PMID- 36104691
OWN - NLM
STAT- MEDLINE
DCOM- 20220916
LR  - 20220918
IS  - 1465-993X (Electronic)
IS  - 1465-9921 (Print)
IS  - 1465-9921 (Linking)
VI  - 23
IP  - 1
DP  - 2022 Sep 14
TI  - Hierarchical clock-scale hand-drawn mapping as a simple method for bronchoscopic 
      navigation in peripheral pulmonary nodule.
PG  - 245
LID - 10.1186/s12931-022-02160-0 [doi]
LID - 245
AB  - BACKGROUND: A feasible and economical bronchoscopic navigation method in guiding 
      peripheral pulmonary nodule biopsy is lacking. OBJECTIVE: To investigate the 
      utility of hierarchical clock-scale hand-drawn mapping for bronchoscopic 
      navigation in peripheral pulmonary nodules. METHODS: We developed a hierarchical 
      clock-scale hand-drawn mapping for bronchoscopic navigation in peripheral 
      pulmonary nodules. Patients with peripheral pulmonary nodules were recruited and 
      assigned to two groups in this retrospective study, subjects in VBN group 
      received conventional bronchoscopy in conjunction with virtual bronchoscopic 
      navigation (VBN) and radial probe endobronchial ultrasound (RP-EBUS) for biopsy 
      (VBN group), while HBN group underwent ultrathin bronchoscopy and RP-EBUS under 
      the guidance of hand-drawn bronchoscopic navigation (HBN). The demographic 
      characteristics, procedural time, operating cost and diagnostic yield were 
      compared between these two groups. RESULTS: Forty-eight patients with peripheral 
      pulmonary nodule were enrolled in HBN group, while 42 in VBN group. There were no 
      significant differences between VBN and HBN groups in terms of age, gender, 
      lesion size, location and radiographic type. The time of planning pathway (1.32 
      vs. 9.79 min, P < 0.001) and total operation (23.63 vs. 28.02 min, P = 0.002), as 
      well as operating cost (758.31 +/- 125.21 vs.1327.70 +/- 116.25 USD, P < 0.001) were 
      markedly less in HBN group, compared with those in VBN group. The pathological 
      diagnostic efficiency of benign and malignant disease in HBN group appeared 
      similar with those in VBN group, irrespective of the size of pulmonary lesion 
      (larger or smaller than 20 mm). The total diagnostic yield of HBN had no marked 
      difference from that of VBN (75.00% vs. 61.90%, P = 0.25). CONCLUSIONS: 
      Hierarchical clock-scale hand-drawn mapping for bronchoscopic navigation could 
      serve as a feasible and economical method for guiding peripheral pulmonary nodule 
      biopsy, providing a comparable diagnostic yield in comparison with virtual 
      bronchoscopic navigation.
CI  - (c) 2022. The Author(s).
FAU - Zhong, Chang-Hao
AU  - Zhong CH
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Su, Zhu-Quan
AU  - Su ZQ
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Luo, Wei-Zhan
AU  - Luo WZ
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Rao, Wan-Yuan
AU  - Rao WY
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Feng, Jia-Xin
AU  - Feng JX
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Tang, Chun-Li
AU  - Tang CL
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Chen, Yu
AU  - Chen Y
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Chen, Xiao-Bo
AU  - Chen XB
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Fan, Ming-Yue
AU  - Fan MY
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China.
FAU - Li, Shi-Yue
AU  - Li SY
AD  - State Key Laboratory of Respiratory Disease, National Clinical Research Center 
      for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First 
      Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, 
      Guangzhou, 510120, China. lishiyue@188.com.
LA  - eng
GR  - No.81900032/National Natural Science Foundation of China/
GR  - No.81770017/National Natural Science Foundation of China/
PT  - Journal Article
DEP - 20220914
PL  - England
TA  - Respir Res
JT  - Respiratory research
JID - 101090633
SB  - IM
MH  - Bronchoscopy/methods
MH  - Endosonography/methods
MH  - Humans
MH  - Lung/pathology
MH  - *Lung Neoplasms/diagnostic imaging/surgery
MH  - Retrospective Studies
PMC - PMC9472376
OTO - NOTNLM
OT  - Bronchoscopy
OT  - Diagnostic yield
OT  - Hand-drawn bronchoscopic navigation
OT  - Peripheral pulmonary nodule
OT  - Virtual bronchoscopic navigation
COIS- The authors declare that they have no competing interests.
EDAT- 2022/09/15 06:00
MHDA- 2022/09/17 06:00
PMCR- 2022/09/14
CRDT- 2022/09/14 23:40
PHST- 2021/12/30 00:00 [received]
PHST- 2022/08/15 00:00 [accepted]
PHST- 2022/09/14 23:40 [entrez]
PHST- 2022/09/15 06:00 [pubmed]
PHST- 2022/09/17 06:00 [medline]
PHST- 2022/09/14 00:00 [pmc-release]
AID - 10.1186/s12931-022-02160-0 [pii]
AID - 2160 [pii]
AID - 10.1186/s12931-022-02160-0 [doi]
PST - epublish
SO  - Respir Res. 2022 Sep 14;23(1):245. doi: 10.1186/s12931-022-02160-0.