PMID- 35966733
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231221
IS  - 1741-427X (Print)
IS  - 1741-4288 (Electronic)
IS  - 1741-427X (Linking)
VI  - 2022
DP  - 2022
TI  - Effects of Warm Needle Acupuncture plus Xitong Waixi Lotion in Patients with Knee 
      Osteoarthritis: A Randomized Controlled Trial.
PG  - 5467712
LID - 10.1155/2022/5467712 [doi]
LID - 5467712
AB  - OBJECTIVE: To evaluate the effect of warm needle acupuncture plus Xitong Waixi 
      lotion on the levels of IL-1, TNF-alpha, and MMP-3 in patients with knee 
      osteoarthritis. METHODS: Eighty patients with knee osteoarthritis admitted to our 
      hospital from October 2019 to June 2021 were recruited and assigned via the 
      random number table method at a ratio of 1 : 1 to receive either Xitong Waixi 
      lotion (conventional group) or warm needle acupuncture plus Xitong Waixi lotion 
      (combined group). Outcome measures included clinical efficacy, inflammatory 
      cytokine level, Western Ontario and McMaster Universities Arthritis Index (WOMAC) 
      score, visual analogue scale (VAS) score, Hospital for Special Surgery (HSS) knee 
      score, and adverse reactions. RESULTS: Warm needle acupuncture plus Xitong Waixi 
      lotion was associated with a significantly higher clinical efficacy versus Xitong 
      Waixi lotion alone (P=0.006). Patients in the combined group had significantly 
      lower levels of interleukin (IL)-1, tumor necrosis factor-alpha (TNF-alpha), and matrix 
      metalloproteinase-3 (MMP-3) than those in the conventional group (P=0.020). Warm 
      needle acupuncture plus Xitong Waixi lotion resulted in significantly lower WOMAC 
      scores and VAS scores and higher HSS scores for the patients versus Xitong Waixi 
      lotion (P=0.012). The two groups had a similar incidence of adverse events 
      (P=0.068). CONCLUSION: Warm needle acupuncture plus Xitong Waixi lotion 
      effectively alleviates the inflammatory response and knee pain in patients with 
      knee osteoarthritis, with significant clinical effects and a high safety profile.
CI  - Copyright (c) 2022 Guanyun Sheng et al.
FAU - Sheng, Guanyun
AU  - Sheng G
AD  - Department of Orthopaedics, Liuzhou Traditional Chinese Medical Hospital, Guangxi 
      University of Chinese Medicine, Liuzhou 545001, China.
FAU - Yang, Jing
AU  - Yang J
AD  - Intensive Care Unit, Liuzhou Traditional Chinese Medical Hospital, Guangxi 
      University of Chinese Medicine, Liuzhou 545001, China.
FAU - Rong, Peng
AU  - Rong P
AD  - Graduate School, Guangxi University of Chinese Medicine, Nanning 530000, China.
FAU - Yang, Xueyi
AU  - Yang X
AUID- ORCID: 0000-0003-1624-191X
AD  - Department of Orthopaedics, Liuzhou Traditional Chinese Medical Hospital, Guangxi 
      University of Chinese Medicine, Liuzhou 545001, China.
LA  - eng
PT  - Journal Article
PT  - Retracted Publication
DEP - 20220804
PL  - United States
TA  - Evid Based Complement Alternat Med
JT  - Evidence-based complementary and alternative medicine : eCAM
JID - 101215021
RIN - Evid Based Complement Alternat Med. 2023 Dec 13;2023:9819740. PMID: 38125196
PMC - PMC9371882
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2022/08/16 06:00
MHDA- 2022/08/16 06:01
PMCR- 2022/08/04
CRDT- 2022/08/15 03:46
PHST- 2022/04/22 00:00 [received]
PHST- 2022/05/24 00:00 [revised]
PHST- 2022/06/23 00:00 [accepted]
PHST- 2022/08/15 03:46 [entrez]
PHST- 2022/08/16 06:00 [pubmed]
PHST- 2022/08/16 06:01 [medline]
PHST- 2022/08/04 00:00 [pmc-release]
AID - 10.1155/2022/5467712 [doi]
PST - epublish
SO  - Evid Based Complement Alternat Med. 2022 Aug 4;2022:5467712. doi: 
      10.1155/2022/5467712. eCollection 2022.