Ying
AU  - Xie Y
AUID- ORCID: 0000-0002-9535-8958
AD  - College of Acupuncture and Massage, Nanjing University of Chinese Medicine, 
      Nanjing, Jiangsu, China.
FAU - Huan, Meng-Ting
AU  - Huan MT
AUID- ORCID: 0000-0002-9641-9687
AD  - College of Acupuncture and Massage, Nanjing University of Chinese Medicine, 
      Nanjing, Jiangsu, China.
FAU - Sang, Jia-Jia
AU  - Sang JJ
AUID- ORCID: 0000-0003-1257-2498
AD  - Provincial Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu, China.
FAU - Luo, Song-Song
AU  - Luo SS
AUID- ORCID: 0000-0002-8547-8817
AD  - College of Acupuncture and Massage, Nanjing University of Chinese Medicine, 
      Nanjing, Jiangsu, China.
FAU - Kong, Xin-Tian
AU  - Kong XT
AUID- ORCID: 0000-0002-3898-7459
AD  - Changzhou Hospital of Traditional Chinese Medicine, Changzhou, Jiangsu, China.
FAU - Xie, Zhou-Yu
AU  - Xie ZY
AUID- ORCID: 0000-0003-2028-949X
AD  - College of Acupuncture and Massage, Nanjing University of Chinese Medicine, 
      Nanjing, Jiangsu, China.
FAU - Zheng, Shi-Hui
AU  - Zheng SH
AUID- ORCID: 0000-0002-1819-6959
AD  - College of Acupuncture and Massage, Nanjing University of Chinese Medicine, 
      Nanjing, Jiangsu, China.
FAU - Wei, Qing-Bo
AU  - Wei QB
AUID- ORCID: 0000-0002-3577-5661
AD  - College of Acupuncture and Massage, Nanjing University of Chinese Medicine, 
      Nanjing, Jiangsu, China.
FAU - Wu, Yun-Chuan
AU  - Wu YC
AUID- ORCID: 0000-0002-7059-9229
AD  - College of Acupuncture and Massage, Nanjing University of Chinese Medicine, 
      Nanjing, Jiangsu, China.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20220803
PL  - United States
TA  - Oxid Med Cell Longev
JT  - Oxidative medicine and cellular longevity
JID - 101479826
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Blood Glucose
MH  - *Diabetes Mellitus, Type 2/therapy
MH  - *Gastrointestinal Microbiome
MH  - Glycated Hemoglobin
MH  - Humans
MH  - Massage/methods
PMC - PMC9365616
COIS- The authors declare no conflicts of interest.
EDAT- 2022/08/16 06:00
MHDA- 2022/08/17 06:00
PMCR- 2022/08/03
CRDT- 2022/08/15 03:28
PHST- 2022/05/05 00:00 [received]
PHST- 2022/07/12 00:00 [revised]
PHST- 2022/07/25 00:00 [accepted]
PHST- 2022/08/15 03:28 [entrez]
PHST- 2022/08/16 06:00 [pubmed]
PHST- 2022/08/17 06:00 [medline]
PHST- 2022/08/03 00:00 [pmc-release]
AID - 10.1155/2022/2286598 [doi]
PST - epublish
SO  - Oxid Med Cell Longev. 2022 Aug 3;2022:2286598. doi: 10.1155/2022/2286598. 
      eCollection 2022.