PMID- 36002855 OWN - NLM STAT- MEDLINE DCOM- 20220826 LR - 20221207 IS - 1476-511X (Electronic) IS - 1476-511X (Linking) VI - 21 IP - 1 DP - 2022 Aug 25 TI - Prevalence of dyslipidemia, treatment rate and its control among patients with type 2 diabetes mellitus in Northwest China: a cross-sectional study. PG - 77 LID - 10.1186/s12944-022-01691-1 [doi] LID - 77 AB - BACKGROUND: The prevalence of cardiovascular disease (CVD) is high in China, especially in Northwest China, and dyslipidemia in diabetes is a major factor at risk for CVD. The dyslipidemia prevalence, treatment and control among type 2 diabetes mellitus (T2DM) patients in Northwest China were investigated. METHODS: In the cross-sectional retrospective research, 1386 medical records of T2DM patients were collected from the Endocrine Department of Tangdu Hospital. And patients' age, sex, diabetes duration, glycated hemoglobin (HbA1c), complications, lipid levels, and drug use were recorded. The patient characteristics, lipid level and lipid-lowering therapy were analyzed. RESULTS: In this study, the dyslipidemia prevalence among T2DM patients was 87.7%, the treatment rate was 68.0%. The overall control rate of low-density lipoprotein cholesterol (LDL-C) was 43.1%, and control rates reached 52.7% for high-risk subjects and 36.1% for very high-risk subjects. The overall control rate of non-high-density lipoprotein cholesterol (non-HDL-C) was 19.8%. HbA1c (%) >/= 7 was indicated as a major factor predicting failure of LDL-C and non-HDL-C control [odds ratio (OR) 1.521; 2.206, 95% confidence interval (CI) 1.154-2.005; 1.583-3.076)]. CONCLUSION: Among patients with T2DM, it is high prevalence of dyslipidemia and low rate of treatment and control, and higher HbA1c level is the main factor for poor lipid control. It calls for more efforts to promote early screening, prevention and treatment of dyslipidemia for patients, thereby reducing the risk of CVD. CI - (c) 2022. The Author(s). FAU - Li, Jiahang AU - Li J AD - Department of Pharmacy, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China. FAU - Nie, Zhenxing AU - Nie Z AD - Department of Pharmacy, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China. AD - Department of Pharmacy, Hanzhong Municipal People's Hospital, Hanzhong, 723000, China. FAU - Ge, Zhongli AU - Ge Z AD - Department of Pharmacy, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China. FAU - Shi, Lei AU - Shi L AD - Department of Pharmacy, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China. FAU - Gao, Bin AU - Gao B AD - Department of Endocrinology, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China. bingao0726@163.com. FAU - Yang, Yan AU - Yang Y AD - Department of Pharmacy, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China. yangyan123@fmmu.edu.cn. LA - eng PT - Journal Article DEP - 20220825 PL - England TA - Lipids Health Dis JT - Lipids in health and disease JID - 101147696 RN - 0 (Cholesterol, LDL) RN - 0 (Glycated Hemoglobin A) SB - IM MH - *Cardiovascular Diseases/complications/epidemiology/prevention & control MH - China/epidemiology MH - Cholesterol, LDL MH - Cross-Sectional Studies MH - *Diabetes Mellitus, Type 2/complications/drug therapy/epidemiology MH - *Dyslipidemias/diagnosis/drug therapy/epidemiology MH - Glycated Hemoglobin MH - Humans MH - Prevalence MH - Retrospective Studies MH - Risk Factors PMC - PMC9404639 OTO - NOTNLM OT - Control OT - Dyslipidemia OT - Prevalence OT - Treatment OT - Type 2 diabetes mellitus COIS- The authors declare no competing interests. EDAT- 2022/08/25 06:00 MHDA- 2022/08/27 06:00 PMCR- 2022/08/25 CRDT- 2022/08/24 23:38 PHST- 2022/06/10 00:00 [received] PHST- 2022/08/18 00:00 [accepted] PHST- 2022/08/24 23:38 [entrez] PHST- 2022/08/25 06:00 [pubmed] PHST- 2022/08/27 06:00 [medline] PHST- 2022/08/25 00:00 [pmc-release] AID - 10.1186/s12944-022-01691-1 [pii] AID - 1691 [pii] AID - 10.1186/s12944-022-01691-1 [doi] PST - epublish SO - Lipids Health Dis. 2022 Aug 25;21(1):77. doi: 10.1186/s12944-022-01691-1.