PMID- 36029231
OWN - NLM
STAT- MEDLINE
DCOM- 20230321
LR  - 20230321
IS  - 1550-9613 (Electronic)
IS  - 0278-4297 (Linking)
VI  - 42
IP  - 4
DP  - 2023 Apr
TI  - Clinical Characteristics of Patients With Surgically Resected Pancreatic Cysts: A 
      Retrospective Analysis of 136 Patients.
PG  - 901-913
LID - 10.1002/jum.16085 [doi]
AB  - OBJECTIVES: To retrospectively analyze the characteristics of pancreatic cysts 
      with respect to histopathological diagnosis and various diagnostic imaging tools. 
      METHODS: The clinical features of 136 patients and characteristics of 
      histopathologically diagnosed cysts were retrospectively assessed. The diagnostic 
      accuracy of endoscopic ultrasound (EUS), computed tomography (CT), and magnetic 
      resonance imaging (MRI) for pancreatic cysts was compared. Risk factors for 
      high-grade dysplasia/invasive cancer in patients with intraductal papillary 
      mucinous neoplasms (IPMNs) were also determined. RESULTS: The final analysis 
      included 30 serous cystic neoplasms (SCNs) (21.6%), 13 mucinous cystic neoplasms 
      (MCNs) (9.4%), 65 IPMNs (46.8%), and 13 solid pseudopapillary neoplasms (SPNs) 
      (9.4%). The percentage of women with MCNs, SPNs, SCNs, and IPMNs was 100.0, 76.9, 
      73.3, and 47.7%, respectively (P < .001). The percentages of patients over 
      60 years of age with IPMNs, SCNs, MCNs, and SPNs were 73.9, 23.3, 0, and 0%, 
      respectively (P < .001). The percentage of cysts located in the body and tail of 
      the pancreas in MCNs, SCNs, SPNs, and IPMNs was 100, 70, 53.9, and 46.2%, 
      respectively (P < .001). A unique honeycomb appearance was observed in 26.7% of 
      SCNs. The overall diagnostic accuracy of EUS, CT, and MRI for pancreatic cysts 
      was 82.6, 72.5, and 73.9%, respectively. Lesion size and presence of solid 
      components were independent predictors of high-risk IPMNs. CONCLUSIONS: Patient 
      characteristics and cyst features can help to differentiate pancreatic cyst types 
      and identify high-risk IPMNs. The diagnostic accuracy of EUS for pancreatic cysts 
      is superior to that of CT and MRI.
CI  - (c) 2022 American Institute of Ultrasound in Medicine.
FAU - Gong, Ting-Ting
AU  - Gong TT
AD  - Department of Gastroenterology, Ruijin Hospital, School of Medicine, Shanghai 
      Jiao Tong University, Shanghai, China.
FAU - Wang, Wei
AU  - Wang W
AUID- ORCID: 0000-0001-7868-7891
AD  - Department of General Surgery and Research Institute of Pancreatic Diseases, 
      Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20220827
PL  - England
TA  - J Ultrasound Med
JT  - Journal of ultrasound in medicine : official journal of the American Institute of 
      Ultrasound in Medicine
JID - 8211547
SB  - IM
MH  - Humans
MH  - Female
MH  - Middle Aged
MH  - Aged
MH  - Retrospective Studies
MH  - *Neoplasms, Cystic, Mucinous, and Serous
MH  - *Pancreatic Neoplasms/diagnostic imaging/surgery
MH  - *Pancreatic Cyst/diagnostic imaging/surgery/pathology
MH  - *Carcinoma, Pancreatic Ductal/pathology
OTO - NOTNLM
OT  - intraductal papillary mucinous neoplasms
OT  - mucinous cystic neoplasms
OT  - pancreatic cysts
OT  - serous cystic neoplasms
OT  - solid pseudopapillary neoplasms
EDAT- 2022/08/28 06:00
MHDA- 2023/03/22 06:00
CRDT- 2022/08/27 08:42
PHST- 2022/08/02 00:00 [revised]
PHST- 2022/06/09 00:00 [received]
PHST- 2022/08/07 00:00 [accepted]
PHST- 2022/08/28 06:00 [pubmed]
PHST- 2023/03/22 06:00 [medline]
PHST- 2022/08/27 08:42 [entrez]
AID - 10.1002/jum.16085 [doi]
PST - ppublish
SO  - J Ultrasound Med. 2023 Apr;42(4):901-913. doi: 10.1002/jum.16085. Epub 2022 Aug 
      27.