PMID- 36040457
OWN - NLM
STAT- MEDLINE
DCOM- 20221011
LR  - 20221011
IS  - 1540-8191 (Electronic)
IS  - 0886-0440 (Linking)
VI  - 37
IP  - 11
DP  - 2022 Nov
TI  - Hypo-attenuated leaflet thickening after Perceval sutureless bioprosthesis 
      implantation.
PG  - 3928-3931
LID - 10.1111/jocs.16858 [doi]
AB  - Modern multi-slice computed tomography (CT) has increased the detection of 
      hypo-attenuated leaflet thickening (HALT). Furthermore, HALT's impact on 
      transcatheter or surgical biological aortic valve (AV) prostheses has attracted 
      attention. However, few reports on HALT in sutureless bioprostheses exist. 
      Herein, we report a case of early structural valve deterioration due to HALT 
      after AV replacement (AVR) with a Perceval bioprosthesis, which improved after 
      anticoagulation therapy. A 79-year-old man admitted to our hospital with 
      paroxysmal atrial fibrillation (PAF) during hemodialysis was also diagnosed with 
      AV stenosis and, coronary artery disease, and PAF. He underwent AVR, coronary 
      artery bypass grafting, and left atrial appendage resection. Although the 
      postoperative course was uneventful with dual antiplatelet therapy, postoperative 
      enhanced CT revealed HALT with reduced leaflet motion, and echocardiography 
      showed an increased transvalvular pressure gradient. After using warfarin with 
      target prothrombin time-international normalized ratio of 2-2.5 and/or heparin 
      with target activated partial thromboplastin time of 45-60 s, the HALT 
      disappeared with an improved transvalvular pressure gradient without any 
      thromboembolic events.
CI  - (c) 2022 Wiley Periodicals LLC.
FAU - Kono, Takanori
AU  - Kono T
AUID- ORCID: 0000-0001-7984-8706
AD  - Division of Cardiovascular Surgery, Department of Surgery, Kurume University 
      School of Medicine, Kurume City, Fukuoka, Japan.
FAU - Takaseya, Tohru
AU  - Takaseya T
AD  - Division of Cardiovascular Surgery, Department of Surgery, Kurume University 
      School of Medicine, Kurume City, Fukuoka, Japan.
FAU - Takagi, Kazuyoshi
AU  - Takagi K
AUID- ORCID: 0000-0002-4384-8218
AD  - Division of Cardiovascular Surgery, Department of Surgery, Kurume University 
      School of Medicine, Kurume City, Fukuoka, Japan.
FAU - Tayama, Eiki
AU  - Tayama E
AD  - Division of Cardiovascular Surgery, Department of Surgery, Kurume University 
      School of Medicine, Kurume City, Fukuoka, Japan.
LA  - eng
PT  - Case Reports
DEP - 20220830
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
RN  - 0 (Anticoagulants)
RN  - 0 (Platelet Aggregation Inhibitors)
RN  - 5Q7ZVV76EI (Warfarin)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Aged
MH  - Anticoagulants/therapeutic use
MH  - Aortic Valve/surgery
MH  - *Aortic Valve Stenosis/diagnostic imaging/surgery
MH  - *Bioprosthesis/adverse effects
MH  - *Heart Valve Prosthesis/adverse effects
MH  - *Heart Valve Prosthesis Implantation/methods
MH  - Heparin
MH  - Humans
MH  - Male
MH  - Platelet Aggregation Inhibitors
MH  - Prosthesis Design
MH  - *Transcatheter Aortic Valve Replacement
MH  - Treatment Outcome
MH  - Warfarin
OTO - NOTNLM
OT  - Perceval bioprosthesis
OT  - aortic valve replacement
OT  - hypo-attenuated leaflet thickening
OT  - sutureless valve
EDAT- 2022/08/31 06:00
MHDA- 2022/10/12 06:00
CRDT- 2022/08/30 11:08
PHST- 2022/07/23 00:00 [revised]
PHST- 2022/07/05 00:00 [received]
PHST- 2022/07/29 00:00 [accepted]
PHST- 2022/08/31 06:00 [pubmed]
PHST- 2022/10/12 06:00 [medline]
PHST- 2022/08/30 11:08 [entrez]
AID - 10.1111/jocs.16858 [doi]
PST - ppublish
SO  - J Card Surg. 2022 Nov;37(11):3928-3931. doi: 10.1111/jocs.16858. Epub 2022 Aug 
      30.