PMID- 35987428
OWN - NLM
STAT- MEDLINE
DCOM- 20220928
LR  - 20221110
IS  - 1873-7544 (Electronic)
IS  - 0306-4522 (Linking)
VI  - 501
DP  - 2022 Oct 1
TI  - Effect of Green Tea and Tea Catechin on the Visual Motion Processing for 
      Optokinetic Responses in Mice.
PG  - 42-51
LID - S0306-4522(22)00425-0 [pii]
LID - 10.1016/j.neuroscience.2022.08.013 [doi]
AB  - In general, catechins contained in green tea are believed to have positive 
      effects on the human body and mental health. The intake of epigallocatechin 
      gallate (EGCG), a major polyphenol in green tea, is known to be effective for 
      retinal protection; however, whether green tea and/or EGCG affect visual function 
      remains unknown. In the present study, we investigated the effect of green tea 
      and EGCG on visual motion processing by measuring optokinetic responses (OKRs) in 
      young adult and aging mice. Young and aging mice (C57BL6/J) were fed a control 
      diet (control) or the test diet, which contained matcha green tea powder or green 
      tea extract (dried sencha green tea infusion), for 1 month, and their OKRs were 
      measured. They were then intraperitoneally administered saline (control) or EGCG, 
      and OKRs were measured. We found that the OKRs of young and aging mice after 
      green tea intake and after EGCG administration showed higher temporal sensitivity 
      than those of control mice. The visual ability to detect moving objects was 
      enhanced in young and aging mice upon intake of green tea or EGCG. From the above 
      results, the visual motion processing for optokinetic responses by ingesting 
      green tea was enhanced, which may be related to the effect of EGCG.
CI  - Copyright (c) 2022 IBRO. Published by Elsevier Ltd. All rights reserved.
FAU - Sugita, Yuko
AU  - Sugita Y
AD  - Laboratory for Molecular and Developmental Biology, Institute for Protein 
      Research, Osaka University, Osaka, Japan. Electronic address: 
      yuko.sugita@protein.osaka-u.ac.jp.
FAU - Furukawa, Takahisa
AU  - Furukawa T
AD  - Laboratory for Molecular and Developmental Biology, Institute for Protein 
      Research, Osaka University, Osaka, Japan. Electronic address: 
      takahisa.furukawa@protein.osaka-u.ac.jp.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220818
PL  - United States
TA  - Neuroscience
JT  - Neuroscience
JID - 7605074
RN  - 0 (Antioxidants)
RN  - 0 (Plant Extracts)
RN  - 0 (Polyphenols)
RN  - 0 (Powders)
RN  - 0 (Tea)
RN  - 8R1V1STN48 (Catechin)
RN  - BQM438CTEL (epigallocatechin gallate)
SB  - IM
EIN - Neuroscience. 2022 Oct 12;:. PMID: 36243031
MH  - Animals
MH  - Antioxidants
MH  - *Catechin/analogs & derivatives/pharmacology
MH  - Humans
MH  - Mice
MH  - Plant Extracts/pharmacology
MH  - Polyphenols
MH  - Powders
MH  - *Tea
OTO - NOTNLM
OT  - Aging
OT  - Epigallocatechin gallate
OT  - Eye movement
OT  - Green tea
OT  - Matcha
OT  - Vision
EDAT- 2022/08/21 06:00
MHDA- 2022/09/28 06:00
CRDT- 2022/08/20 19:34
PHST- 2021/12/14 00:00 [received]
PHST- 2022/08/11 00:00 [revised]
PHST- 2022/08/12 00:00 [accepted]
PHST- 2022/08/21 06:00 [pubmed]
PHST- 2022/09/28 06:00 [medline]
PHST- 2022/08/20 19:34 [entrez]
AID - S0306-4522(22)00425-0 [pii]
AID - 10.1016/j.neuroscience.2022.08.013 [doi]
PST - ppublish
SO  - Neuroscience. 2022 Oct 1;501:42-51. doi: 10.1016/j.neuroscience.2022.08.013. Epub 
      2022 Aug 18.