PMID- 36069038
OWN - NLM
STAT- MEDLINE
DCOM- 20230314
LR  - 20230908
IS  - 2042-6186 (Electronic)
IS  - 1066-9817 (Print)
IS  - 1066-9817 (Linking)
VI  - 31
IP  - 2
DP  - 2023 Apr
TI  - Expectations affect pain sensitivity changes during massage.
PG  - 84-92
LID - 10.1080/10669817.2022.2118449 [doi]
AB  - BACKGROUND: Pain-inducing massage produces comparable changes in pain sensitivity 
      as a cold pressor task, suggesting shared neurophysiological mechanisms of 
      conditioned pain modulation. Manual therapy and conditioned pain modulation are 
      influenced by positive and negative expectations. Therefore, the purpose of this 
      study was to examine the effects of positive and negative expectations on 
      pain-free and pain-inducing massage. METHODS: 56 healthy participants were 
      randomly assigned to receive a positive or negative expectation instructional set 
      followed by a pain-inducing or a pain-free massage. Pressure pain threshold (PPT) 
      was measured followed by each interval of massage. A repeated measures ANCOVA 
      controlling for post-randomization differences in sex tested for massage x 
      expectation set x PPT interaction effects, as well as two-way interaction 
      effects. RESULTS: A significant three-way interaction effect (p = 0.04) and time 
      x expectation interaction effect was observed for individuals receiving pain 
      inducing massage (p = 0.02). Individuals who received the positive expectation 
      instructional set demonstrated significantly higher PPT at minutes 3 and 4 of 
      massage compared to individuals who received the negative expectation 
      instructional set. CONCLUSIONS: Expectations impact pain sensitivity changes 
      produced during massage. Clinicians planning to provide pain-inducing massage 
      should consider the role of expectations in modulating pain sensitivity changes.
FAU - Wilson, Abigail T
AU  - Wilson AT
AUID- ORCID: 0000-0001-9740-5917
AD  - School of Kinesiology and Physical Therapy, College of Health Professions and 
      Sciences, University of Central Florida, Orlando, FL, USA.
AD  - Musculoskeletal Research Laboratory, Institute of Exercise Physiology and 
      Rehabilitation Science, University of Central Florida, Orlando, Florida.
FAU - Bishop, Mark D
AU  - Bishop MD
AD  - Department of Physical Therapy, University of Florida, Gainesville, FL, USA.
AD  - Pain Research & Intervention Center of Excellence, University of Florida, 
      Gainesville, FL, USA.
FAU - Beneciuk, Jason M
AU  - Beneciuk JM
AD  - Department of Physical Therapy, University of Florida, Gainesville, FL, USA.
AD  - Clinical Research Center, Brooks Rehabilitation, Jacksonville, FL.
FAU - Tilley, Hannah E
AU  - Tilley HE
AD  - Department of Physical Therapy, University of Florida, Gainesville, FL, USA.
FAU - Riley, Joseph L 3rd
AU  - Riley JL 3rd
AD  - Pain Research & Intervention Center of Excellence, University of Florida, 
      Gainesville, FL, USA.
AD  - Department of Community Dentistry and Behavioral Science, University of Florida, 
      Gainesville, FL, USA.
FAU - Cruz-Almeida, Yenisel
AU  - Cruz-Almeida Y
AD  - Pain Research & Intervention Center of Excellence, University of Florida, 
      Gainesville, FL, USA.
AD  - Department of Community Dentistry and Behavioral Science, University of Florida, 
      Gainesville, FL, USA.
FAU - Bialosky, Joel E
AU  - Bialosky JE
AD  - Department of Physical Therapy, University of Florida, Gainesville, FL, USA.
AD  - Clinical Research Center, Brooks Rehabilitation, Jacksonville, FL.
LA  - eng
SI  - ClinicalTrials.gov/NCT04108403
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20220907
PL  - England
TA  - J Man Manip Ther
JT  - The Journal of manual & manipulative therapy
JID - 9433812
SB  - IM
MH  - Humans
MH  - *Pain Threshold/physiology
MH  - *Motivation
MH  - Pain
MH  - Pain Measurement
MH  - Massage
PMC - PMC10013429
OTO - NOTNLM
OT  - Expectations
OT  - conditioned pain modulation
OT  - massage
OT  - pressure pain threshold
COIS- No potential conflict of interest was reported by the author(s).
EDAT- 2022/09/08 06:00
MHDA- 2023/03/15 06:00
PMCR- 2023/09/07
CRDT- 2022/09/07 03:23
PHST- 2022/09/08 06:00 [pubmed]
PHST- 2023/03/15 06:00 [medline]
PHST- 2022/09/07 03:23 [entrez]
PHST- 2023/09/07 00:00 [pmc-release]
AID - 2118449 [pii]
AID - 10.1080/10669817.2022.2118449 [doi]
PST - ppublish
SO  - J Man Manip Ther. 2023 Apr;31(2):84-92. doi: 10.1080/10669817.2022.2118449. Epub 
      2022 Sep 7.