PMID- 36065547
OWN - NLM
STAT- MEDLINE
DCOM- 20220907
LR  - 20220907
IS  - 1952-4013 (Electronic)
IS  - 1167-1122 (Linking)
VI  - 32
IP  - 3
DP  - 2022 May 1
TI  - Atopy patch testing and associations with atopic conditions and specific IgE 
      tests: a population-based study in adolescents.
PG  - 384-393
LID - 10.1684/ejd.2022.4278 [doi]
AB  - BACKGROUND: The clinical usefulness of the atopy patch test (APT) is unclear for 
      investigating aeroallergen- and food-triggered atopic dermatitis (AD). 
      OBJECTIVES: This study aimed to assess the prevalence of positive APT reactions 
      in a population of adolescents and investigate possible associations between the 
      APT, specific serum (s) immunoglobulin E (IgE) tests, self-reported atopic 
      conditions and health-related quality of life. MATERIALS & METHODS: A 
      population-based study was performed on 211 adolescents (13-14 years old). 
      Collected data included questionnaires, an APT with food and aeroallergens and 
      s-IgE tests. RESULTS: Positive APT reactions were observed in 9.0% (19/211) of 
      the adolescents. Timothy grass was the top allergen with 11 (5.2%) positive 
      reactions, followed by cat dander (2.8%) and house dust mites (2.4%). 
      Rhinoconjunctivitis increased the odds of any positive APT (crude odds ratio: 
      3.32; 95% confidence interval [CI]: 1.17-9.40), particularly when an APT was 
      positive for aeroallergens (odds ratio: 5.02, 95% CI: 1.54-16.42). There was no 
      association between a positive APT and AD. Four adolescents without AD and no 
      IgE-sensitization had a positive APT. CONCLUSION: Based on a population of 
      adolescents, the APT is associated with rhinoconjunctivitis but not AD. This 
      finding should be taken into consideration in further attempts to clarify the 
      role of the APT in the clinical setting.
FAU - Uldahl, Ada
AU  - Uldahl A
AD  - Department of Dermatology, Skane University Hospital, Jan Waldenstoms gata 16, 
      205 02 Malmo, Sweden
FAU - Sterner, Therese
AU  - Sterner T
AD  - Department of Dermatology, Skane University Hospital, Jan Waldenstoms gata 16, 
      205 02 Malmo, Sweden
AD  - Competence Center of Allergy, Asthma and COPD, Skane Region Council, Lund, Sweden
FAU - Bruze, Magnus
AU  - Bruze M
AD  - Department of Occupational and Environmental Dermatology, Skane University 
      Hospital, Malmo, Sweden
FAU - Dahlin, Jakob
AU  - Dahlin J
AD  - Department of Occupational and Environmental Dermatology, Skane University 
      Hospital, Malmo, Sweden
FAU - Von Kobyletzki, Laura
AU  - Von Kobyletzki L
AD  - Department of Occupational and Environmental Dermatology, Skane University 
      Hospital, Malmo, Sweden
FAU - Svensson, Ake
AU  - Svensson A
AD  - Department of Dermatology, Skane University Hospital, Jan Waldenstoms gata 16, 
      205 02 Malmo, Sweden
FAU - Kiotseridis, Hampus
AU  - Kiotseridis H
AD  - Competence Center of Allergy, Asthma and COPD, Skane Region Council, Lund, Sweden
FAU - Tunsater, Alf
AU  - Tunsater A
AD  - Department of Respiratory Medicine and Allergology, Skane University Hospital, 
      Lund, Sweden
FAU - Svedman, Cecilia
AU  - Svedman C
AD  - Department of Occupational and Environmental Dermatology, Skane University 
      Hospital, Malmo, Sweden
LA  - eng
PT  - Journal Article
TT  - Atopy patch testing and associations with atopic conditions and specific IgE 
      tests: a population-based study in adolescents.
PL  - France
TA  - Eur J Dermatol
JT  - European journal of dermatology : EJD
JID - 9206420
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Allergens
MH  - *Dermatitis, Atopic/diagnosis/epidemiology
MH  - Humans
MH  - Immunoglobulin E
MH  - Patch Tests
MH  - *Quality of Life
OTO - NOTNLM
OT  - adolescents
OT  - atopic dermatitis
OT  - atopy patch test
OT  - delayed hypersensitivity
OT  - epidemiology
OT  - rhinoconjunctivitis
EDAT- 2022/09/07 06:00
MHDA- 2022/09/08 06:00
CRDT- 2022/09/06 03:01
PHST- 2022/09/06 03:01 [entrez]
PHST- 2022/09/07 06:00 [pubmed]
PHST- 2022/09/08 06:00 [medline]
AID - 10.1684/ejd.2022.4278 [doi]
PST - ppublish
SO  - Eur J Dermatol. 2022 May 1;32(3):384-393. doi: 10.1684/ejd.2022.4278.