PMID- 36089717
OWN - NLM
STAT- MEDLINE
DCOM- 20220913
LR  - 20220913
IS  - 1681-7168 (Electronic)
IS  - 1022-386X (Linking)
VI  - 32
IP  - 9
DP  - 2022 Sep
TI  - Effects of Low-intensity Extracorporeal Shockwave Therapy on Erectile 
      Dysfunction: A Systematic Review and Meta-analysis.
PG  - 1181-1186
LID - 10.29271/jcpsp.2022.09.1181 [doi]
AB  - This present systemic review and meta-analysis was conducted to assess the 
      effectiveness of low-intensity extracorporeal shockwave therapy (Li-ESWT) on 
      erectile dysfunction (ED) based on the relevant randomised controlled trials 
      (RCTs). A comprehensive search of databases, including Medline and Embase 
      databases, from 1st January 2012 to 31st July 2020, that investigated the 
      efficacy of Li-ESWT for ED, was searched. All the trials were divided into two 
      groups: the experimental group received a different shockwave treatment, and the 
      control group received the same treatment as the corresponding experimental group 
      vibration, sound, etc) but no energy transmission. The primary endpoint was the 
      International Index of Erectile Function-Erectile Function domain (IIEF-EF) 
      score/questionnaire or erectile hardness score (EHS). The average IIEF-EF score 
      was increased with statistical significance in the Li-ESWT group relative to the 
      control group (p<0.001). Besides, the Li-ESWT group had evidently elevated 
      changes in IIEF-EF score (p<0.001). Altogether seven articles reported the 
      remarkably elevated EHS score with different total pulses (p<0.001). The 
      favourable outcomes in terms of the average IIEF scores were observed in the 
      cases developing mild or moderate ED (p<0.001). Compared with placebo treatment, 
      Li-ESWT alleviates ED symptoms in patients, particularly those who have mild or 
      moderate ED. Taken together, these results suggest that the Li-ESWT may hold 
      promise for patients with ED. Key Words: Erectile dysfunction, Low-intensity 
      extracorporeal shockwave therapy, Meta-analysis, Randomised controlled trials.
FAU - Liu, Shuai
AU  - Liu S
AD  - Department of Urology, Lanzhou University Second Hospital, Lanzhou City, China.
FAU - Pu, Jiuzhou
AU  - Pu J
AD  - Department of Urology, Lanzhou University Second Hospital, Lanzhou City, China.
FAU - Li, Xu
AU  - Li X
AD  - Department of Urology, Lanzhou University Second Hospital, Lanzhou City, China.
FAU - Li, Rongxin
AU  - Li R
AD  - Department of Urology, Lanzhou University Second Hospital, Lanzhou City, China.
FAU - Wang, Yanan
AU  - Wang Y
AD  - Department of Urology, Lanzhou University Second Hospital, Lanzhou City, China.
FAU - Dong, Zhilong
AU  - Dong Z
AD  - Department of Urology, Lanzhou University Second Hospital, Lanzhou City, China.
LA  - eng
PT  - Meta-Analysis
PT  - Systematic Review
PL  - Pakistan
TA  - J Coll Physicians Surg Pak
JT  - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
JID - 9606447
SB  - IM
MH  - *Erectile Dysfunction/therapy
MH  - *Extracorporeal Shockwave Therapy
MH  - Humans
MH  - Male
MH  - Penile Erection
MH  - Treatment Outcome
EDAT- 2022/09/13 06:00
MHDA- 2022/09/14 06:00
CRDT- 2022/09/12 00:41
PHST- 2021/03/13 00:00 [received]
PHST- 2021/12/20 00:00 [accepted]
PHST- 2022/09/12 00:41 [entrez]
PHST- 2022/09/13 06:00 [pubmed]
PHST- 2022/09/14 06:00 [medline]
AID - 040579197 [pii]
AID - 10.29271/jcpsp.2022.09.1181 [doi]
PST - ppublish
SO  - J Coll Physicians Surg Pak. 2022 Sep;32(9):1181-1186. doi: 
      10.29271/jcpsp.2022.09.1181.