PMID- 36085375 OWN - NLM STAT- MEDLINE DCOM- 20230502 LR - 20230524 IS - 2366-0058 (Electronic) VI - 48 IP - 5 DP - 2023 May TI - Perinephric myxoid pseudotumor of fat: a multimodality imaging case series. PG - 1820-1830 LID - 10.1007/s00261-022-03662-7 [doi] AB - Perinephric myxoid pseudotumor of fat (PMPF) is an unusual clinical entity with few prior imaging case reports. We report a multimodality imaging case series of PMPF, consisting of four cases seen in our department with both imaging studies and histopathologic confirmation. Three of the four patients had a history of advanced non-neoplastic renal disease. The perirenal masses in these cases varied in size and appearance. Some lesions resembled cysts or contained macroscopic fat. Enhancement was equivocal on CT, but prominent in one case on MRI and in another on contrast-enhanced ultrasound. Although not known to be malignant, PMPF may be confused for a cyst, liposarcoma, or hypovascular solid neoplasm on imaging. The dominant mass was resected in two cases because of concern for malignancy, while percutaneous CT-guided biopsy was performed in the other two. Mouse double minute 2 (MDM2) gene amplification by fluorescence in situ hybridization (FISH) was negative in all four cases, excluding well-differentiated liposarcoma. Radiologists should be familiar with PMPF to provide appropriate guidance on clinical management. CI - (c) 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. FAU - Lee, Justin AU - Lee J AUID- ORCID: 0000-0002-2231-4831 AD - Department of Radiology, Keck School of Medicine of USC, Los Angeles, CA, USA. FAU - King, Kevin G AU - King KG AUID- ORCID: 0000-0002-9107-2207 AD - Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. FAU - Chopra, Shefali AU - Chopra S AUID- ORCID: 0000-0003-3611-626X AD - Department of Pathology, Keck School of Medicine of USC, Los Angeles, CA, USA. FAU - Cheng, Phillip M AU - Cheng PM AUID- ORCID: 0000-0002-8559-7031 AD - Department of Radiology, Keck School of Medicine of USC, 1441 Eastlake Ave., Suite 2315B, Los Angeles, CA, 90033, USA. Phillip.Cheng@med.usc.edu. LA - eng PT - Journal Article DEP - 20220909 PL - United States TA - Abdom Radiol (NY) JT - Abdominal radiology (New York) JID - 101674571 SB - IM EIN - Abdom Radiol (NY). 2023 Feb 17;:. PMID: 36799999 MH - Animals MH - Mice MH - *Retroperitoneal Neoplasms/pathology MH - In Situ Hybridization, Fluorescence MH - *Liposarcoma/diagnostic imaging/surgery/pathology MH - Tomography, X-Ray Computed MH - *Cysts OTO - NOTNLM OT - Magnetic resonance imaging OT - Perinephric myxoid pseudotumor of fat OT - Retroperitoneal space OT - Ultrasonography OT - X-ray computed tomography EDAT- 2022/09/11 06:00 MHDA- 2023/05/02 06:41 CRDT- 2022/09/10 00:01 PHST- 2022/06/01 00:00 [received] PHST- 2022/08/23 00:00 [accepted] PHST- 2022/08/20 00:00 [revised] PHST- 2023/05/02 06:41 [medline] PHST- 2022/09/11 06:00 [pubmed] PHST- 2022/09/10 00:01 [entrez] AID - 10.1007/s00261-022-03662-7 [pii] AID - 10.1007/s00261-022-03662-7 [doi] PST - ppublish SO - Abdom Radiol (NY). 2023 May;48(5):1820-1830. doi: 10.1007/s00261-022-03662-7. Epub 2022 Sep 9.