PMID- 36030043
OWN - NLM
STAT- MEDLINE
DCOM- 20221216
LR  - 20221221
IS  - 1873-1597 (Electronic)
IS  - 1572-1000 (Linking)
VI  - 40
DP  - 2022 Dec
TI  - Modified photodynamic therapy of vulvar giant condyloma acuminatum complicated by 
      systemic lupus erythematosus: A case report.
PG  - 103089
LID - S1572-1000(22)00375-1 [pii]
LID - 10.1016/j.pdpdt.2022.103089 [doi]
AB  - Giant condyloma acuminatum (GCA) is a rare disease characterized by 
      cauliflower-like tumors in the genital area, with a peculiar smell, bleeding, and 
      local infection. Its occurrence is related to a variety of risk factors, such as 
      human papillomavirus infection, immune deficiency, poor sanitary conditions, 
      multiple sexual partners, and chronic genital infection. Surgical resection is 
      still the preferred treatment for the disease. This paper reports that a patient 
      with GCA complicated by systemic lupus erythematosus (SLE) and persistent 
      thrombocytopenia who could not be treated surgically was treated with modified 
      photodynamic therapy (M-PDT) in our outpatient department. After several 
      treatments, the pain, odor, and secretion on the surface of the wart were 
      significantly reduced, although the size of the wart was not significantly 
      improved. Unfortunately, the patient died subsequently due to the aggravation of 
      SLE. However, clinical treatment with M-PDT may be used as a palliative treatment 
      when similar patients are encountered.
CI  - Copyright (c) 2022 Elsevier B.V. All rights reserved.
FAU - Zhang, Yunfeng
AU  - Zhang Y
AD  - Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University 
      School of Medicine, 1278 Baode Road, Shanghai 200443, PR China.
FAU - Zhang, Linglin
AU  - Zhang L
AD  - Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University 
      School of Medicine, 1278 Baode Road, Shanghai 200443, PR China.
FAU - Zhang, Haiyan
AU  - Zhang H
AD  - Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University 
      School of Medicine, 1278 Baode Road, Shanghai 200443, PR China.
FAU - Zhang, Guolong
AU  - Zhang G
AD  - Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University 
      School of Medicine, 1278 Baode Road, Shanghai 200443, PR China.
FAU - Zhou, Zhongxia
AU  - Zhou Z
AD  - Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University 
      School of Medicine, 1278 Baode Road, Shanghai 200443, PR China.
FAU - Zhao, Yan
AU  - Zhao Y
AD  - Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University 
      School of Medicine, 1278 Baode Road, Shanghai 200443, PR China.
FAU - Zhu, Shaojian
AU  - Zhu S
AD  - Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University 
      School of Medicine, 1278 Baode Road, Shanghai 200443, PR China.
FAU - Wang, Xiuli
AU  - Wang X
AD  - Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University 
      School of Medicine, 1278 Baode Road, Shanghai 200443, PR China. Electronic 
      address: wangxiuli_1400023@tongji.edu.cn.
LA  - eng
PT  - Case Reports
DEP - 20220825
PL  - Netherlands
TA  - Photodiagnosis Photodyn Ther
JT  - Photodiagnosis and photodynamic therapy
JID - 101226123
SB  - IM
MH  - Humans
MH  - *Photochemotherapy/methods
MH  - *Buschke-Lowenstein Tumor/complications/drug therapy
MH  - *Condylomata Acuminata/complications/drug therapy/surgery
MH  - *Papillomavirus Infections/drug therapy
MH  - *Lupus Erythematosus, Systemic/complications/drug therapy
OTO - NOTNLM
OT  - Photodynamic therapy
OT  - Systemic lupus erythematosus
OT  - Vulvar giant condyloma acuminatum
COIS- Declaration of Competing Interest None.
EDAT- 2022/08/28 06:00
MHDA- 2022/12/15 06:00
CRDT- 2022/08/27 19:32
PHST- 2022/04/23 00:00 [received]
PHST- 2022/08/23 00:00 [revised]
PHST- 2022/08/23 00:00 [accepted]
PHST- 2022/08/28 06:00 [pubmed]
PHST- 2022/12/15 06:00 [medline]
PHST- 2022/08/27 19:32 [entrez]
AID - S1572-1000(22)00375-1 [pii]
AID - 10.1016/j.pdpdt.2022.103089 [doi]
PST - ppublish
SO  - Photodiagnosis Photodyn Ther. 2022 Dec;40:103089. doi: 
      10.1016/j.pdpdt.2022.103089. Epub 2022 Aug 25.