PMID- 36094367
OWN - NLM
STAT- MEDLINE
DCOM- 20221104
LR  - 20230318
IS  - 1973-9095 (Electronic)
IS  - 1973-9087 (Print)
IS  - 1973-9087 (Linking)
VI  - 58
IP  - 5
DP  - 2022 Oct
TI  - Effect of single end-range and not end-range Maitland mobilization on pressure 
      pain threshold and functional measures in knee osteoarthritis: randomised, 
      controlled clinical trial.
PG  - 774-783
LID - 10.23736/S1973-9087.22.07506-2 [doi]
AB  - BACKGROUND: Hyperalgesia is attributed to peripheral and central sensitization in 
      knee osteoarthritis (OA). Pressure pain threshold (PPT) is a relevant method for 
      evaluating pain sensitivity in knee OA. The effect of end-range and not end-range 
      Maitland mobilization for certain time-period on pain sensitivity has not been 
      investigated in knee OA. AIM: The aim of this study was to investigate the effect 
      of end-range and not end-range Maitland mobilization compared to sham manual 
      therapy technique on PPT and functional measures. DESIGN: Randomised, controlled 
      clinical trial. SETTING: Outpatient setting. POPULATION: Sixty-six patients with 
      mild-to-severe knee OA. METHODS: Twenty-one patients (N.=21) received end-range 
      Maitland mobilization (EMGr), twenty patients (N.=20) received not end-range 
      Maitland mobilization (nEMGr) and twenty-two patients (N.=22) received sham 
      manual therapy technique (CG). All interventions were performed once. Evaluation 
      was conducted pre-, postintervention and on the following consecutive second days 
      within a 6-day period. Outcomes were local and distant PPT, Timed Up and Go Test 
      (TUG) and strength of passive resistance of knee at onset of pain. RESULTS: Local 
      and distant PPT increased, TUG time and strength of passive resistance decreased 
      immediately, local and distant PPT remained decreased in 6-day and 4-day period, 
      TUG time remained decreased in 6-day period in EMGr (all changes P</=0.017). Local 
      PPT increased immediately compared to baseline in nEMGr. In between group 
      comparison, increase of local, distant PPT and strength of passive resistance 
      endures on 2(nd) day, 4(th) day and postintervention, respectively, in EMGr 
      compared to CG. EMGr compared to nEMGr presented significant difference on 6(th) 
      day and 4(th) day in local and distant PPT, respectively (all changes P</=0.021). 
      NEMGr presented no significant difference compared to CG on either follow-up. 
      CONCLUSIONS: Single end-range Maitland mobilization is effective immediately and 
      in 4-day period on pain sensitization and immediately on physical function 
      compared to not end-range Maitland mobilization and sham manual therapy technique 
      in knee OA. CLINICAL REHABILITATION IMPACT: Based on the present results, 
      applying end-range Maitland mobilization is suggested on every second day to 
      maintain alleviation of pain sensitization and increasing passive knee joint 
      mobility effectively in knee OA.
FAU - Pozsgai, Miklos
AU  - Pozsgai M
AD  - Department of Balneology, Harkany Termal Rehabilitation Centre, Harkany, Hungary 
      - miklos.pozsgay@gmail.com.
AD  - Medical School, University of Pecs, Pecs, Hungary - miklos.pozsgay@gmail.com.
FAU - Udvaracz, Kyra
AU  - Udvaracz K
AD  - Faculty of Health Sciences, University of Pecs, Pecs, Hungary.
FAU - Peter, Ivan A
AU  - Peter IA
AD  - Department of Balneology, Harkany Termal Rehabilitation Centre, Harkany, Hungary.
FAU - Than, Peter
AU  - Than P
AD  - Medical School, University of Pecs, Pecs, Hungary.
AD  - Department of Orthopedics, Medical School, University of Pecs, Pecs, Hungary.
FAU - Nusser, Nora
AU  - Nusser N
AD  - Department of Balneology, Harkany Termal Rehabilitation Centre, Harkany, Hungary.
AD  - Medical School, University of Pecs, Pecs, Hungary.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20220912
PL  - Italy
TA  - Eur J Phys Rehabil Med
JT  - European journal of physical and rehabilitation medicine
JID - 101465662
SB  - IM
MH  - Humans
MH  - *Musculoskeletal Manipulations/methods
MH  - *Osteoarthritis, Knee/therapy
MH  - Pain
MH  - Pain Measurement
MH  - Pain Threshold
MH  - Postural Balance
MH  - Range of Motion, Articular
MH  - Time and Motion Studies
MH  - Treatment Outcome
PMC - PMC10019481
COIS- Conflicts of interest.-The authors certify that there is no conflict of interest 
      with any financial organization regarding the material discussed in the 
      manuscript.
EDAT- 2022/09/13 06:00
MHDA- 2022/10/13 06:00
PMCR- 2022/10/10
CRDT- 2022/09/12 09:49
PHST- 2022/09/13 06:00 [pubmed]
PHST- 2022/10/13 06:00 [medline]
PHST- 2022/09/12 09:49 [entrez]
PHST- 2022/10/10 00:00 [pmc-release]
AID - S1973-9087.22.07506-2 [pii]
AID - 7506 [pii]
AID - 10.23736/S1973-9087.22.07506-2 [doi]
PST - ppublish
SO  - Eur J Phys Rehabil Med. 2022 Oct;58(5):774-783. doi: 
      10.23736/S1973-9087.22.07506-2. Epub 2022 Sep 12.