PMID- 36013374
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220830
IS  - 2075-1729 (Print)
IS  - 2075-1729 (Electronic)
IS  - 2075-1729 (Linking)
VI  - 12
IP  - 8
DP  - 2022 Aug 5
TI  - Benefits of Intra-Aortic Balloon Pump Support in Patients with Postcardiotomy 
      Shock Requiring Venoarterial Extracorporeal Membrane Oxygenation.
LID - 10.3390/life12081195 [doi]
LID - 1195
AB  - BACKGROUND: The benefit of the combined use of an intra-aortic balloon pump 
      (IABP) and venoarterial extracorporeal membrane oxygenation (VA-ECMO) for 
      postcardiotomy shock remains unclear. We aimed to analyse the potential benefits 
      and safety of combining these two devices. METHODS: We enrolled 200 patients 
      treated with either VA-ECMO only or in combination with IABP (ECMO-I group) 
      between January 2012 and January 2021. To adjust the patients' backgrounds, we 
      used propensity score matching for additional analyses, resulting in 57 pairs. 
      The primary endpoint was 30-day survival. Secondary endpoints included successful 
      weaning and complication rates. We also analysed hemodynamic parameters in both 
      groups. RESULTS: After propensity score matching, 30-day survival was better in 
      the ECMO-I group (log-rank p = 0.004). The ECMO-I and ECMO-only groups differed 
      regarding the secondary endpoints, including successful weaning (50.9% and 26.3%, 
      respectively; p = 0.012) and the need for continuous renal replacement therapy 
      (28.1% and 50.9%, p = 0.021). Complication rates were not statistically different 
      between the two groups. CONCLUSION: Compared to VA-ECMO alone, the combined use 
      of VA-ECMO and IABP is beneficial regarding 30-day survival in selected patients 
      with postcardiotomy shock; successful ECMO weaning and freedom from renal 
      replacement therapy is more common in patients supported with VA-ECMO plus IABP.
FAU - Radakovic, Dejan
AU  - Radakovic D
AUID- ORCID: 0000-0002-5428-2029
AD  - Department of Thoracic and Cardiovascular Surgery, University Hospital Wurzburg, 
      97080 Wurzburg, Germany.
FAU - Penov, Kiril
AU  - Penov K
AD  - Department of Thoracic and Cardiovascular Surgery, University Hospital Wurzburg, 
      97080 Wurzburg, Germany.
FAU - Hamouda, Khaled
AU  - Hamouda K
AD  - Department of Thoracic and Cardiovascular Surgery, University Hospital Wurzburg, 
      97080 Wurzburg, Germany.
FAU - Madrahimov, Nodir
AU  - Madrahimov N
AD  - Department of Thoracic and Cardiovascular Surgery, University Hospital Wurzburg, 
      97080 Wurzburg, Germany.
FAU - Radakovic, Darko
AU  - Radakovic D
AUID- ORCID: 0000-0002-3380-0747
AD  - Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, 
      Ruhr-University Bochum, 32545 Bad Oeynhausen, Germany.
FAU - Bening, Constanze
AU  - Bening C
AD  - Department of Thoracic and Cardiovascular Surgery, University Hospital Wurzburg, 
      97080 Wurzburg, Germany.
FAU - Leyh, Rainer G
AU  - Leyh RG
AD  - Department of Thoracic and Cardiovascular Surgery, University Hospital Wurzburg, 
      97080 Wurzburg, Germany.
FAU - Aleksic, Ivan
AU  - Aleksic I
AD  - Department of Thoracic and Cardiovascular Surgery, University Hospital Wurzburg, 
      97080 Wurzburg, Germany.
LA  - eng
PT  - Journal Article
DEP - 20220805
PL  - Switzerland
TA  - Life (Basel)
JT  - Life (Basel, Switzerland)
JID - 101580444
PMC - PMC9409933
OTO - NOTNLM
OT  - IABP
OT  - VA-ECMO
OT  - postcardiotomy shock
COIS- The authors declare no conflict of interest.
EDAT- 2022/08/27 06:00
MHDA- 2022/08/27 06:01
PMCR- 2022/08/05
CRDT- 2022/08/26 01:29
PHST- 2022/07/06 00:00 [received]
PHST- 2022/07/31 00:00 [revised]
PHST- 2022/08/03 00:00 [accepted]
PHST- 2022/08/26 01:29 [entrez]
PHST- 2022/08/27 06:00 [pubmed]
PHST- 2022/08/27 06:01 [medline]
PHST- 2022/08/05 00:00 [pmc-release]
AID - life12081195 [pii]
AID - life-12-01195 [pii]
AID - 10.3390/life12081195 [doi]
PST - epublish
SO  - Life (Basel). 2022 Aug 5;12(8):1195. doi: 10.3390/life12081195.