PMID- 36046499
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220907
IS  - 1177-889X (Print)
IS  - 1177-889X (Electronic)
IS  - 1177-889X (Linking)
VI  - 16
DP  - 2022
TI  - Preferences for Patients with Type 2 Diabetes Mellitus for Medications in 
      Shandong Province, China: A Discrete Choice Experiment.
PG  - 2335-2344
LID - 10.2147/PPA.S367985 [doi]
AB  - PURPOSE: To evaluate preferences for medications among patients with type 2 
      diabetes mellitus (T2DM) from urban community health stations or rural village 
      clinics in Shandong province, China. METHODS: We use a discrete choice experiment 
      (DCE) to measure the medication preferences. Each patient completed six DCE 
      choice sets. The attributes for the DCE questionnaire include mode of 
      administration, out-of-pocket medication cost per month, fasting blood glucose 
      control effect and frequency of hypoglycemia events. The conditional logit model 
      (Clogit) and mixed logit model (MXL) were used to evaluate choice data. RESULTS: 
      A total of 887 patients with T2DM completed the survey. The mean age of 
      participants was 64 years, 36.42% experienced complications, and the mean 
      duration of diabetes was about 8 years. Overall, patients' ideal medication would 
      not have hypoglycemia events, provide normal fasting glucose levels, have oral 
      medication three times a day and lower monthly medication cost. Patients 
      prioritized the frequency of hypoglycemia events (beta=15.055, P < 0.01) and were 
      willing to spend CNY 393.10 per month to avoid hypoglycemia events. For patients 
      with higher educational levels and with longer diagnosis time, the effect of 
      fasting blood glucose was more relevant than all other outcomes. CONCLUSION: This 
      study provides information on T2DM patients' preference for medications. Our 
      results suggest that clinical doctors should present patients with a variety of 
      pharmaceutical characteristics and include their preference into medication 
      decision, which will improve patient adherence and health outcomes.
CI  - (c) 2022 Lv et al.
FAU - Lv, Yuyu
AU  - Lv Y
AUID- ORCID: 0000-0003-1275-5446
AD  - Center for Health Management and Policy Research, School of Public Health, 
      Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of 
      China.
AD  - NHC Key Laboratory of Health Economics and Policy Research (Shandong University), 
      Jinan, People's Republic of China.
FAU - Ren, Ru
AU  - Ren R
AD  - Center for Health Management and Policy Research, School of Public Health, 
      Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of 
      China.
AD  - NHC Key Laboratory of Health Economics and Policy Research (Shandong University), 
      Jinan, People's Republic of China.
AD  - Center for Health Preference Research, Shandong University, Jinan, People's 
      Republic of China.
FAU - Tang, Chengxiang
AU  - Tang C
AD  - Macquarie University Centre for the Health Economy, Macquarie University Business 
      School & Australian Institute of Health Innovation, Macquarie University, Sydney, 
      NSW, Australia.
FAU - Song, Kuimeng
AU  - Song K
AD  - School of Health Care Security, Shandong First Medical University & Shandong 
      Academy of Medical Sciences, Jinan, People's Republic of China.
FAU - Li, Shunping
AU  - Li S
AUID- ORCID: 0000-0001-8144-6220
AD  - Center for Health Management and Policy Research, School of Public Health, 
      Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of 
      China.
AD  - NHC Key Laboratory of Health Economics and Policy Research (Shandong University), 
      Jinan, People's Republic of China.
AD  - Center for Health Preference Research, Shandong University, Jinan, People's 
      Republic of China.
FAU - Wang, Haipeng
AU  - Wang H
AUID- ORCID: 0000-0002-1315-3474
AD  - Center for Health Management and Policy Research, School of Public Health, 
      Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of 
      China.
AD  - NHC Key Laboratory of Health Economics and Policy Research (Shandong University), 
      Jinan, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20220825
PL  - New Zealand
TA  - Patient Prefer Adherence
JT  - Patient preference and adherence
JID - 101475748
PMC - PMC9423121
OTO - NOTNLM
OT  - discrete choice experiment
OT  - medication
OT  - patients' preference
OT  - type 2 diabetes mellitus
COIS- The authors report no conflicts of interest in this work.
EDAT- 2022/09/02 06:00
MHDA- 2022/09/02 06:01
PMCR- 2022/08/25
CRDT- 2022/09/01 02:30
PHST- 2022/03/31 00:00 [received]
PHST- 2022/08/10 00:00 [accepted]
PHST- 2022/09/01 02:30 [entrez]
PHST- 2022/09/02 06:00 [pubmed]
PHST- 2022/09/02 06:01 [medline]
PHST- 2022/08/25 00:00 [pmc-release]
AID - 367985 [pii]
AID - 10.2147/PPA.S367985 [doi]
PST - epublish
SO  - Patient Prefer Adherence. 2022 Aug 25;16:2335-2344. doi: 10.2147/PPA.S367985. 
      eCollection 2022.