PMID- 3604929
OWN - NLM
STAT- MEDLINE
DCOM- 19870803
LR  - 20190622
IS  - 0002-9149 (Print)
IS  - 0002-9149 (Linking)
VI  - 60
IP  - 1
DP  - 1987 Jul 1
TI  - Usefulness of residual ischemic myocardium within prior infarct zone for 
      identifying patients at high risk late after acute myocardial infarction.
PG  - 15-9
AB  - This study examines the prognostic implications of ischemia within the territory 
      of a prior acute myocardial infarction (AMI) vs ischemia at a distance, which 
      develops late after AMI. Sixty-one consecutive patients who underwent both 
      exercise thallium-201 (TI-201) imaging and cardiac catheterization for evaluation 
      of chest pain that developed after discharge from the hospital for AMI form the 
      study group. Mean interval between infarction to the TI-201 study was 10 +/- 17 
      months. Initial and 2-hour delay TI-201 images were analyzed quantitatively to 
      determine the presence and location (within vs outside the prior infarct zone) of 
      TI-201 redistribution, a marker of ischemic viable myocardium. TI-201 imaging 
      results were separated into 3 groups based on presence and location of TI-201 
      redistribution: no significant TI-201 redistribution was found in 16 patients; in 
      29, TI-201 redistribution was confined to the infarct zone; and in 16, TI-201 
      redistribution was outside the infarct zone. Stepwise multivariate logistic 
      regression analysis was used to examine the comparative ability of TI-201 results 
      and other patient variables to predict cardiac events. For total cardiac events 
      (cardiac death, recurrent nonfatal AMI, unstable angina and coronary 
      revascularization), both the presence of any TI-201 redistribution and 
      multivessel angiographic coronary artery disease were significant predictors. 
      However, when coronary revascularization was excluded as an endpoint, TI-201 
      redistribution limited to the prior infarct zone was the only significant 
      predictor of cardiac events. All 8 cardiac events occurred in patients with 
      T1-201 redistribution limited to the infart zone.(ABSTRACT TRUNCATED AT 250 
      WORDS)
FAU - Brown, K A
AU  - Brown KA
FAU - Weiss, R M
AU  - Weiss RM
FAU - Clements, J P
AU  - Clements JP
FAU - Wackers, F J
AU  - Wackers FJ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - 0 (Radioisotopes)
RN  - AD84R52XLF (Thallium)
SB  - IM
MH  - Adult
MH  - Coronary Angiography
MH  - Coronary Disease/*diagnosis/pathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis/pathology
MH  - Myocardium/*pathology
MH  - Prognosis
MH  - Radioisotopes
MH  - Risk
MH  - Thallium
EDAT- 1987/07/01 00:00
MHDA- 1987/07/01 00:01
CRDT- 1987/07/01 00:00
PHST- 1987/07/01 00:00 [pubmed]
PHST- 1987/07/01 00:01 [medline]
PHST- 1987/07/01 00:00 [entrez]
AID - 0002-9149(87)90975-1 [pii]
AID - 10.1016/0002-9149(87)90975-1 [doi]
PST - ppublish
SO  - Am J Cardiol. 1987 Jul 1;60(1):15-9. doi: 10.1016/0002-9149(87)90975-1.