PMID- 35966533 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230223 IS - 2297-055X (Print) IS - 2297-055X (Electronic) IS - 2297-055X (Linking) VI - 9 DP - 2022 TI - A head-to-head comparison of myocardial strain by fast-strain encoding and feature tracking imaging in acute myocardial infarction. PG - 949440 LID - 10.3389/fcvm.2022.949440 [doi] LID - 949440 AB - BACKGROUND: Myocardial infarction (MI) is a major cause of heart failure. Left ventricular adverse remodeling is common post-MI. Several studies have demonstrated a correlation between reduced myocardial strain and the development of adverse remodeling. Cardiac magnetic resonance (CMR) with fast-strain encoding (fast-SENC) or feature tracking (FT) enables rapid assessment of myocardial deformation. The aim of this study was to establish a head-to-head comparison of fast-SENC and FT in post-ST-elevated myocardial infarction (STEMI) patients, with clinical 2D speckle tracking echocardiography (2DEcho) as a reference. METHODS: Thirty patients treated with primary percutaneous coronary intervention for STEMI were investigated. All participants underwent CMR examination with late gadolinium enhancement, cine-loop steady-state free precession, and fast-SENC imaging using a 1.5T scanner as well as a 2DEcho. Global longitudinal strain (GLS), segmental longitudinal strain (SLS), global circumferential strain (GCS), and segmental circumferential strain (SCS) were assessed along with the MI scar extent. RESULTS: The GCS measurements from fast-SENC and FT were nearly identical: the mean difference was 0.01 (2.5)% (95% CI - 0.92 to 0.95). For GLS, fast-SENC values were higher than FT, with a mean difference of 1.8 (1.4)% (95% CI 1.31-2.35). Tests of significance for GLS did not show any differences between the MR methods and 2DEcho. Average strain in the infarct-related artery (IRA) segments compared to the remote myocardium was significantly lower for the left anterior descending artery and right coronary artery culprits but not for the left circumflex artery culprits. Fast-SENC displayed a higher area under the curve for detecting infarcted segments than FT for both SCS and SLS. CONCLUSION: GLS and GCS did not significantly differ between fast-SENC and FT. Both showed acceptable agreement with 2DEcho for longitudinal strain. Segments perfused by the IRA showed significantly reduced strain values compared to the remote myocardium. Fast-SENC presented a higher sensitivity and specificity for detecting infarcted segments than FT. CI - Copyright (c) 2022 El-Saadi, Engvall, Alfredsson, Karlsson, Martins, Sederholm, Faisal Zaman, Ebbers and Kihlberg. FAU - El-Saadi, Walid AU - El-Saadi W AD - Department of Internal Medicine, Ryhov County Hospital, Region Jonkoping County, Jonkoping, Sweden. AD - Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. FAU - Engvall, Jan Edvin AU - Engvall JE AD - Department of Clinical Physiology in Linkoping and Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. AD - Center for Medical Imaging Science and Visualization, Linkoping University, Linkoping, Sweden. FAU - Alfredsson, Joakim AU - Alfredsson J AD - Department of Cardiology in Linkoping and Department of Health Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. FAU - Karlsson, Jan-Erik AU - Karlsson JE AD - Department of Internal Medicine, Ryhov County Hospital, Region Jonkoping County, Jonkoping, Sweden. AD - Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. FAU - Martins, Marcelo AU - Martins M AD - Department of Radiology in Linkoping and Department of Health Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. FAU - Sederholm, Sofia AU - Sederholm S AD - Department of Cardiology in Linkoping and Department of Health Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. FAU - Faisal Zaman, Shaikh AU - Faisal Zaman S AD - Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. AD - Center for Medical Imaging Science and Visualization, Linkoping University, Linkoping, Sweden. FAU - Ebbers, Tino AU - Ebbers T AD - Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. AD - Center for Medical Imaging Science and Visualization, Linkoping University, Linkoping, Sweden. FAU - Kihlberg, Johan AU - Kihlberg J AD - Center for Medical Imaging Science and Visualization, Linkoping University, Linkoping, Sweden. AD - Department of Radiology in Linkoping and Department of Health Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden. LA - eng PT - Journal Article DEP - 20220728 PL - Switzerland TA - Front Cardiovasc Med JT - Frontiers in cardiovascular medicine JID - 101653388 EIN - Front Cardiovasc Med. 2023 Feb 02;10:1140214. PMID: 36818344 PMC - PMC9366255 OTO - NOTNLM OT - ST elevation myocardial infarction OT - cine magnetic resonance imaging OT - left ventricular dysfunction OT - left ventricular remodeling OT - myocardial ischemia OT - myocardial stunning COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2022/08/16 06:00 MHDA- 2022/08/16 06:01 PMCR- 2022/01/01 CRDT- 2022/08/15 03:43 PHST- 2022/05/20 00:00 [received] PHST- 2022/07/04 00:00 [accepted] PHST- 2022/08/15 03:43 [entrez] PHST- 2022/08/16 06:00 [pubmed] PHST- 2022/08/16 06:01 [medline] PHST- 2022/01/01 00:00 [pmc-release] AID - 10.3389/fcvm.2022.949440 [doi] PST - epublish SO - Front Cardiovasc Med. 2022 Jul 28;9:949440. doi: 10.3389/fcvm.2022.949440. eCollection 2022.