PMID- 36034396 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220830 IS - 2296-875X (Print) IS - 2296-875X (Electronic) IS - 2296-875X (Linking) VI - 9 DP - 2022 TI - Non-Intubated Thoracic Surgery: Standpoints and Perspectives. PG - 937633 LID - 10.3389/fsurg.2022.937633 [doi] LID - 937633 AB - Non-intubated video-assisted thoracic surgery (NI-VATS) combines the advantages of a non-intubated surgery with the benefits of a minimally invasive approach. First, NI-VATS is performed in the case of fragile patients when general anesthesia and/or orotracheal intubation can be foreseen as inconvenient. However, NI-VATS indications have been increasingly extended to different patient conditions, considering the increasingly assessed safety and feasibility of the procedure. Currently, the NI-VATS approach is used worldwide for different thoracic surgery procedures, including the management of malignant pleural effusion, surgical treatment of empyema, anatomical and non-anatomical lung resection, and other indications. In fact, this approach has shown to be less impactful than VATS under general anesthesia, allowing for shortened hospitalization and faster recovery after surgery. Besides, NI-VATS is associated with fewer pulmonary complications, less respiratory distress, and a mild systemic inflammatory reaction. For these reasons, this approach should be considered not only in patients with poor cardiac or respiratory function (general functional reserve), but also in other eligible conditions. We explored the anesthetic and surgical aspects of such an approach, including the management of analgesia, cough reflex, depth of sedation, and intraoperative technical issues to put this approach in perspective. CI - Copyright (c) 2022 Anile, Vannucci, Ferrante, Bruno, De Paolo, Bassi, Pugliese, Venuta and the NIVATS interest group. FAU - Anile, Marco AU - Anile M AD - Department of Thoracic Surgery and Lung Transplantation, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. FAU - Vannucci, Jacopo AU - Vannucci J AD - Department of Thoracic Surgery and Lung Transplantation, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. FAU - Ferrante, Francesco AU - Ferrante F AD - Department of Thoracic Surgery and Lung Transplantation, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. FAU - Bruno, Katia AU - Bruno K AD - Department of Anesthesiology and Critical Care, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. FAU - De Paolo, Dalila AU - De Paolo D AD - Department of Anesthesiology and Critical Care, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. FAU - Bassi, Massimiliano AU - Bassi M AD - Department of Thoracic Surgery and Lung Transplantation, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. FAU - Pugliese, Francesco AU - Pugliese F AD - Department of Anesthesiology and Critical Care, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. FAU - Venuta, Federico AU - Venuta F AD - Department of Thoracic Surgery and Lung Transplantation, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy. CN - NIVATS Interest Group LA - eng PT - Journal Article DEP - 20220701 PL - Switzerland TA - Front Surg JT - Frontiers in surgery JID - 101645127 PMC - PMC9407015 OTO - NOTNLM OT - NI-VATS OT - Non-intubated surgery OT - anesthesia OT - perioperative management OT - pulmonary resections OT - video-assisted thoracic surgery COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2022/08/30 06:00 MHDA- 2022/08/30 06:01 PMCR- 2022/07/01 CRDT- 2022/08/29 05:07 PHST- 2022/05/06 00:00 [received] PHST- 2022/06/09 00:00 [accepted] PHST- 2022/08/29 05:07 [entrez] PHST- 2022/08/30 06:00 [pubmed] PHST- 2022/08/30 06:01 [medline] PHST- 2022/07/01 00:00 [pmc-release] AID - 10.3389/fsurg.2022.937633 [doi] PST - epublish SO - Front Surg. 2022 Jul 1;9:937633. doi: 10.3389/fsurg.2022.937633. eCollection 2022.