PMID- 35985055
OWN - NLM
STAT- MEDLINE
DCOM- 20221118
LR  - 20221118
IS  - 1873-6947 (Electronic)
IS  - 1744-3881 (Linking)
VI  - 49
DP  - 2022 Nov
TI  - Acupuncture in treating obesity combined with type 2 diabetes mellitus: A 
      systematic review and meta-analysis of randomized controlled clinical trials.
PG  - 101658
LID - S1744-3881(22)00126-8 [pii]
LID - 10.1016/j.ctcp.2022.101658 [doi]
AB  - BACKGROUND: and purpose: Most type 2 diabetes mellitus (T2DM) patients are 
      accompanied by overweight or obesity, and it is difficult to concurrently solve 
      these two issues with conventional treatment regimens without experiencing 
      adverse effects. While clinical practice demonstrates that acupuncture is 
      beneficial in treating obesity combined with T2DM, there is a lack of 
      evidence-based medicine to support this claim. The study aims to systematically 
      evaluate the efficacy and safety of acupuncture in treating obesity combined with 
      T2DM. METHODS: By searching eight electronic databases, we collected randomized 
      controlled trials on acupuncture in treating obesity combined with T2DM. Two 
      reviewers independently screened the literature, extracted the data, and assessed 
      the risk of bias in the included studies. Meta-analysis was then performed using 
      RevMan 5.4 software. RESULTS: A total of 13 randomized controlled trials (RCTs) 
      involving 993 patients were eventually included. Meta-analysis results 
      demonstrated the effective rate of clinical symptoms: [RR = 1.19, 95% CI: 1.11, 
      1.28, P < 0.00001]; body mass index: [MD = -2.11, 95% CI: -2.56, -1.66, 
      P < 0.00001]; fasting plasma glucose: [MD = -1.09, 95% CI: -1.60, -0.59, 
      P < 0.00001]; haemoglobin A1c: [MD = -0.58, 95% CI: -0.95, -0.20, P = 0.002]; 
      triglyceride: [MD = -0.29, 95% CI: -0.46, -0.11, P = 0.001]; waist circumference: 
      [MD = -5.36, 95% CI: -8.68, -2.05, P = 0.002]; body fat rate: [MD = -3.59, 95% 
      CI: -4.28, -2.90, P < 0.00001]. CONCLUSION: Current evidence suggests that 
      acupuncture has advantages in treating obesity combined with T2DM. However, due 
      to low-quality evidence of included research, additional large-sample and 
      high-quality research are required to validate the findings of this study.
CI  - Copyright (c) 2022. Published by Elsevier Ltd.
FAU - Wang, Ying
AU  - Wang Y
AD  - Nanchang Hongdu Hospital of Traditional Chinese Medicine, Nanchang, Jiangxi 
      Province, China. Electronic address: wangying_0607@126.com.
FAU - Xu, Guang-Nan
AU  - Xu GN
AD  - Tianjin University of Traditional Chinese Medicine, Tianjin, China; Nankai 
      Hospital of Traditional Chinese Medicine, Tianjin, China.
FAU - Wan, Ren-Hong
AU  - Wan RH
AD  - Tianjin University of Traditional Chinese Medicine, Tianjin, China.
FAU - Zhou, Xin
AU  - Zhou X
AD  - Tianjin University of Traditional Chinese Medicine, Tianjin, China.
FAU - Ma, Li-Ying
AU  - Ma LY
AD  - Tianjin University of Traditional Chinese Medicine, Tianjin, China.
FAU - Liu, Bing
AU  - Liu B
AD  - Tianjin University of Traditional Chinese Medicine, Tianjin, China.
FAU - Zhang, Yu-Yan
AU  - Zhang YY
AD  - Tianjin University of Traditional Chinese Medicine, Tianjin, China.
FAU - Zhou, Liang
AU  - Zhou L
AD  - Nanchang Hongdu Hospital of Traditional Chinese Medicine, Nanchang, Jiangxi 
      Province, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20220813
PL  - England
TA  - Complement Ther Clin Pract
JT  - Complementary therapies in clinical practice
JID - 101225531
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/therapy/drug therapy
MH  - Obesity/complications/therapy
MH  - *Acupuncture Therapy
MH  - Body Mass Index
MH  - Randomized Controlled Trials as Topic
OTO - NOTNLM
OT  - Acupuncture
OT  - Meta-analysis
OT  - Obesity
OT  - Type 2 diabetes mellitus
COIS- Declaration of competing interest The authors declare that they have no conflict 
      of interest.
EDAT- 2022/08/20 06:00
MHDA- 2022/11/19 06:00
CRDT- 2022/08/19 18:02
PHST- 2021/06/09 00:00 [received]
PHST- 2022/08/08 00:00 [revised]
PHST- 2022/08/08 00:00 [accepted]
PHST- 2022/08/20 06:00 [pubmed]
PHST- 2022/11/19 06:00 [medline]
PHST- 2022/08/19 18:02 [entrez]
AID - S1744-3881(22)00126-8 [pii]
AID - 10.1016/j.ctcp.2022.101658 [doi]
PST - ppublish
SO  - Complement Ther Clin Pract. 2022 Nov;49:101658. doi: 10.1016/j.ctcp.2022.101658. 
      Epub 2022 Aug 13.