PMID- 36061123
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220907
IS  - 2297-1769 (Print)
IS  - 2297-1769 (Electronic)
IS  - 2297-1769 (Linking)
VI  - 9
DP  - 2022
TI  - Genetic and epidemic characteristics of porcine parvovirus 7 in the Fujian and 
      Guangdong regions of southern China.
PG  - 949764
LID - 10.3389/fvets.2022.949764 [doi]
LID - 949764
AB  - Porcine parvovirus (PPV) is the primary cause of reproductive disorders in pigs. 
      The porcine parvovirus 7 (PPV7) subtype was first identified in the United States 
      in 2016. In this study, PPV7 was detected in different porcine samples, including 
      serum, feces, saliva, and milk, from 69 pig farms in the Fujian and Guangdong 
      regions of South China, and its coinfection with porcine circovirus 2 (PCV2), 
      porcine circovirus 3 (PCV3), and porcine reproductive and respiratory syndrome 
      virus (PRRSV) was determined. Whole-genome sequencing, phylogenetic analysis, and 
      recombination analysis were performed on seven isolates, with each selected 
      isolate originating from a different farm. There was a high rate of PPV7 
      positivity in blood, stool, and saliva but PPV7 DNA was absent from breast milk. 
      The findings also showed that PPV7-positive samples had a high rate of 
      coinfection with PCV2, PCV3, and PRRSV. Real-time PCR was used to determine the 
      viral copy numbers of PCV2, PCV3, PRRSV, and PPV7 in serum samples and to assess 
      whether PPV7 affected PCV2, PCV3, and PRRSV viral loads. Phylogenetic analysis 
      showed that PPV7e and PPV7f were the most prevalent and widespread subtypes in 
      the Fujian and Guangdong regions, respectively. While the PPV7a, PPV7b, PPV7c, 
      and PPV7f subtypes were most prevalent in Fujian Province, PPV7a-e subtypes were 
      prevalent in Guangdong, indicating that PPV7 has rich genetic diversity in these 
      regions. A putative recombinant strain, 21FJ09, was identified using SimPlot and 
      the Recombination Detection Program 4 software.
CI  - Copyright (c) 2022 Zhang, Zheng, Lv, Xue, Chen, Liu, Huang, Luo, Yang and Dai.
FAU - Zhang, Xinjie
AU  - Zhang X
AD  - College of Life Sciences, Longyan University, Longyan, China.
FAU - Zheng, Canyang
AU  - Zheng C
AD  - College of Life Sciences, Longyan University, Longyan, China.
FAU - Lv, Zixin
AU  - Lv Z
AD  - College of Life Sciences, Longyan University, Longyan, China.
FAU - Xue, Shaohua
AU  - Xue S
AD  - College of Life Sciences, Longyan University, Longyan, China.
FAU - Chen, Yuxuan
AU  - Chen Y
AD  - College of Life Sciences, Longyan University, Longyan, China.
FAU - Liu, Yanru
AU  - Liu Y
AD  - College of Life Sciences, Longyan University, Longyan, China.
FAU - Huang, Xirong
AU  - Huang X
AD  - College of Life Sciences, Longyan University, Longyan, China.
FAU - Luo, Guoqing
AU  - Luo G
AD  - College of Life Sciences, Longyan University, Longyan, China.
FAU - Yang, Xiaoyan
AU  - Yang X
AD  - College of Life Sciences, Longyan University, Longyan, China.
AD  - Fujian Engineering Research Center for Swine Disease Control and Prevention, 
      Longyan, China.
AD  - Fujian Provincial Key Laboratory for the Prevention and Control of Animal 
      Infectious Diseases and Biotechnology, Longyan, China.
FAU - Dai, Ailing
AU  - Dai A
AD  - College of Life Sciences, Longyan University, Longyan, China.
AD  - Fujian Engineering Research Center for Swine Disease Control and Prevention, 
      Longyan, China.
AD  - Fujian Provincial Key Laboratory for the Prevention and Control of Animal 
      Infectious Diseases and Biotechnology, Longyan, China.
LA  - eng
PT  - Journal Article
DEP - 20220817
PL  - Switzerland
TA  - Front Vet Sci
JT  - Frontiers in veterinary science
JID - 101666658
PMC - PMC9428481
OTO - NOTNLM
OT  - coinfections
OT  - genotype
OT  - molecular characterization
OT  - porcine parvovirus 7
OT  - recombination
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/09/06 06:00
MHDA- 2022/09/06 06:01
PMCR- 2022/01/01
CRDT- 2022/09/05 04:03
PHST- 2022/05/21 00:00 [received]
PHST- 2022/07/29 00:00 [accepted]
PHST- 2022/09/05 04:03 [entrez]
PHST- 2022/09/06 06:00 [pubmed]
PHST- 2022/09/06 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fvets.2022.949764 [doi]
PST - epublish
SO  - Front Vet Sci. 2022 Aug 17;9:949764. doi: 10.3389/fvets.2022.949764. eCollection 
      2022.