PMID- 36060668
OWN - NLM
STAT- MEDLINE
DCOM- 20220907
LR  - 20231221
IS  - 1748-6718 (Electronic)
IS  - 1748-670X (Print)
IS  - 1748-670X (Linking)
VI  - 2022
DP  - 2022
TI  - Effects of Transcranial Magnetic Stimulation Combined with Computer-Aided 
      Cognitive Training on Cognitive Function of Children with Cerebral Palsy and 
      Dysgnosia.
PG  - 5316992
LID - 10.1155/2022/5316992 [doi]
LID - 5316992
AB  - OBJECTIVE: This study is aimed at researching transcranial magnetic stimulation 
      (TMS) effects combined with computer-aided cognitive training (CACT) on cognitive 
      function of children suffering from cerebral palsy and dysgnosia. METHODS: From 
      December 2019 to October 2021, 86 children with cerebral palsy and dysgnosia who 
      were treated at our hospital were recruited and assigned into observation and 
      control groups (n = 43, each) using the random number table technique. The 
      observation group received TMS combined with CACT (TMS+CACT), whereas the control 
      group received only TMS. Chinese Wechsler Young Children Scale of Intelligence 
      (C-WYCSI) and Chinese-Wechsler Intelligence Scale for Children (C-WISC) were used 
      to evaluate the intelligence level of the two groups; Gross Motor Function 
      Measure-88 (GMFM-88) of Fudan Chinese version was employed for evaluating the 
      gross motor function of the two groups; a comparison was drawn among the two 
      groups for the cerebral hemodynamic parameters before and after the treatment. 
      RESULTS: For young children, the verbal intelligence quotient (VIQ) scores at 6 
      and 12 weeks of treatment in the observation group were increased when compared 
      to those in the control group (48.91 +/- 3.70 vs. 47.32 +/- 3.33, 54.25 +/- 4.46 vs. 
      49.48 +/- 3.36), and the observation group's performance intelligence quotient 
      (PIQ) score at 12 weeks of treatment was higher as to that of the control group 
      (65.38 +/- 4.23 vs. 62.81 +/- 4.74, all P < 0.05). For older age children, the 
      observation group's VIQ and PIQ scores were greater than the control group's at 6 
      and 12 weeks of treatment, with statistical significance (63.80 +/- 3.76 vs. 59.50 
      +/- 5.32, 74.64 +/- 12.04 vs. 65.08 +/- 6.30; 63.91 +/- 5.96 vs. 58.42 +/- 3.70, 72.73 +/- 
      5.06 vs. 66.42 +/- 5.93; all P < 0.05). The GMFM-88 scale scores in both groups 
      were increased after 6 and 12 weeks of treatment. After treatment for 12 weeks, 
      the observation group's A-E scores were greater than those of the control group 
      (all P < 0.05). The peak systolic velocity (V (s)), end-diastolic velocity (V 
      (d)), and mean velocity (V (m)) at the anterior cerebral artery (ACA), middle 
      cerebral artery (MCA), and posterior cerebral artery (PCA) in the observation 
      group were dramatically increased than those in the control group (all P < 0.05) 
      after 12 weeks of treatment. CONCLUSION: TMS+CACT can effectively improve the 
      intelligence level, cognitive ability, gross motor function, and cerebral blood 
      flow of children suffering from cerebral palsy and intellectual disability.
CI  - Copyright (c) 2022 Jun Chen et al.
FAU - Chen, Jun
AU  - Chen J
AUID- ORCID: 0000-0003-2989-2420
AD  - Department of Rehabilitation, Qingdao Women and Children's Hospital, Qingdao, 
      Shandong 266034, China.
FAU - Yu, Xiaoming
AU  - Yu X
AD  - Department of Rehabilitation, Qingdao Women and Children's Hospital, Qingdao, 
      Shandong 266034, China.
FAU - Luo, Guangjin
AU  - Luo G
AD  - Department of Rehabilitation, Qingdao Women and Children's Hospital, Qingdao, 
      Shandong 266034, China.
LA  - eng
PT  - Journal Article
PT  - Retracted Publication
DEP - 20220826
PL  - United States
TA  - Comput Math Methods Med
JT  - Computational and mathematical methods in medicine
JID - 101277751
SB  - IM
RIN - Comput Math Methods Med. 2023 Dec 13;2023:9790315. PMID: 38124934
MH  - *Cerebral Palsy/psychology/therapy
MH  - Child
MH  - Child, Preschool
MH  - Cognition
MH  - Computers
MH  - Humans
MH  - Intelligence
MH  - Transcranial Magnetic Stimulation
PMC - PMC9439888
COIS- The authors declare no competing interests.
EDAT- 2022/09/06 06:00
MHDA- 2022/09/08 06:00
PMCR- 2022/08/26
CRDT- 2022/09/05 03:57
PHST- 2022/06/28 00:00 [received]
PHST- 2022/07/29 00:00 [revised]
PHST- 2022/08/08 00:00 [accepted]
PHST- 2022/09/05 03:57 [entrez]
PHST- 2022/09/06 06:00 [pubmed]
PHST- 2022/09/08 06:00 [medline]
PHST- 2022/08/26 00:00 [pmc-release]
AID - 10.1155/2022/5316992 [doi]
PST - epublish
SO  - Comput Math Methods Med. 2022 Aug 26;2022:5316992. doi: 10.1155/2022/5316992. 
      eCollection 2022.