PMID- 36100930
OWN - NLM
STAT- MEDLINE
DCOM- 20220915
LR  - 20231001
IS  - 1833-3516 (Print)
IS  - 2209-1491 (Electronic)
IS  - 1833-3516 (Linking)
VI  - 52
IP  - 3
DP  - 2022 Sep 30
TI  - Pretreatment hearing grades and hearing recovery outcomes after primary 
      hyperbaric oxygen treatment in patients with idiopathic sudden sensorineural 
      hearing loss.
PG  - 191-196
LID - 10.28920/dhm52.3.191-196 [doi]
AB  - INTRODUCTION: Previous studies suggest the effectiveness of hyperbaric oxygen 
      treatment (HBOT) in idiopathic sudden sensorineural hearing loss (ISSNHL) but it 
      is mostly used as an adjuvant and salvage treatment. This study evaluated the 
      effect of primary HBOT according to pretreatment hearing grades and hearing 
      recovery outcomes using modified Siegel's criteria in patients with ISSNHL. 
      METHODS: Fifty-nine ISSNHL patients treated with only HBOT were included. A 
      pure-tone audiogram was recorded before and after a course of HBOT (90 min at 203 
      kPa daily for 20 days). Using the modified Siegel's criteria, patients were 
      divided into groups according to hearing threshold before and after treatment. 
      RESULTS: Hearing thresholds were significantly lower after HBOT compared to 
      pre-treatment values across all patients (P < 0.001) with a median value of 
      recovery of 22.5 dB (interquartile range 12.5-33.7 dB). Significantly lower 
      hearing threshold values were recorded at 500, 1,000, 2,000, and 4,000 Hz after 
      treatment (P < 0.001). The greatest recovery was at 1,000 Hz, (change in median 
      threshold = 32 dB) but without a significant difference compared to other 
      frequencies (P = 0.10). CONCLUSIONS: HBOT is a legitimate choice as the primary 
      treatment for ISSNHL, especially if it is readily accessible, and if there are 
      contraindications for corticosteroid therapy.
CI  - Copyright: This article is the copyright of the authors who grant Diving and 
      Hyperbaric Medicine a non-exclusive licence to publish the article in electronic 
      and other forms.
FAU - Vceva, Andrijana
AU  - Vceva A
AD  - Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty, 
      University of Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
AD  - Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital 
      Centre Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
AD  - Corresponding author: Dr Anamarija Sestak, Department of Otorhinolaryngology and 
      Head and Neck Surgery, Clinical Hospital Centre Osijek, J. Huttlera 4, 31000 
      Osijek, Croatia, annamarijasestak@gmail.com.
FAU - Zubcic, Zeljko
AU  - Zubcic Z
AD  - Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty, 
      University of Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
AD  - Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital 
      Centre Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
FAU - Mihalj, Hrvoje
AU  - Mihalj H
AD  - Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty, 
      University of Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
AD  - Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital 
      Centre Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
FAU - Males, Josip
AU  - Males J
AD  - Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty, 
      University of Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
AD  - Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital 
      Centre Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
FAU - Mendes, Tihana
AU  - Mendes T
AD  - Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty, 
      University of Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
AD  - Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital 
      Centre Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
FAU - Sestak, Anamarija
AU  - Sestak A
AD  - Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty, 
      University of Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
AD  - Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital 
      Centre Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
SB  - IM
MH  - Hearing
MH  - *Hearing Loss, Sensorineural/therapy
MH  - *Hearing Loss, Sudden/therapy
MH  - Humans
MH  - *Hyperbaric Oxygenation
MH  - Retrospective Studies
PMC - PMC9722339
OTO - NOTNLM
OT  - Clinical audit
OT  - Deafness
OT  - ENT
OT  - Hyperbaric research
OT  - Otorhinolaryngology
OT  - Outcome
COIS- Conflict of interest and funding: nil
EDAT- 2022/09/14 06:00
MHDA- 2022/09/16 06:00
PMCR- 2023/09/30
CRDT- 2022/09/13 23:38
PHST- 2022/04/16 00:00 [received]
PHST- 2022/07/30 00:00 [accepted]
PHST- 2022/09/13 23:38 [entrez]
PHST- 2022/09/14 06:00 [pubmed]
PHST- 2022/09/16 06:00 [medline]
PHST- 2023/09/30 00:00 [pmc-release]
AID - 10.28920/dhm52.3.191-196 [doi]
PST - ppublish
SO  - Diving Hyperb Med. 2022 Sep 30;52(3):191-196. doi: 10.28920/dhm52.3.191-196.