PMID- 36035654
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220830
IS  - 2251-7251 (Print)
IS  - 2251-726X (Electronic)
IS  - 2251-7251 (Linking)
VI  - 34
IP  - 123
DP  - 2022 Jul
TI  - Prognostication of Sino-Nasal Mucormycosis.
PG  - 157-164
LID - 10.22038/IJORL.2022.58523.3021 [doi]
AB  - INTRODUCTION: For the purpose of prognostication of sinonasal mucormycosis, a 
      detailed analysis of the clinical, diagnostic, therapeutic and outcome parameters 
      has been contemplated. MATERIALS AND METHODS: Retrospectively data was collected 
      for all patients of sinonasal mucormycosis managed in a tertiary care hospital in 
      last 5years. RESULTS: Diabetes was the commonest comorbidity among total of 52 
      cases. Disease extent-wise, 16, 23 and 13 patients had sino-nasal (SN), 
      rhino-orbital (RO) and rhino-orbito-cerebral (ROC) mucormycosis respectively. 
      Median cumulative Amphotericin-B administered was 3.5gms and 94.2% of cases 
      underwent surgical debridement depending on the disease extent. With a median 
      follow-up of 18months, 67% of the patients are alive and disease free, 2% are 
      under treatment and 29% of patients have expired. The mortality rate was 12.5% in 
      SN, 30.5% in RO and 38.5% in ROC mucormycosis. Palatal and orbital involvement is 
      associated with statistically significant mortality risk at one month. 
      CONCLUSIONS: Mortality rate in sino-nasal mucormycosis can be significantly 
      curtailed with prompt control of underlying comorbidity, aggressive medical and 
      adequate surgical management.
FAU - Sagar, Prem
AU  - Sagar P
AD  - Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical 
      Sciences, New Delhi, India.
FAU - Mehmi, Namrita
AU  - Mehmi N
AD  - Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical 
      Sciences, New Delhi, India.
FAU - Kanodia, Anupam
AU  - Kanodia A
AD  - Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical 
      Sciences, New Delhi, India.
FAU - Jaiswal, Avinash Shekhar
AU  - Jaiswal AS
AD  - Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical 
      Sciences, New Delhi, India.
FAU - Kumar, Rajeev
AU  - Kumar R
AD  - Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical 
      Sciences, New Delhi, India.
FAU - Singh, Chirom Amit
AU  - Singh CA
AD  - Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical 
      Sciences, New Delhi, India.
FAU - Kumar, Rakesh
AU  - Kumar R
AD  - Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical 
      Sciences, New Delhi, India.
FAU - Thakar, Alok
AU  - Thakar A
AD  - Department of Otolaryngology & Head Neck Surgery, All India Institute of Medical 
      Sciences, New Delhi, India.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Iran J Otorhinolaryngol
JT  - Iranian journal of otorhinolaryngology
JID - 101577699
PMC - PMC9392998
OTO - NOTNLM
OT  - Amphotericin
OT  - Diabetes
OT  - Mucormycosis
OT  - Orbital mucormycosis
OT  - Sino nasal Mucormycosis
EDAT- 2022/08/30 06:00
MHDA- 2022/08/30 06:01
PMCR- 2022/07/01
CRDT- 2022/08/29 05:28
PHST- 2021/07/06 00:00 [received]
PHST- 2022/06/09 00:00 [accepted]
PHST- 2022/08/29 05:28 [entrez]
PHST- 2022/08/30 06:00 [pubmed]
PHST- 2022/08/30 06:01 [medline]
PHST- 2022/07/01 00:00 [pmc-release]
AID - 10.22038/IJORL.2022.58523.3021 [doi]
PST - ppublish
SO  - Iran J Otorhinolaryngol. 2022 Jul;34(123):157-164. doi: 
      10.22038/IJORL.2022.58523.3021.