PMID- 36006113 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220828 IS - 2305-6304 (Electronic) IS - 2305-6304 (Linking) VI - 10 IP - 8 DP - 2022 Jul 29 TI - Dissipation and Distribution of Prochloraz in Bananas and a Risk Assessment of Its Dietary Intake. LID - 10.3390/toxics10080435 [doi] LID - 435 AB - BACKGROUND: As a systematic fungicide, prochloraz is often used to control banana freckle disease, and it is significant to assess the safety and risk of prochloraz. METHODS: The dissipation kinetics and distribution of prochloraz in bananas were measured by high-performance liquid chromatography (HPLC). RESULTS: The results showed that the fortified recoveries in bananas were 83.01-99.12%, and the relative standard deviations (RSDs) were 2.45-7.84%. The half-life of prochloraz in banana peel (3.93-5.60 d) was significantly lower than it was in whole banana (8.25-10.80 d) and banana pulp (10.35-12.84 d). The terminal residue of prochloraz in banana fruits was below the maximum residue level (MRL, China) at pre-harvest intervals (PHI) of 21 d. Moreover, the residue of prochloraz in banana peel was always 1.06-7.71 times greater than it was in banana pulp. The dietary risk assessment results indicated that the prochloraz residue in bananas at PHI of 21 d was safe for representative populations. (4) Conclusions: We found that a 26.7% prochloraz emulsion oil in water (EW) diluted 1000-fold and sprayed three times under field conditions was safe and reliable, providing a reference for the safe application of prochloraz in bananas. FAU - Huang, Jiajian AU - Huang J AD - Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of Education, South China Agricultural University, Guangzhou 510642, China. FAU - Lin, Sukun AU - Lin S AD - Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of Education, South China Agricultural University, Guangzhou 510642, China. FAU - Zhou, Jingtong AU - Zhou J AD - Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of Education, South China Agricultural University, Guangzhou 510642, China. FAU - Chen, Huiya AU - Chen H AD - Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of Education, South China Agricultural University, Guangzhou 510642, China. FAU - Tang, Shiqi AU - Tang S AD - Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of Education, South China Agricultural University, Guangzhou 510642, China. FAU - Wu, Jian AU - Wu J AD - Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of Education, South China Agricultural University, Guangzhou 510642, China. FAU - Huang, Suqing AU - Huang S AD - College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China. FAU - Cheng, Dongmei AU - Cheng D AD - Department of Plant Protection, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China. FAU - Zhang, Zhixiang AU - Zhang Z AUID- ORCID: 0000-0002-0971-956X AD - Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of Education, South China Agricultural University, Guangzhou 510642, China. LA - eng GR - No. 2020B020224002/Key-Area Research and Development Program of Guangdong Province/ GR - No. 2020KJ122/Guangdong Provincial Special Fund for Modern Agriculture Industry Technology Innovation Teams/ PT - Journal Article DEP - 20220729 PL - Switzerland TA - Toxics JT - Toxics JID - 101639637 PMC - PMC9415821 OTO - NOTNLM OT - banana OT - dietary risk assessment OT - dissipation dynamics OT - distribution OT - high-performance liquid chromatography OT - prochloraz COIS- The authors declare no conflict of interest. EDAT- 2022/08/26 06:00 MHDA- 2022/08/26 06:01 PMCR- 2022/07/29 CRDT- 2022/08/25 10:23 PHST- 2022/06/30 00:00 [received] PHST- 2022/07/18 00:00 [revised] PHST- 2022/07/26 00:00 [accepted] PHST- 2022/08/25 10:23 [entrez] PHST- 2022/08/26 06:00 [pubmed] PHST- 2022/08/26 06:01 [medline] PHST- 2022/07/29 00:00 [pmc-release] AID - toxics10080435 [pii] AID - toxics-10-00435 [pii] AID - 10.3390/toxics10080435 [doi] PST - epublish SO - Toxics. 2022 Jul 29;10(8):435. doi: 10.3390/toxics10080435.