PMID- 36047956
OWN - NLM
STAT- MEDLINE
DCOM- 20221228
LR  - 20230629
IS  - 2156-5376 (Electronic)
IS  - 2161-8313 (Print)
IS  - 2161-8313 (Linking)
VI  - 13
IP  - 6
DP  - 2022 Dec 22
TI  - Consumption of Dairy Products and the Risk of Overweight or Obesity, 
      Hypertension, and Type 2 Diabetes Mellitus: A Dose-Response Meta-Analysis and 
      Systematic Review of Cohort Studies.
PG  - 2165-2179
LID - 10.1093/advances/nmac096 [doi]
AB  - Dairy products have been suggested to be related to the prevention of overweight 
      or obesity, hypertension, and type 2 diabetes mellitus (T2DM). These associations 
      are currently controversial, however, and a systematic quantitative meta-analysis 
      is lacking. In this study, we examined the associations between dairy products 
      and the risk of overweight or obesity, hypertension, and T2DM and tested for 
      dose-response relations. We comprehensively searched PubMed, Embase, and Web of 
      Science up to April 2021. Cohort studies were included if dairy food consumption 
      was reported at a minimum of 3 levels or as continuous variables, and the 
      associations were assessed with overweight or obesity, hypertension, and T2DM. 
      Summary RRs and 95% CIs were estimated for the dose-response association. 
      Restricted cubic splines were used to evaluate the linear or nonlinear relations. 
      Among the 9887 articles retrieved, 42 articles were included. For overweight or 
      obesity, a linear association was observed for total dairy, milk, and yogurt. The 
      risk decreased by 25%, 7%, and 12% per 200-g/d increase for total dairy, high-fat 
      dairy, and milk, respectively, and by 13% per 50-g/d increment of yogurt. For 
      hypertension, a nonlinear association was observed with total dairy, whereas 
      significant inverse associations were found for low-fat dairy (RR: 0.94; 95% CI: 
      0.90, 0.98) and milk (RR: 0.94; 95% CI: 0.92, 0.97) per 200-g/d intake increase. 
      For T2DM, all types of dairy food consumption except for milk and low-fat dairy 
      products showed nonlinear associations, with total dairy and yogurt intake 
      associated with 3% and 7% lower risk per 200-g/d and 50-g/d intake increase, 
      respectively. In conclusion, our study suggests that total dairy is associated 
      with a low risk of overweight or obesity, hypertension, and T2DM, especially milk 
      and yogurt for overweight or obesity, low-fat dairy and milk for hypertension, 
      and yogurt for T2DM.
CI  - (c) The Author(s) 2022. Published by Oxford University Press on behalf of the 
      American Society for Nutrition.
FAU - Feng, Yifei
AU  - Feng Y
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Zhao, Yang
AU  - Zhao Y
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Liu, Jiong
AU  - Liu J
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Huang, Zelin
AU  - Huang Z
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Yang, Xingjin
AU  - Yang X
AD  - Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou 
      University, Zhengzhou, Henan, People's Republic of China.
FAU - Qin, Pei
AU  - Qin P
AD  - Department of Medical Record Management, Shenzhen Qianhai Shekou Free Trade Zone 
      Hospital, Shenzhen, Guangdong, People's Republic of China.
FAU - Chen, Chuanqi
AU  - Chen C
AD  - Department of Endocrinology, Shenzhen Qianhai Shekou Free Trade Zone Hospital, 
      Shenzhen, Guangdong, People's Republic of China.
FAU - Luo, Xinping
AU  - Luo X
AD  - Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Li, Yang
AU  - Li Y
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Wu, Yuying
AU  - Wu Y
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Li, Xi
AU  - Li X
AD  - Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou 
      University, Zhengzhou, Henan, People's Republic of China.
FAU - Huang, Hao
AU  - Huang H
AD  - Department of General Practice, The Affiliated Luohu Hospital of Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Hu, Fulan
AU  - Hu F
AUID- ORCID: 0000-0002-2386-1503
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Hu, Dongsheng
AU  - Hu D
AUID- ORCID: 0000-0002-9998-8041
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
AD  - Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou 
      University, Zhengzhou, Henan, People's Republic of China.
AD  - Department of General Practice, The Affiliated Luohu Hospital of Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Liu, Yu
AU  - Liu Y
AD  - Department of General Practice, The Affiliated Luohu Hospital of Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
FAU - Zhang, Ming
AU  - Zhang M
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen 
      University Health Science Center, Shenzhen, Guangdong, People's Republic of 
      China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Systematic Review
PL  - United States
TA  - Adv Nutr
JT  - Advances in nutrition (Bethesda, Md.)
JID - 101540874
SB  - IM
MH  - Animals
MH  - Humans
MH  - Cohort Studies
MH  - Dairy Products
MH  - *Diabetes Mellitus, Type 2/epidemiology/etiology/prevention & control
MH  - Diet
MH  - *Hypertension/epidemiology/etiology
MH  - Milk
MH  - Obesity/epidemiology/etiology
MH  - Overweight/etiology
MH  - Risk Factors
PMC - PMC9776648
OTO - NOTNLM
OT  - cohort studies
OT  - dairy
OT  - hypertension
OT  - meta-analysis
OT  - overweight/obesity
OT  - type 2 diabetes mellitus
EDAT- 2022/09/02 06:00
MHDA- 2022/12/27 06:00
PMCR- 2022/09/01
CRDT- 2022/09/01 10:06
PHST- 2022/05/17 00:00 [received]
PHST- 2022/07/12 00:00 [revised]
PHST- 2022/08/30 00:00 [accepted]
PHST- 2022/09/02 06:00 [pubmed]
PHST- 2022/12/27 06:00 [medline]
PHST- 2022/09/01 10:06 [entrez]
PHST- 2022/09/01 00:00 [pmc-release]
AID - S2161-8313(23)00070-4 [pii]
AID - nmac096 [pii]
AID - 10.1093/advances/nmac096 [doi]
PST - ppublish
SO  - Adv Nutr. 2022 Dec 22;13(6):2165-2179. doi: 10.1093/advances/nmac096.