PMID- 36083433
OWN - NLM
STAT- MEDLINE
DCOM- 20230112
LR  - 20230112
IS  - 1559-0291 (Electronic)
IS  - 0273-2289 (Linking)
VI  - 195
IP  - 1
DP  - 2023 Jan
TI  - Eco-friendly Green Synthesis of Silver Nanoparticles from Leaf Extract of Solanum 
      khasianum: Optical Properties and Biological Applications.
PG  - 353-368
LID - 10.1007/s12010-022-04156-4 [doi]
AB  - The green synthesis of silver nanoparticles (AgNPs) was considered to be 
      efficacious over other approaches due to their eco-friendliness, 
      cost-effectiveness, and high stability. The biosynthesis of AgNPs was achieved by 
      the reduction of silver nitrate using the aqueous leaf extract of Solanum 
      khasianum. The biosynthesized AgNPs were examined by a color change and UV-Vis 
      spectroscopy with an absorption spectrum at 440 nm. The biomolecules existing in 
      S. khasianum leaf extract accountable for bioreduction and capping of AgNPs were 
      analyzed by FTIR analysis and confirmed the presence of alcohols, phenols, 
      alkanes, carboxylic acid, nitro compounds, and amines. The crystalline nature of 
      Sk-AgNPs with face-centered cubic lattice was confirmed by X-ray diffraction 
      (XRD) spectrum. The average crystallite size of Sk-AgNPs was computed as 
      15.96 nm. The lattice constant, unit cell volume, and spacing values of Sk-AgNPs 
      were parallel to the values indexed in the Joint Committee on Powder Diffraction 
      Standard of silver (JCPDS-04-0783). Scanning electron microscope (SEM) imaging 
      witnessed the spherical structure of synthesized AgNPs. Energy dispersive X-ray 
      (EDX) spectrum acknowledged the AgNPs fabrication with strong signals of silver 
      atoms at 3 keV energy. The biofabricated Sk-AgNPs showed a photoluminescence (PL) 
      emission spectrum of 445 nm with an excitation at 330 nm. Sk-AgNPs showed 
      considerable DPPH radical scavenging activity (87.98%) than BHT (86.14%) and also 
      exhibited significant antidiabetic activity compared to acarbose. Sk-AgNPs 
      revealed antibacterial potentiality against B. sphaericus, E. coli, S. aureus, 
      and P. fluorescens. Moreover, Sk-AgNPs showed dose-dependent cytotoxicity against 
      MCF-7 cell line. This method of green synthesis would support the eco-friendly 
      fabrication of AgNPs from S. khasianum leaf extract with considerable therapeutic 
      activities.
CI  - (c) 2022. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Chirumamilla, Pavani
AU  - Chirumamilla P
AD  - Department of Biotechnology, Kakatiya University, Warangal, 506009, TS, India.
AD  - Department of Biotechnology, Singareni Collieries Women's College, Khammam, 
      Telangana State, India.
FAU - Dharavath, Sunitha Bai
AU  - Dharavath SB
AD  - Department of Biotechnology, Kakatiya University, Warangal, 506009, TS, India.
FAU - Taduri, Shasthree
AU  - Taduri S
AD  - Department of Biotechnology, Kakatiya University, Warangal, 506009, TS, India. 
      tadurishasthree@kakatiya.ac.in.
LA  - eng
PT  - Journal Article
DEP - 20220909
PL  - United States
TA  - Appl Biochem Biotechnol
JT  - Applied biochemistry and biotechnology
JID - 8208561
RN  - 3M4G523W1G (Silver)
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Plant Extracts)
SB  - IM
MH  - *Metal Nanoparticles/chemistry
MH  - Escherichia coli
MH  - *Solanum
MH  - Staphylococcus aureus
MH  - Silver/pharmacology
MH  - Anti-Bacterial Agents/chemistry
MH  - Plant Extracts/pharmacology/chemistry
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Green Chemistry Technology
OTO - NOTNLM
OT  - Antibacterial
OT  - Antidiabetic
OT  - Antioxidant
OT  - Leaf extract
OT  - Phytochemical
OT  - Silver nanoparticles
OT  - Solanum khasianum
EDAT- 2022/09/10 06:00
MHDA- 2023/01/13 06:00
CRDT- 2022/09/09 11:21
PHST- 2022/08/28 00:00 [accepted]
PHST- 2022/09/10 06:00 [pubmed]
PHST- 2023/01/13 06:00 [medline]
PHST- 2022/09/09 11:21 [entrez]
AID - 10.1007/s12010-022-04156-4 [pii]
AID - 10.1007/s12010-022-04156-4 [doi]
PST - ppublish
SO  - Appl Biochem Biotechnol. 2023 Jan;195(1):353-368. doi: 
      10.1007/s12010-022-04156-4. Epub 2022 Sep 9.