PMID- 36103855
OWN - NLM
STAT- MEDLINE
DCOM- 20220916
LR  - 20221018
IS  - 1097-4180 (Electronic)
IS  - 1074-7613 (Linking)
VI  - 55
IP  - 9
DP  - 2022 Sep 13
TI  - Skip the buffet, for SPARC's sake.
PG  - 1583-1585
LID - S1074-7613(22)00405-8 [pii]
LID - 10.1016/j.immuni.2022.08.012 [doi]
AB  - Caloric restriction (CR) reduces inflammation and the incidence of chronic 
      diseases, thereby extending healthspan and lifespan. In this issue of Immunity, 
      Ryu et al. (2022) propose that reduction of SPARC, a matricellular protein, 
      during CR offers beneficial effects by reducing SPARC-driven inflammatory 
      phenotypes in macrophages.
CI  - Copyright (c) 2022. Published by Elsevier Inc.
FAU - Zhai, Lukai
AU  - Zhai L
AD  - Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand 
      Rapids, MI 49503, USA.
FAU - Krawczyk, Connie M
AU  - Krawczyk CM
AD  - Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand 
      Rapids, MI 49503, USA. Electronic address: connie.krawczyk@vai.org.
LA  - eng
PT  - Comment
PT  - Journal Article
PL  - United States
TA  - Immunity
JT  - Immunity
JID - 9432918
RN  - 0 (Osteonectin)
RN  - 0 (SPARC protein, human)
SB  - IM
CON - Immunity. 2022 Sep 13;55(9):1609-1626.e7. PMID: 35963236
MH  - *Caloric Restriction
MH  - Humans
MH  - Inflammation
MH  - *Longevity
MH  - Osteonectin/genetics
COIS- Declaration of interests C.M.K. is an adjunct professor at McGill University, 
      Canada.
EDAT- 2022/09/15 06:00
MHDA- 2022/09/17 06:00
CRDT- 2022/09/14 18:23
PHST- 2022/09/14 18:23 [entrez]
PHST- 2022/09/15 06:00 [pubmed]
PHST- 2022/09/17 06:00 [medline]
AID - S1074-7613(22)00405-8 [pii]
AID - 10.1016/j.immuni.2022.08.012 [doi]
PST - ppublish
SO  - Immunity. 2022 Sep 13;55(9):1583-1585. doi: 10.1016/j.immuni.2022.08.012.