PMID- 35978718
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220819
IS  - 2051-3380 (Print)
IS  - 2051-3380 (Electronic)
IS  - 2051-3380 (Linking)
VI  - 10
IP  - 9
DP  - 2022 Sep
TI  - The IRIS paradox: Imaging findings in a case of PJP-IRIS.
PG  - e01014
LID - 10.1002/rcr2.1014 [doi]
LID - e01014
AB  - Immune reconstitution inflammatory syndrome (IRIS) in patients with human 
      immunodeficiency virus (HIV) and Pneumocystis jirovecii pneumonia infection 
      reflects an exaggerated inflammatory response of the host immune system to an 
      antigen, which is temporally related to recovery of the immune system. Clinical 
      manifestations include fever, cough, dyspnoea and hypoxia following the 
      commencement of antiretroviral therapy. Diagnosis is made on clinical and 
      radiological criteria with exclusion of other infective and non-infective causes. 
      Unrecognized, IRIS may be associated with significant morbidity and mortality. 
      Treatment with corticosteroids often results in prompt recovery. There is limited 
      literature on radiological findings of Pneumocystis jirovecii 
      pneumonia-associated IRIS. Here we describe cross-sectional imaging findings of 
      PJP-IRIS in a patient following commencement of antiretroviral therapy.
CI  - (c) 2022 The Authors. Respirology Case Reports published by John Wiley & Sons 
      Australia, Ltd on behalf of The Asian Pacific Society of Respirology.
FAU - Reddy, Taryn
AU  - Reddy T
AUID- ORCID: 0000-0003-4932-3065
AD  - Department of Medical Imaging The Prince Charles Hospital Brisbane Queensland 
      Australia.
FAU - Bajwa, Ramey
AU  - Bajwa R
AD  - Department of Thoracic Medicine The Prince Charles Hospital Brisbane Queensland 
      Australia.
FAU - Burke, Andrew
AU  - Burke A
AD  - Department of Thoracic Medicine The Prince Charles Hospital Brisbane Queensland 
      Australia.
LA  - eng
PT  - Case Reports
DEP - 20220811
PL  - United States
TA  - Respirol Case Rep
JT  - Respirology case reports
JID - 101631052
PMC - PMC9366264
OTO - NOTNLM
OT  - HIV
OT  - IRIS
OT  - Pneumocystis jiroveci
OT  - computed tomography
OT  - immune reconstitution syndrome
COIS- None declared.
EDAT- 2022/08/19 06:00
MHDA- 2022/08/19 06:01
PMCR- 2022/08/11
CRDT- 2022/08/18 02:05
PHST- 2022/06/30 00:00 [received]
PHST- 2022/07/24 00:00 [accepted]
PHST- 2022/08/18 02:05 [entrez]
PHST- 2022/08/19 06:00 [pubmed]
PHST- 2022/08/19 06:01 [medline]
PHST- 2022/08/11 00:00 [pmc-release]
AID - RCR21014 [pii]
AID - 10.1002/rcr2.1014 [doi]
PST - epublish
SO  - Respirol Case Rep. 2022 Aug 11;10(9):e01014. doi: 10.1002/rcr2.1014. eCollection 
      2022 Sep.