PMID- 35990567
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220823
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 8
DP  - 2022 Aug
TI  - Atypical Location of Diffuse Large B-cell Lymphoma in the Nasal Septum.
PG  - e28085
LID - 10.7759/cureus.28085 [doi]
LID - e28085
AB  - Diffuse large B-cell lymphoma (DLBCL) is the most prevalent subtype of 
      non-Hodgkin's lymphoma (NHL). This subtype can be present in various extranodal 
      sites, including the brain, bones, intestines, kidneys, adrenal glands, and other 
      soft tissues. As demonstrated in this case, one rare site of DLBCL is the nasal 
      septum, which presents as a rapidly enlarging mass resistant to antibiotics and 
      steroids. The definitive diagnosis for this case involved biopsy, but further 
      workup, such as computed tomography (CT) and fluorescence in situ hybridization 
      (FISH), helped support the diagnosis of DLBCL. While determining the stage of the 
      lymphoma, treatment with R-CHOP chemotherapy (rituximab, cyclophosphamide, 
      doxorubicin, vincristine, and prednisone) was initiated immediately. This case 
      demonstrates a rare presentation of DLBCL in the nasal septum and describes the 
      significance of urgent examination as well as treatment.
CI  - Copyright (c) 2022, Patel et al.
FAU - Patel, Veshesh
AU  - Patel V
AD  - Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of 
      Osteopathic Medicine, Fort Lauderdale, USA.
FAU - Tacy, Collin J
AU  - Tacy CJ
AD  - Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of 
      Osteopathic Medicine, Clearwater, USA.
FAU - Creamean, Trevor
AU  - Creamean T
AD  - Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of 
      Osteopathic Medicine, Fort Lauderdale, USA.
FAU - Sibia, Adiraj
AU  - Sibia A
AD  - Department of Biology, Nova Southeastern University, Fort Lauderdale, USA.
FAU - Patel, Jayesh
AU  - Patel J
AD  - Department of Otolaryngology, McLaren Oakland Hospital, Titusville, USA.
LA  - eng
PT  - Case Reports
DEP - 20220816
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9381438
OTO - NOTNLM
OT  - airway disorders
OT  - chemo radiotherapy (chemo-rt)
OT  - large b cell lymphomas
OT  - nasal congestion
OT  - non hodgkin's lymphoma
OT  - paranasal sinus diseases
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/08/23 06:00
MHDA- 2022/08/23 06:01
PMCR- 2022/08/16
CRDT- 2022/08/22 03:56
PHST- 2022/07/26 00:00 [received]
PHST- 2022/08/16 00:00 [accepted]
PHST- 2022/08/22 03:56 [entrez]
PHST- 2022/08/23 06:00 [pubmed]
PHST- 2022/08/23 06:01 [medline]
PHST- 2022/08/16 00:00 [pmc-release]
AID - 10.7759/cureus.28085 [doi]
PST - epublish
SO  - Cureus. 2022 Aug 16;14(8):e28085. doi: 10.7759/cureus.28085. eCollection 2022 
      Aug.