PMID- 36000059
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220826
IS  - 2378-8038 (Print)
IS  - 2378-8038 (Electronic)
IS  - 2378-8038 (Linking)
VI  - 7
IP  - 4
DP  - 2022 Aug
TI  - Healthcare disparities for the development of airway stenosis from the medical 
      intensive care unit.
PG  - 1078-1086
LID - 10.1002/lio2.865 [doi]
AB  - OBJECTIVES/HYPOTHESIS: To identify sociodemographic factors associated with the 
      development of airway stenosis (AS) among intubated medical intensive care unit 
      (MICU) patients. STUDY DESIGN: Retrospective cohort study. METHODS: A 
      retrospective review of adult MICU intubated patients from 2013 to 2019 at a 
      single academic institution was performed. Univariate and multivariate analysis 
      with logistic regression examined associations between the development of AS and 
      subsite abnormalities such as posterior glottic stenosis (PGS), subglottic 
      stenosis (SGS), tracheal stenosis (TS), vocal fold immobility (VFI), and 
      posterior glottic granuloma (PGG) with age, body mass index (BMI), height, 
      weight, race, ethnicity, sex, rurality, Appalachian status, length of admission, 
      distance to hospital, and median household income. RESULTS: Of an overall sample 
      of 6603 MICU patients, 449 intubated patients were included in the study, and 204 
      patients were found to have AS. AS was statistically associated with decreased 
      driving distance to the hospital and increases in BMI. PGS was statistically 
      associated with increases in age. TS was statistically associated with increases 
      in admission duration and not having residence status in Appalachia. VFI was 
      statistically associated with decreases in driving distance to the hospital and 
      not having residence status in Appalachia. Additionally, black patients had a 
      higher odds of developing VFI compared to Caucasian patients. CONCLUSION: AS is 
      associated with sociodemographic factors such as age, BMI, shorter distance to 
      hospital, admission duration, and no Appalachian status. These data demonstrate 
      the need to further investigate the impact of social determinants of health on 
      airway pathology and outcomes. LEVEL OF EVIDENCE: 4.
CI  - (c) 2022 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley 
      Periodicals LLC on behalf of The Triological Society.
FAU - Burruss, Clayton Prakash
AU  - Burruss CP
AUID- ORCID: 0000-0003-3296-654X
AD  - College of Medicine University of Kentucky Lexington Kentucky USA.
FAU - Pappal, Robin B
AU  - Pappal RB
AD  - Department of Otolaryngology - Head and Neck Surgery University of Kentucky 
      Lexington Kentucky USA.
FAU - Witt, Michael A
AU  - Witt MA
AD  - College of Medicine University of Kentucky Lexington Kentucky USA.
FAU - Harryman, Christopher
AU  - Harryman C
AD  - College of Medicine University of Kentucky Lexington Kentucky USA.
FAU - Ali, Syed Z
AU  - Ali SZ
AD  - Department of Anesthesiology University of Kentucky Lexington Kentucky USA.
FAU - Bush, Matthew L
AU  - Bush ML
AUID- ORCID: 0000-0003-1460-5038
AD  - Department of Otolaryngology - Head and Neck Surgery University of Kentucky 
      Lexington Kentucky USA.
FAU - Fritz, Mark A
AU  - Fritz MA
AUID- ORCID: 0000-0001-6008-1533
AD  - Department of Otolaryngology - Head and Neck Surgery University of Kentucky 
      Lexington Kentucky USA.
LA  - eng
PT  - Journal Article
DEP - 20220713
PL  - United States
TA  - Laryngoscope Investig Otolaryngol
JT  - Laryngoscope investigative otolaryngology
JID - 101684963
PMC - PMC9392386
OTO - NOTNLM
OT  - airway stenosis
OT  - glottic stenosis
OT  - healthcare access
OT  - healthcare disparities
OT  - tracheal stenosis
COIS- Matthew L. Bush is a consultant for MED-EL and Stryker and has received research 
      funding from Advanced Bionics (unrelated to this research). There are no 
      conflicts of interests with the content of this manuscript. The authors have no 
      other financial relationships or conflicts of interest to disclose pertaining to 
      the manuscript. Matthew L. Bush, associate editor of the journal, had no role in 
      the editorial review of or decision to publish this article.
EDAT- 2022/08/25 06:00
MHDA- 2022/08/25 06:01
PMCR- 2022/07/13
CRDT- 2022/08/24 01:49
PHST- 2022/06/10 00:00 [received]
PHST- 2022/06/27 00:00 [revised]
PHST- 2022/06/29 00:00 [accepted]
PHST- 2022/08/24 01:49 [entrez]
PHST- 2022/08/25 06:00 [pubmed]
PHST- 2022/08/25 06:01 [medline]
PHST- 2022/07/13 00:00 [pmc-release]
AID - LIO2865 [pii]
AID - 10.1002/lio2.865 [doi]
PST - epublish
SO  - Laryngoscope Investig Otolaryngol. 2022 Jul 13;7(4):1078-1086. doi: 
      10.1002/lio2.865. eCollection 2022 Aug.