PMID- 35989060
OWN - NLM
STAT- MEDLINE
DCOM- 20220823
LR  - 20220922
IS  - 1558-1381 (Electronic)
IS  - 1047-9651 (Linking)
VI  - 33
IP  - 3
DP  - 2022 Aug
TI  - Environmental Medicine: Exploring the Pollutome for Solutions to Chronic 
      Diseases.
PG  - 719-732
LID - S1047-9651(22)00040-7 [pii]
LID - 10.1016/j.pmr.2022.04.010 [doi]
AB  - Environmental toxicant exposure, according to many researchers in the field, is 
      the leading cause of chronic disease and premature death globally. For the 
      purposes of this review, we will use obesity and type 2 diabetes as examples of 
      toxicant-induced chronic diseases. Endocrine Disrupting chemicals (EDCs) such as 
      phthalates and bisphenols, per- and polyfluoroalkyl substances (PFAS), and 
      persistent organic pollutants (POPs) have been linked to increased risk for 
      obesity and type 2 diabetes in both animal and large epidemiologic studies. These 
      two conditions are well-documented examples of evidence for mechanisms of both 
      adipose metabolism disruption and pancreatic cell dysfunction. The implications 
      for health care directives to both identify, prevent, and treat these exposures 
      are reviewed.
CI  - Copyright (c) 2022 Elsevier Inc. All rights reserved.
FAU - Fine, Anne Marie
AU  - Fine AM
AD  - Environmental Medicine Education International, LLC, PO Box 802, Mancos, CO 
      81328, USA. Electronic address: Dr.annemariefine@gmail.com.
FAU - Patrick, Lyn
AU  - Patrick L
AD  - Environmental Medicine Education International, LLC, PO Box 802, Mancos, CO 
      81328, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220623
PL  - United States
TA  - Phys Med Rehabil Clin N Am
JT  - Physical medicine and rehabilitation clinics of North America
JID - 9102787
RN  - 0 (Endocrine Disruptors)
SB  - IM
MH  - Animals
MH  - Chronic Disease
MH  - *Diabetes Mellitus, Type 2
MH  - *Endocrine Disruptors/toxicity
MH  - *Environmental Medicine
MH  - Humans
MH  - Obesity/chemically induced
OTO - NOTNLM
OT  - Diabetes
OT  - Endocrine-disrupting chemicals
OT  - Environmental medicine
OT  - Obesity
OT  - Pollutome
EDAT- 2022/08/22 06:00
MHDA- 2022/08/24 06:00
CRDT- 2022/08/21 21:07
PHST- 2022/08/21 21:07 [entrez]
PHST- 2022/08/22 06:00 [pubmed]
PHST- 2022/08/24 06:00 [medline]
AID - S1047-9651(22)00040-7 [pii]
AID - 10.1016/j.pmr.2022.04.010 [doi]
PST - ppublish
SO  - Phys Med Rehabil Clin N Am. 2022 Aug;33(3):719-732. doi: 
      10.1016/j.pmr.2022.04.010. Epub 2022 Jun 23.